Research Progress of High-dose Dual Therapy in Eradication of Helicobacter pylori Infection
10.3969/j.issn.1008-7125.2021.09.006
- Author:
Hanxin BI
1
;
Yuxin CHEN
1
;
Xin ZHAO
1
;
Yongquan SHI
1
;
Yongquan SHI
2
Author Information
1. Xi'an Medical University
2. Department of Gastroenterology, Xijing Hospital, Air Force Medical University
- Publication Type:Journal Article
- Keywords:
Drug Resistance;
Helicobacter pylori;
High-Dose Dual Therapy;
Therapy
- From:
Chinese Journal of Gastroenterology
2021;26(9):554-559
- CountryChina
- Language:Chinese
-
Abstract:
In the era of increasing of antibiotic resistance, Helicobacter pylori (Hp) eradication rates of traditional triple and quadruple therapy are gradually declining. High-dose dual therapy (HDDT) containing proton pump inhibitors and amoxicillin may be a new breakthrough in eradicating Hp infection. Current research shows that HDDT, whether used as a first-line regimen or a rescue regimen, has a high eradication rate and a low incidence of adverse reactions. It has the potential to become a new first-line eradication therapy or rescue therapy for Hp infection in clinical practice. This article reviewed the research progress of HDDT in eradication of Hp infection.
