Drug-induced Intestinal Mucosal Injury
10.3969/j.issn.1008-7125.2021.11.001
- Author:
Sixue LIU
1
;
Yingqiang ZHONG
1
Author Information
1. Department of Gastroenterology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University
- Publication Type:Journal Article
- Keywords:
Diagnosis;
Drugs;
Enterocolitis;
Intestinal Mucosa;
Therapy
- From:
Chinese Journal of Gastroenterology
2021;26(11):641-646
- CountryChina
- Language:Chinese
-
Abstract:
Drug-induced intestinal mucosal injury is a commonly seen adverse event with the exposure to various drugs. During the course of drug therapy, when exacerbation of primary gastrointestinal disease or new onset of gastro-intestinal symptoms occurs, drug-induced injury should be considered. Patients should be evaluated by gastrointestinal endoscopy for confirming the diagnosis. In this article, the etiologic and pathogenic factors, as well as the diagnostic and therapeutic approaches of four commonly seen drug-induced intestinal mucosal injuries, which were caused by nonsteroidal anti-inflammatory drugs, chemotherapeutic agents, immune checkpoint inhibitors and antibiotics were reviewed.
