LPA
10.13865/j.cnki.cjbmb.2021.06.1270
- Author:
Si LIU
1
;
Fang WANG
2
;
Sheng-Qiang PEI
2
;
Jian-Qiu PEI
2
;
Xiang-Feng CONG
2
;
Xi CHEN
2
Author Information
1. Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease
2. State Key Laboratory of Cardiovascular Disease, Center of Laboratory Medicine, Fuwai Hospital, National Center for CardiovascularDiseases, Chinese Academy of Medical Sciences, Peking Union Medical College
- Publication Type:Journal Article
- Keywords:
cardiac function;
cardiac infraction;
cardiomyocyte;
lysophosphatidic acid (LPA)
- From:
Chinese Journal of Biochemistry and Molecular Biology
2021;37(8):1032-1039
- CountryChina
- Language:Chinese
-
Abstract:
Lysophosphatidic acid(LPA)is a small bioactive phospholipid that mediates various cellular processes such as proliferation, survival, and migration. In particular, LPA signaling has been shown to affect the development of diverse tissues. Our previous work demonstrated that LPA could promote primary neonatal rat cardiomyocytes proliferation. However, the role of LPA and its receptor in postnatal heart de-velopment is unknown. By using databases for biological information and RT-qPCR, we analyzed the ex-pression of six LPA receptors (LPA
