Drug-induced dysphagia risk in elder people——A pharmacovigilance study of FDA Adverse Event Reporting System (FAERS) database
10.12092/j.issn.1009-2501.2023.10.004
- Author:
Boying JIA
1
;
Liyan WAN
1
;
Shuang ZHOU
2
;
Ying ZHOU
2
;
Yimin CUI
2
Author Information
1. Department of Pharmacy, The First Hospital of Tsinghua University
2. Department of Pharmacy, Peking University First Hospital
- Publication Type:Journal Article
- Keywords:
drug safety;
drug-induced dysphagia;
elder patients;
FARES;
pharmacovigilance
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2023;28(10):1109-1120
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To evaluate the risk of drug-related dysphagia in elder people based on the FDA Adverse Event Reporting System (FAERS). METHODS: We collected the reports of dysphagia in elder people (Age≥65) from 2004 quarter 1 through 2022 quarter 2 of FAERS by Open Vigil 2.1 database. The reported odds ratio (ROR) and the proportional reported ratio (PRR) were calculated to detect the adverse reaction signal of drug-induced dysphagia in elder people. Signal generation standard of ROR: number of reports≥3 with the lower limit of 95% confidence interval (CI) of the ROR value>1, PRR≥2 and c
