FoxO1 regulates Hcyinduced hepatocyte apoptosis through ATF6

Author: Qing-Qing WANG ¹ ; Xin-Yan WU ¹ ; Long XU ¹ ; Hui ZHANG ¹ ; Wei GUO ¹ ; Yi-Deng JIANG ¹ ; Yun JIAO ² ; Xiu-Ling HAI ² ; Yi HAO ³ ; Yi-Deng JIANG ⁴ ; Yi-Deng JIANG ⁵
Author Information

1. School of Basic Medicine, Ningxia Medical University
2. Dept of Infectious Diseases, General Hospital of Ningxia Medical, Ningxia Medical University
3. School of Pharmacy, Ningxia Medical University
4. Ningxia Key Lab of Vascular Injury and Repair Research, Ningxia Medical University
5. Key Lab of Metabolic Cardiovascular Disease Research, National Health Commission, Ningxia Medical University
Publication Type:Journal Article
Keywords: ATF6; endoplasmic reticulum stress; FoxO1; hepatocyte apoptosis; homocysteine; liver damage
From: Chinese Pharmacological Bulletin 2021;37(2):203-209
CountryChina
Language:Chinese
Abstract: : Aim To explore the role and possible mechanism of forked transcription factor (FoxO1) in hepatocyte apoptosis induced by homocysteine (Hey) . Methods The male cbs