Screening of key targets for diabetic cardiomyopathy based on transcriptomics and proteomics

Author: Zhen-Ming LIN ¹ ; Ming-Chao ZHANG ¹ ; Meng-Ying HE ¹ ; Wen-Bin LIU ¹ ; Juan SHEN ¹ ; Xiao-Bao JIN ¹
Author Information

1. Guangdong Province Key Laboratory of Pharmaceutical Bioactive Substances, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University
Publication Type:Journal Article
Keywords: ACOT2; diabetic cardiomyopathy (DCM); GO enrichment analysis; KEGG enrichment analysis; Proteomics; Transcriptomics
From: Chinese Pharmacological Bulletin 2023;39(5):910-917
CountryChina
Language:Chinese
Abstract: Aim To explore a potential new target for the prevention and treatment of diabetic cardiomyopathy ( DCM) in mice. Methods The myocardial proteomics of normal and diabetic mice was studied. The GEO database GSE161931 dataset was analyzed using R language with P < 0.05 and I log