The protective effect of orcinol glucoside on dexamethasone induced osteoblast cell damage through inhibition of glucocorticoid receptor nucleus translocation
- Author:
Xin-Yun-Xi HE
1
;
Wan-Lu ZHAO
1
;
Yang YU
1
;
Yan LIU
1
;
Qiao-Yan ZHANG
1
;
Quan-Long ZHANG
1
;
Lu-Ping QIN
1
Author Information
- Publication Type:Journal Article
- Keywords: Curculigo orchioides; dexamethasone; glucocorticoid; glucocorticoid receptor; orcinol glucoside; osteoblast
- From: Chinese Pharmacological Bulletin 2023;39(7):1346-1353
- CountryChina
- Language:Chinese
- Abstract: Aim To investigate the protective effect of orcinol glucoside on dexamethasone(DEX)-induced osteoblast injury and its mechanism. Methods Primary osteoblasts were extracted from calvaria of neonatal mice and cultured in medium with DEX(1 μmol•L
