Observation of the prophylactic use of prokinetic agents in patients after tricuspid valve replacement under cardiopulmonary bypass
10.12206/j.issn.2097-2024.202210060
- VernacularTitle:体外循环下三尖瓣置换术后患者预防性使用胃肠动力药的疗效观察
- Author:
Qian CHEN
1
;
Xiangyang XU
2
;
Fanglin LU
2
;
Lin HAN
2
;
Bailing LI
2
;
Zhiyun XU
2
Author Information
1. Department of Cardio-thoracic Surgery, No. 904 Hospital of Joint Logistic Support Force, Wuxi 214000, China;Department of Cardiovascular Surgery，the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China.
2. Department of Cardiovascular Surgery，the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China.
- Keywords:
prokinetic agents;
tricuspid valve replacement;
clinical effect;
retrospective study
- From:
Journal of Pharmaceutical Practice and Service
2024;42(3):131-134
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the postoperative therapeutic effect of prokinetic agents in patients after tricuspid valve replacement （TVR） under cardiopulmonary bypass. Methods Patients received TVR under cardiopulmonary bypass （during June 2010 to December 2021） in the department of Cardiovascular Surgery of the First Affiliated Hospital of Naval Medical University were selected as the subjects of our study. The data of basic characteristics, first postoperative defecation time and postoperative recovery condition were collected and retrospectively analyzed in the patients taking prokinetic agents within three days after surgery （prevention group） and patients not taking prokinetic agents within three days after surgery （control group）. Results A total of 184 patients were selected, including 101 in the prevention group and 83 in the control group. The first defecation time of patients in the prevention group was significantly earlier than that in the control group （P<0.05）. The incidences of abdominal distension and pulmonary infection in the prevention group were significantly lower than that in the control group. The length of time in ICU, postoperative mechanical ventilation and nasogastric tube decompression in the prevention group were significantly shorter than that in the control group （P<0.05）. Conclusion Taking prokinetic agents within three days after TVR under cardiopulmonary bypass could effectively improve the prognosis of patients.
