Interpretation of histiocytic/dendritic cell neoplasms and stromal-derived neoplasms of lymphoid tissues in the 5th edition of WHO classification of haematolymphoid tumors
10.3760/cma.j.cn112151-20230907-00150
- VernacularTitle:第5版WHO造血与淋巴组织肿瘤分类组织细胞/树突细胞肿瘤及淋巴组织间质源性肿瘤解读
- Author:
Weihua YIN
1
;
Xiaoqiu LI
Author Information
1. 北京大学深圳医院病理科，深圳 518036
- Keywords:
Hemic and lymphatic diseases;
Molecular biology;
Dendritic cell sarcoma, follicular
- From:
Chinese Journal of Pathology
2024;53(1):12-15
- CountryChina
- Language:Chinese
-
Abstract:
The 5th edition of the World Health Organization classification of hematolymphoid tumors (WHO Blue Book) is soon to be published. Significant revisions have been made in the chapters on histiocytic/dendritic cell neoplasms and stroma-derived neoplasms of lymphoid tissues, leading to the reclassification and renaming of specific diseases. This article provides a concise interpretation and summary of these updates, highlighting the differences from the fourth edition. Pertinent changes from clinical pathological diagnosis to treatment and prognosis are explored, with an emphasis on recent advancements in molecular genetics. Newly introduced disease classifications are discussed, and the section on follicular dendritic cell sarcoma contributed by the author is detailed to assist readers in quickly understanding and assimilating the new classification standards.
