Retrospective Analysis of Death Cases of Oral Diphenidol Hydrochloride Poisoning.
10.12116/j.issn.1004-5619.2022.420401
- Author:
Yu YANG
1
;
Fan-Zhang LEI
2
;
Yu-You DONG
1
;
Jian-Long MA
1
;
Qi-Qiang SHI
3
;
Xue-Song YE
1
Author Information
1. Key Laboratory of Forensic Pathology, Ministry of Public Security, Criminal Police Detachment of Shenzhen Public Security Bureau, Institute of Criminal Science and Technology, Shenzhen Public Security Bureau, Shenzhen 518000, Guangdong Province, China.
2. School of Forensic Medicine, Southern Medical University, Guangzhou 510515, China.
3. Longgang Branch of Shenzhen Public Security Bureau, Shenzhen 518000, Guangdong Province, China.
- Publication Type:Journal Article
- Keywords:
cases analysis;
diphenidol hydrochloride;
forensic pathology;
poisoning;
postmortem examination;
scene investigation
- MeSH:
Humans;
Retrospective Studies;
Piperidines;
Autopsy;
Suicide;
Poisoning
- From:
Journal of Forensic Medicine
2023;39(4):393-398
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:To explore the characteristics of postmortem examination, chemical examination and scene investigation of deaths caused by oral diphenidol hydrochloride poisoning, and so as to provide a reference for proper settlement and prevention of such deaths.
METHODS:The data of 22 deaths caused by oral diphenidol hydrochloride poisoning in a city from January 2018 to August 2020 were collected, including case details, scene investigations, autopsies, chemical examinations and digital evidence. Thirty-one cases of deaths caused by oral diphenidol hydrochloride poisoning reported in previous literature were also collected.
RESULTS:In the 53 oral diphenidol hydrochloride poisoning death cases, 50 cases were suicide, 2 cases were accidental, while 1 case was undetermined. Fifty-two cases were found in the medical records or crime scene investigation reports with doses ranging from 775 mg to 12 500 mg, and 23 deceased were detected with postmortem blood concentrations ranging from 2.71 mg/L to 83.1 mg/L. Clinical symptoms were recorded in 6 patients, including conscious disturbance and convulsion. Among the 45 cases which were performed with external examination, 23 cases autopsied.
CONCLUSIONS:Most of the deceased of oral diphenidol hydrochloride poisoning were suicide. No significant correlation was found between dose and blood concentration through the retrospective analysis of cases.
