Syndrome differentiation and treatment of coronary heart disease combined with anxiety and depression from stages of phlegm, blood stasis, and toxic pathogen based on theory of "coexistence of diseases and depression syndromes".
10.19540/j.cnki.cjcmm.20230627.501
- Author:
Sen-Jie ZHONG
1
;
Xiang GAO
2
;
Lu-Xi WANG
3
;
Jie CHEN
2
;
Hui WU
2
;
Jing LI
4
;
Hong-Cheng FANG
5
;
Shao-Xiang XIAN
2
Author Information
1. the First Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou 510405, China Postdoctoral Research Station of Guangzhou University of Chinese Medicine Guangzhou 510006, China.
2. the First Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou 510405, China.
3. Huazhong University of Science and Technology Union Shenzhen Hospital Shenzhen 518052, China.
4. Diagnosis Institute of Traditional Chinese Medicine, Hunan University of Chinese Medicine Changsha 410208, China.
5. Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine Shenzhen 518104, China.
- Publication Type:Journal Article
- Keywords:
blood stasis;
coronary heart disease;
depression syndrome;
phlegm turbidity;
psycho-cardiology medicine;
toxic pathogen
- MeSH:
Humans;
Medicine, Chinese Traditional;
Depression/diagnosis*;
Coronary Disease/diagnosis*;
Mucus;
Syndrome;
Anxiety
- From:
China Journal of Chinese Materia Medica
2023;48(20):5675-5680
- CountryChina
- Language:Chinese
-
Abstract:
Depression syndromes(anxiety and depression), as typical psychological disorders, often coexist with and mutually influence coronary heart disease(CHD). They constitute a psycho-cardiology disease involving both the blood vessels of the heart and the spirit of the heart. Based on the theory of "coexistence of diseases and depression syndromes", it was proposed that CHD and depression syndromes coexisted independently and were causally related. The factors of depression syndromes go through the entire course of CHD and have different causal relationships at different stages, leading to a pathogenic process of "depression causing disease" or "disease causing depression". In the chronic latent period, phlegm predominates, with depression leading to the production of phlegm. Phlegm accumulation and Qi stagnation initiate a mutual damage process of psycho-cardiology, marking the onset of the disease. In the pathological development period, blood stasis becomes predominant. Depression leads to blood stasis, which further obstructs Qi circulation, accelerating disease progression. In the acute attack period, toxicity becomes crucial. Depression transforms into toxicity, damaging Qi and blood, disturbing the balance of the mind, and inducing a sudden and severe exacerbation of the disease. Based on this, the approach of treating phlegm and depression together, treating blood stasis and depression together, and treating toxicity and depression together by stages was established. Research has found that this approach can simultaneously improve organic damage and emotional disorders, and also has a regulating effect on micro-level syndrome indicators, achieving harmonization of psycho-cardiology in the treatment.
