Atypical Lymphocytosis:Report of Two Cases and Literature Review.
10.3881/j.issn.1000-503X.15301
- VernacularTitle:异型淋巴细胞增多两例并文献复习
- Author:
Ya-Xin SHAN
1
;
Jing LI
1
;
Xiang YANG
2
;
Lin LI
2
;
Zou-Fang HUANG
2
Author Information
1. The First Clinical Medical College of Gannan Medical University,Ganzhou,Jiangxi 341000,China.
2. The Endemic Disease(Thalassemia)Clinical Research Center of Jiangxi Province,Department of Hematology, First Affiliated Hospital of Gannan Medical University,Ganzhou,Jiangxi 341000,China.
- Publication Type:Journal Article
- Keywords:
NK cells;
atypical;
leukemia;
lymphocyte;
mononuclear cell
- MeSH:
Humans;
Lymphocytosis/diagnosis*;
Infectious Mononucleosis/diagnosis*;
Immunophenotyping;
Diagnosis, Differential;
Diagnostic Errors
- From:
Acta Academiae Medicinae Sinicae
2023;45(6):1005-1010
- CountryChina
- Language:Chinese
-
Abstract:
To improve the diagnosis of atypical lymphocytes and reduce the misdiagnosis rate,we analyzed the medical records of 2 cases with cell morphology suggestive of atypical lymphocytes.One case was diagnosed with infectious mononucleosis and the other with aggressive NK cell leukemia.The purpose of this paper is to emphasize that the diagnosis of atypical lymphocytes based only on morphological interpretation of cells may be incorrect,which should be combined with clinical symptoms,signs,imaging examination,cell immunophenotype,and disease outcome.