Research progress of sustained-release drug delivery system for uveitis
10.3980/j.issn.1672-5123.2024.2.11
- VernacularTitle:葡萄膜炎的缓释治疗给药研究进展
- Author:
Ting ZHU
1
;
Dahua XU
1
;
Xiaolin WANG
1
;
Mei CHEN
1
Author Information
1. Aier School of Ophthalmology, Central South University, Changsha 410009, Hunan Province, China
- Publication Type:Journal Article
- Keywords:
uveitis;
sustained-release preparations;
drug delivery system
- From:
International Eye Science
2024;24(2):236-240
- CountryChina
- Language:Chinese
-
Abstract:
Uveitis, a complex ocular disorder with numerous etiologies, can result from infection, autoimmune, and various physicochemical and mechanical injury factors. The treatment of this disease is difficult, and failure to receive timely and effective treatment can often lead to blindness. With the deepening of people's understanding of uveitis and its related mechanisms, various new sustained-release drug delivery systems for uveitis have been studied. However, due to the existence of various anatomical and physiological barriers in the eye, there are multiple obstacles to the sustained release treatment of uveitis. In this paper, the main research results in this field in recent years are reviewed, and the innovations and limitations of various new sustained-release drug delivery systems are discussed in order to provide new ideas for the sustained-release drug delivery treatment of uveitis in the future. These new sustained-release drug delivery systems will help to completely change the traditional treatment mode of uveitis with side effects and poor compliance in the future, bringing longer targeted sustained release and less toxic reactions.
