Incidence of adverse transfusion reactions in Chinese children: a meta-analysis
10.13303/j.cjbt.issn.1004-549x.2023.05.005
- VernacularTitle:我国儿童输血反应发生率的Meta分析
- Author:
Ze LI
1
;
Jiayi ZHANG
1
;
Jia MA
1
;
Qin HE
1
Author Information
1. Clinical Laboratory of Tianjin Children′s Hospital, Tianjin 300400, China
- Publication Type:Journal Article
- Keywords:
adverse transfusion reactions;
children;
incidence;
meta;
fever reaction;
anaphylaxis reaction;
blood components
- From:
Chinese Journal of Blood Transfusion
2023;36(5):384-388
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To systematically evaluate the incidence of adverse transfusion reactions in Chinese children, so as to provide scientific basis for prevention and early intervention. 【Methods】 Literature databases such as PubMed, EMbase, The Cochrane Library, CNKI, Wanfang and VIP were searched in terms of the incidence of adverse transfusion reactions in Chinese children from January 2000 to December 2022. Two researchers extracted literature data independently according to the inclusion and exclusion criteria and conducted quality evaluation of included studies according to AHRQ quality evaluation scale. Statistical analysis was performed using Stata 14.0 software. 【Results】 A total of 870 literatures were retrieved, and 13 were included in the study, with a total of 181 274 cases with blood transfusion. Meta-analysis showed that the overall incidence of adverse transfusion reactions in Chinese children was 0.79%[95%CI (0.54%, 1.04%)]. The incidence of adverse reactions of red blood cells, platelets and plasma were 0.34%[95%CI (0.15%, 0.54%)], 2.94%[95%CI (1.60%, 4.28%)] and 0.31%[95%CI (0.19%, 0.43%)], respectively. The incidence of fever reaction and anaphylaxis reaction were 0.22%[95%CI (0.13%, 0.31%)] and 0.46%[95%CI (0.30%, 0.61%)] respectively. 【Conclusion】 The overall incidence of adverse transfusion reactions in Chinese children is low, but the incidence of adverse reactions of platelet transfusion is high, which needs further prevention and control.
