Countermeasures of adverse reactions to blood donation in low-weight blood donors for the MCS+ blood cell separator UPP procedure
10.13303/j.cjbt.issn.1004-549x.2023.10.020
- VernacularTitle:低体重女性单采献血者献血不良反应的应对措施———针对MCS+血细胞分离机UPP程序
- Author:
Ye HAN
1
;
Xiaomin NIU
1
;
Chao ZHANG
1
;
Xiaoli WEI
1
;
Ying CHANG
1
Author Information
1. Hebei Province Blood Center, Shijiazhuang 050071, China
- Publication Type:Journal Article
- Keywords:
MCS blood cell separator;
UPP program;
apheresis platelet;
adverse reactions to blood donation
- From:
Chinese Journal of Blood Transfusion
2023;36(10):943-945
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To reduce the occurrence of adverse reactions to blood donation during platelet collection in female blood donors with low body weight and high platelet count, so as to improve the comfortableness during platelet collection and increase the proportion of repeated blood donors. 【Methods】 The control group and observation group were compared to explore the causes that may cause adverse reactions in the blood collection cycle using blood collection process program software in MCS+, and the incidence of blood donation reaction was compared and observed by increasing the times of oral administrations of calcium gluconate by 10%, increasing the number of collection cycles and reducing the peak plasma volume of the last cycle. 【Results】 After comparing the two groups, it was found that the incidence of adverse reactions in the observation group and the control group was 16.7%(3/18) and 81.2%(26/32), the proportion of repeated donors in the observation group and the control group was 77.7%(14/18) and 31.2%(10/32). 【Conclusion】 Female platelet donors with low body weight and high platelet count should be given more care during the collection process. It is suggested that giving more times of oral administrations of calcium gluconate by 10% and one more collection cycle to reduce the collection peak in each cycle, as well as the supplement of saline, which can effectively reduce the occurrence of adverse reactions to blood donation, thus improving blood donation satisfaction and increasing the proportion of repeated blood donors.
