Changes of serum iron and ferritin in regular voluntary blood donors
10.13303/j.cjbt.issn.1004-549x.2021.02.003
- VernacularTitle:固定无偿献血者血清铁和血清铁蛋白的变化研究
- Author:
Bo HE
1
;
Wei SU
1
;
Xuekai LIANG
1
;
Jian OUYANG
1
;
Yanping QI
1
;
Xiaobin HUANG
1
Author Information
1. Guangzhou Blood Center, Guangzhou 510095, China; The Key Medical Laboratory of Guangzhou, Key Laboratory of Blood Safety Research
- Publication Type:Journal Article
- Keywords:
regular blood donors;
blood donor iron deficiency;
serum ferritin;
serum iron;
iron storage
- From:
Chinese Journal of Blood Transfusion
2021;34(2):111-114
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To study the effect of regular blood donation on the serum iron (SI) and serum ferritin (SF) of regular blood donors. 【Methods】 A total of 240 blood samples (4~5 mL per person, with EDTA-2K anticoagulant) from regular voluntary blood donors in our center from January to June 2019 were randomly selected as the study group. Another 200 healthy subjects without blood donation history were randomly selected as the control group. SI was measured by Ferene method, SF by chemiluminescence method, and blood routine indexes by automatic hematology analyzer. 【Results】 The Hb, RBC count, HCT and other blood routine indexes of the study group and the control group were all in the normal range. SI (mol/L) in the study gourp and the control group was 17.13±4.36 vs 17.82±5.78(P>0.05), and SF (ng/mL) was 98.34±52.74 vs 147.52±91.52 (P<0.05). 【Conclusion】 SI and SF may decrease due to regular blood donation, which deserve close follow-up to ensure the safety of regular blood donors.
