Zika virus infection and transfusion safety
10.13303/j.cjbt.issn.1004-549x.2021.04.027
- VernacularTitle:寨卡病毒感染与输血安全
- Author:
Rongrong MU
1
;
Haiyan YE
1
;
Min XU
1
;
Silin LI
1
Author Information
1. Institute of Blood Transfusion, Chinese Academy of Medical Sciences and Peking Union Medical College, Chengdu 610052, China
- Publication Type:Journal Article
- Keywords:
Zika virus(ZIKV);
transfusion safety;
fetal microcephalia;
asymptomatic infection;
viremia
- From:
Chinese Journal of Blood Transfusion
2021;34(4):424-427
- CountryChina
- Language:Chinese
-
Abstract:
Zika virus(ZIKV) is an arbovirus transmitted mainly by mosquitoes. ZIKV infection usually causes mild self-limiting disease, and most of the infected patients only developed relatively mild symptoms which were often easily overlooked. However, serious damage of the central nervous system is observed in a few of the infected patients, and microcephaly of embryos and fetuses in pregnant women infected by ZIKV has attracted wide attention in recent years. Although there is a high proportion of asymptomatic infection and a high incidence of viremia, ZIKV has not been included in the routine pathogen screening before blood donation in China yet, and there is a risk of transmission through blood transfusion. This article briefly introduces the biological characteristics, epidemic characteristics, and pathogenic mechanisms of ZIKV,, and discusses ZIKV infection and the safety of blood transfusion.
