Efficacy of autologous platelet-rich plasma in the treatment of refractory wounds after breast cancer surgery
10.13303/j.cjbt.issn.1004-549x.2022.04.013
- VernacularTitle:自体富血小板血浆治疗乳腺癌根治术后难愈性创面效果的观察
- Author:
Man FANG
1
;
Yan ZHOU
2
;
Jing WANG
2
;
Qian LIU
1
;
Min WANG
1
Author Information
1. Department of Blood Transfusion, Southern District of the First Affiliated Hospital of University of Science and Technology of China, Hefei 230036, China
2. Wound Treatment Center, Southern District of the First Affiliated Hospital of University of Science and Technology of China, Hefei 230036, China
- Publication Type:Journal Article
- Keywords:
platelet-rich plasma;
radical breast cancer resection;
poor wound healing;
autologous blood component
- From:
Chinese Journal of Blood Transfusion
2022;35(4):408-412
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore the effect of autologous platelet-rich plasma (PRP) in the treatment of refractory wounds after radical breast cancer resection. 【Methods】 The clinical data of 8 patients with refractory wound healing after radical resection of breast cancer, who received autologous PRP treatment at the South District Wound Treatment Center from November 2020 to May 2021, were collected, including age, sex, wound location, wound area/depth, TNM staging, surgical method, postoperative pathology, chemotherapy conditions, PRP treatment, etc. Wound healing time and scar hyperplasia (vascular distribution, color, softness, thickness, itching, pain, etc.) were observed after PRP treatment. The efficacy of autologous PRP was analyzed and evaluated retrospectively based on the above data. 【Results】 The wounds of 8 patients healed smoothly, and the granulation tissue of the wound was relatively matured and completely covered by the crawling epidermis. The wound healing time was 14 to 26 (20.6±3.6) days, and all patients had not developed scar hyperplasia. 【Conclusion】 The efficacy of autologous PRP treatment of refractory wounds after radical breast cancer resection is fast and effective, and can eliminate scar hyperplasia, which is worthy of clinical promotion.
