Retrospective systematic analysis of incidence and severity of COVID-19 reinfection
10.19428/j.cnki.sjpm.2023.23237
- VernacularTitle:新型冠状病毒感染再感染发生率及重症率的回顾性系统分析
- Author:
Lei SHI
1
;
Shen XIN
1
;
Qin SUN
1
;
Yuan WANG
1
;
Danni LI
1
;
Ke LI
1
Author Information
1. Department of Medical Research， The Strategic Support Force Military Center， Beijing 100101，China
- Publication Type:Journal Article
- Keywords:
COVID-19;
reinfection;
critical reinfection
- From:
Shanghai Journal of Preventive Medicine
2023;35(11):1074-1080
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the incidence and severity of COVID-19 reinfection. MethodsWe searched relevant studies on COVID-19 reinfection， including cohort study， case report， and cross-sectional study in PubMed， Embase， CNKI and Wanfang databases. Revman5.3.0 was used for statistical analysis. ResultsA total of 52 studies in 19 countries were included. These literatures showed moderate and high quality. Furthermore， the pooled incidence of COVID-19 reinfection was estimated to be 1.9%（95%CI： 0.9%‒4.7%， P<0.01）， pooled incidence of reinfection among medical workers in hospitals and staff in nursing home was 13.8%（95%CI： 4.8%‒34.2%， P<0.01）， and pooled incidence of critical reinfection was 17.3%（95%CI： 11.5%‒25.9%， P<0.01）.Sensitivity and publication bias analysis showed that the pooled incidence was stable and no publication bias was identified. ConclusionIncidence and severity of COVID-19 reinfection are both high. Although the prevention and control policy against COVID-19 has been adjusted in China， the public should pay attention to taking protective measures to avoid the reinfection.
