Pharmaceutical practice of clinical pharmacist participation in a patient with Epstein-Barr virus encephalitis
- VernacularTitle:临床药师参与1例EB病毒性脑炎患者的药学实践
- Author:
Yan WANG
1
;
Shaohui ZHU
1
;
Jianing YANG
1
;
Xiaoshan CHEN
1
;
Minhua ZHOU
1
Author Information
1. Dept. of Pharmacy，Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine，Guangdong Foshan 528200，China
- Publication Type:Journal Article
- Keywords:
Epstein-Barr virus encephalitis;
clinical pharmacist;
pharmaceutical care
- From:
China Pharmacy
2023;34(24):3060-3063
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the role of clinical pharmacists in the treatment of a patient with Epstein-Barr （EB） virus encephalitis. METHODS Clinical pharmacist participated in drug diagnosis and therapy for a patient with EB virus encephalitis. According to the physiological characteristics of the disease and the pharmacokinetic-pharmacodynamic characteristics of antibiotics， clinical pharmacists suggested that the dose should be adjusted as ceftriaxone 2 g， q12 h+meropenem 2 g， q8 h. Based on the uncontrolled infection of the patient， pharmacists suggested that ceftriaxone should be stopped and vancomycin 1 million U and q12 h should be used as alternative therapy. According to the results of etiology， pharmacists suggested that acyclovir should be discontinued and replaced with ganciclovir 5 mg/kg， q12 h. The electrolyte disturbance of the patient may be adverse drug reactions caused by Mannitol injection， it was recommended to stop the drug. RESULTS The clinician followed the advice of the clinical pharmacists. After treatment， the patient improved and was discharged. CONCLUSIONS Clinical pharmacists can carry out pharmaceutical care for patients with EB virus encephalitis， assist physicians in optimizing the treatment plan of patients， and ensure the effectiveness and safety of drug treatment.
