Research progress in the diagnosis and treatment of neurotrophic keratitis
10.3980/j.issn.1672-5123.2024.1.13
- VernacularTitle:神经营养性角膜炎诊治的研究进展
- Author:
Cici YANG
1
;
Yuqian GENG
1
;
Yi LIU
1
Author Information
1. Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China
- Publication Type:Journal Article
- Keywords:
neurotrophic keratitis;
keratitis;
corneal epithelial defects;
trigeminal nerve;
eye examination
- From:
International Eye Science
2024;24(1):67-71
- CountryChina
- Language:Chinese
-
Abstract:
Neurotrophic keratitis(NK)is a degenerative corneal disease caused by impairment of trigeminal innervations. It can lead to spontaneous corneal epithelial defects, corneal ulceration and perforation. Early diagnosis of NK is crucial and requires accurate investigation of clinical history and thorough examination of ocular surface to determine clinical stage. Treatment for NK needs to be divided into stages according to disease severity. In addition to conventional treatments including artificial tears, blepharorrhaphy, and amniotic membrane transplantation, there are also emerging treatments such as targeted drug therapy and corneal neurotization. This article summarized the epidemiology, clinical manifestations and classification, etiology, diagnosis, differential diagnosis and treatment of NK, aiming to provide reference for the early diagnosis and treatment of NK in the future.
