Risk Factors Related to COVID-19Reinfection and Fatality During the Omicron (BA.1/BA.2) Period in Korea
10.3346/jkms.2023.38.e269
- Author:
Ju Hee LEE
1
;
Ji Hae HWANG
;
Eun Jung JANG
;
Ryu Kyung KIM
;
Kil Hun LEE
;
Seon Kyeong PARK
;
Jin GWACK
;
Young Joon PARK
Author Information
1. Division of Epidemiological Investigation Analysis, Korea Disease Control and Prevention Agency, Cheongju, Korea
- Publication Type:Original Article
- From:Journal of Korean Medical Science
2023;38(34):e269-
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background:This study aimed to investigate the deaths due to coronavirus disease 2019 (COVID-19) reinfection and related risk factors.
Methods:National cohort data were collected for a six-month period when omicron BA.1/BA.2 variant was dominant in South Korea.
Results:The long-term care facility residents (adjusted odds ratio, 3.11; 95% confidence interval [CI], 2.98–3.25) had significantly higher risk of reinfection than the general population. The risk of reinfection was significantly lower for persons with 2 or more vaccine doses compared to the unvaccinated. The risk of death was significantly higher in the reinfection group than in the primary infection group for persons in the 60–74 years age group (adjusted relative risk [aRR], 1.62; 95% CI, 1.19–2.20), and immunocompromised group (aRR, 4.56; 95% CI, 2.34–8.90).
Conclusion:In these data, vaccination history was significantly related to reduced COVID-19 reinfection and severe progression, and scheduled vaccinations were important even with a history of infection.
