1.Clinical Outcome of Endoscopic Submucosal Dissection for Papillary Type Early Gastric Cancer: A Multicenter Study
Hyun-Deok SHIN ; Ki Bae BANG ; Sun Hyung KANG ; Hee Seok MOON ; Jae Kyu SUNG ; Hyun Yong JEONG ; Dong Kyu LEE ; Ki Bae KIM ; Sun Moon KIM ; Seung Woo LEE ; Dong Soo LEE ; Young Sin CHO ; Il-Kwun CHUNG ; Ju Seok KIM
Gut and Liver 2024;18(3):426-433
Background/Aims:
Papillary adenocarcinoma is classified to differentiated-type gastric cancer and is indicated for endoscopic submucosal dissection. However, due to its rare nature, there are limited studies on it. The purpose of this study was to determine the outcome of endoscopic submucosal dissection in patients with papillary-type early gastric cancer and to find the risk factors of lymph node metastasis.
Methods:
Patients diagnosed with papillary-type early gastric cancer at eight medical centers, who underwent endoscopic submucosal dissection or surgical treatment, were retrospectively reviewed. The clinical results and long-term outcomes of post-endoscopic submucosal dissection were evaluated, and the risk factors of lymph node metastasis in the surgery group were analyzed.
Results:
One-hundred and seventy-six patients with papillary-type early gastric cancer were enrolled: 44.9% (n=79) in the surgery group and 55.1% (n=97) in the endoscopic submucosal dissection group. As a result of endoscopic submucosal dissection, the en bloc resection and curative resection rates were 91.8% and 86.6%, respectively. The procedure-related complication rate was 4.1%, and local recurrence occurred in 3.1% of patients. Submucosal invasion (odds ratio, 3.735; 95% confidence interval, 1.026 to 12.177; p=0.047) and lymphovascular invasion (odds ratio, 7.636; 95% confidence interval, 1.730 to 22.857; p=0.004) were the risk factors of lymph node metastasis in papillary-type early gastric cancer patients.
Conclusions
The clinical results of endoscopic submucosal dissection in papillary-type early gastric cancer were relatively favorable, and endoscopic submucosal dissection is considered safe if appropriate indications are confirmed by considering the risk of lymph node metastasis.
2.Inverse Psoriasis with Autoimmune Hepatitis.
Joon SEOK ; Kui Young PARK ; Hyun Woong LEE ; Hee Sung KIM ; Joo Hyun SHIM ; Seong Jun SEO ; Chang Kwun HONG
Annals of Dermatology 2017;29(6):820-821
No abstract available.
Hepatitis, Autoimmune*
;
Psoriasis*
3.The Efficacy of Coblator in Turbinoplasty.
Keun Cheol LEE ; Jeong Min CHO ; Seok Kwun KIM ; Kwang Ryeol LIM ; Sang Yun LEE ; Su Seong PARK
Archives of Craniofacial Surgery 2017;18(2):82-88
BACKGROUND: Turbinate hypertrophy is one of the common causes of chronic nasal obstruction. In principle, therapeutic guidelines recommend medical treatment. Failure to treat turbinate thickening despite drug therapy may indicate the need for surgery. The main aim of this study was to determine the effect of radiofrequency surgery, among various other surgical procedures, on people with both nasal septal deviation and turbinate hypertrophy. METHODS: Among people with nasal deviation who visited the subject hospital between July 2008 to July 2014, 21 people with nasal septal deviation and severe turbinate hypertrophy before their surgery had undergone septoplasty with turbinoplasty using radiofrequency combined with septoplasty. The degree of the turbinate's hypertrophy was appraised in all the patients before and after the surgery using the rhinoscopy, and acoustic rhinometry was objectively carried out. The subjective effect of the turbinoplasty using radiofrequency was explored through the visual analog scale (VAS) score. RESULTS: The degree of contraction of the nasal mucosa after the rhinoscopy changed from Grades 3 and 4 (100%) to Grades 1 and 2 (95.2%) and Grades 3 (4.8%). The minimal cross-sectional area significantly increased from 0.44±0.07 to 0.70±0.07 cm² (p<0.05). The nasal cavity volume increased from 4.79±0.49 to 6.76±0.55 cm² (p<0.05). The subjective symptoms evaluated with VAS score a year after the surgery significantly improved (p<0.05). CONCLUSION: Turbinoplasty using Coblator with septoplasty is an effective treatment method because it expands nasal cavity, has a low incidence of complications, subjectively improves symptoms, and has short treatment duration.
Drug Therapy
;
Humans
;
Hypertrophy
;
Incidence
;
Methods
;
Nasal Cavity
;
Nasal Mucosa
;
Nasal Obstruction
;
Rhinometry, Acoustic
;
Rhinoplasty
;
Turbinates
;
Visual Analog Scale
4.A Tender Fingertip Papule in an Elderly Woman.
Joon SEOK ; In Young OH ; Kui Young PARK ; Kapsok LI ; Beom Joon KIM ; Seong Jun SEO ; Myeung Nam KIM ; Chang Kwun HONG
Korean Journal of Dermatology 2017;55(7):477-478
5.Solitary Fibrous Tumor in Buccal Cheek Mucosa.
Chung Min YOON ; Jeong Min CHO ; Kwang Ryeol LIM ; Seok Kwun KIM ; Su Jin KIM ; Keun Cheol LEE
Archives of Craniofacial Surgery 2017;18(3):218-221
A solitary fibrous tumor is a relatively uncommon neoplasm that usually occurs in the pleura but occurs extremely rarely in the oral cavity. Reported herein is a rare case of a solitary fibrous tumor in the buccal cheek mucosa. A 50-year-old man visited the authors' hospital due to a buccal cheek mass whose size had increased. Excisional biopsy was done under local anesthesia. After the excisional biopsy, the patient was diagnosed to have a solitary fibrous tumor. In immunohistochemistry, the patient's solitary fibrous tumor was characterized by the expression of CD34 and CD99 on the neoplastic cells, and negativity for Bcl-2 and S-100. No recurrence or complication occurred for a period of 5 years. The growth of a primary solitary fibrous tumor in the buccal cheek mucosa is extremely rare and has been rarely reported in the South Korean medical literature. A solitary fibrous tumor must be distinguished from other spindle cell tumors. Presented herein is a case of primary solitary fibrous tumor in the buccal cheek mucosa. The relevant literature is briefly reviewed.
Anesthesia, Local
;
Biopsy
;
Cheek*
;
Humans
;
Immunohistochemistry
;
Middle Aged
;
Mouth
;
Mouth Mucosa
;
Mucous Membrane*
;
Pleura
;
Recurrence
;
Solitary Fibrous Tumors*
6.Clinical Study of Prevalence of Antibiotic Resistance of Escherichia coli in Urinary Tract Infection in Children: A 9-year Retrospective, Single Center Experience.
Eun Young SEO ; Seung Man CHO ; Dong Seok LEE ; Sung Min CHOI ; Doo Kwun KIM
Childhood Kidney Diseases 2017;21(2):121-127
PURPOSE: The aim of this study was to determine the prevalence of antibiotic susceptibility and resistance of Escherichia coli in urinary tract infections (UTIs) in children. METHODS: We retrospectively reviewed the clinical records of 212 inpatients aged 18 years or younger with UTIs treated at the Pediatric Department of Dongguk University Gyeongju Hospital between January 2008 and December 2016. For comparison, patients were divided into three groups according to age as follows: group 1, ≤1 month; group 2, >1 month to ≤12 months; and group 3, ≥13 months. The antibiotic resistance rates from January 2008 to December 2012 (study period 1) and from January 2013 to December 2016 (study period 2) were analyzed statistically by group. RESULTS: As the patient age increased, the antibiotic resistance rate to ampicillin (P=0.013), levofloxacin (P=0.050), piperacillin/tazobactam (TZP) (P<0.001), and trimethoprim/sulfamethoxazole (P=0.002) increased. The frequency of extended spectrum beta-lactamase producing E. coli showed a significant difference from 5 cases (4.6%) in study period 1 and 16 cases (15.8%) in study period 2 (P=0.007). The antibiotic resistance rate of E. coli was compared between the two time periods and we found that the antibiotic resistance rate to cefotaxime was significantly increased from 5.4% to 16.8% (P=0.008) and that to TZP was significantly decreased from 40.5% to 7.9% (P<0.001). CONCLUSION: Over the past 9 years, the resistance rate to cefotaxime has increased but the resistance rate to TZP has decreased. Thus, it is important to continue to investigate the antibiotic resistance rates of bacteria in the community.
Ampicillin
;
Bacteria
;
beta-Lactamases
;
Cefotaxime
;
Child*
;
Clinical Study*
;
Drug Resistance, Microbial*
;
Escherichia coli*
;
Escherichia*
;
Gyeongsangbuk-do
;
Humans
;
Inpatients
;
Levofloxacin
;
Prevalence*
;
Retrospective Studies*
;
Urinary Tract Infections*
;
Urinary Tract*
7.Clinical Study of Prevalence of Antibiotic Resistance of Escherichia coli in Urinary Tract Infection in Children: A 9-year Retrospective, Single Center Experience.
Eun Young SEO ; Seung Man CHO ; Dong Seok LEE ; Sung Min CHOI ; Doo Kwun KIM
Childhood Kidney Diseases 2017;21(2):121-127
PURPOSE: The aim of this study was to determine the prevalence of antibiotic susceptibility and resistance of Escherichia coli in urinary tract infections (UTIs) in children. METHODS: We retrospectively reviewed the clinical records of 212 inpatients aged 18 years or younger with UTIs treated at the Pediatric Department of Dongguk University Gyeongju Hospital between January 2008 and December 2016. For comparison, patients were divided into three groups according to age as follows: group 1, ≤1 month; group 2, >1 month to ≤12 months; and group 3, ≥13 months. The antibiotic resistance rates from January 2008 to December 2012 (study period 1) and from January 2013 to December 2016 (study period 2) were analyzed statistically by group. RESULTS: As the patient age increased, the antibiotic resistance rate to ampicillin (P=0.013), levofloxacin (P=0.050), piperacillin/tazobactam (TZP) (P<0.001), and trimethoprim/sulfamethoxazole (P=0.002) increased. The frequency of extended spectrum beta-lactamase producing E. coli showed a significant difference from 5 cases (4.6%) in study period 1 and 16 cases (15.8%) in study period 2 (P=0.007). The antibiotic resistance rate of E. coli was compared between the two time periods and we found that the antibiotic resistance rate to cefotaxime was significantly increased from 5.4% to 16.8% (P=0.008) and that to TZP was significantly decreased from 40.5% to 7.9% (P<0.001). CONCLUSION: Over the past 9 years, the resistance rate to cefotaxime has increased but the resistance rate to TZP has decreased. Thus, it is important to continue to investigate the antibiotic resistance rates of bacteria in the community.
Ampicillin
;
Bacteria
;
beta-Lactamases
;
Cefotaxime
;
Child*
;
Clinical Study*
;
Drug Resistance, Microbial*
;
Escherichia coli*
;
Escherichia*
;
Gyeongsangbuk-do
;
Humans
;
Inpatients
;
Levofloxacin
;
Prevalence*
;
Retrospective Studies*
;
Urinary Tract Infections*
;
Urinary Tract*
8.Is Rectosigmoid Vaginoplasty Still Useful?.
Seok Kwun KIM ; Ji Woen PARK ; Kwang Ryeol LIM ; Keun Cheol LEE
Archives of Plastic Surgery 2017;44(1):48-52
BACKGROUND: The ideal vaginoplasty must be successful functionally as well as have a natural appearance, and also must retain its functionality and appearance over the long term. Conventional vaginoplasty techniques have functional limitations and are associated with recurrent complications, but rectosigmoid vaginoplasty is known to have a high satisfaction rate due to its functional similarity with the vagina. We conducted the present study to assess the usability of rectosigmoid vaginoplasty over the course of long-term follow-up. METHODS: From March 1992 to February 2014, 84 patients were treated with rectosigmoid vaginoplasty; 44 had gender identity disorder, 29 had vaginal agenesis, 8 had female pseudohermaphroditism, and 3 had gynecologic malignancies after radical pelvic surgery. This retrospective study was based on a review of the patients' records, clinical examinations, complications, and questionnaires about appearance, function, and sexual intercourse. RESULTS: All patients who underwent rectosigmoid vaginoplasty were discharged within 2 weeks without surgical flap loss. The early complications were partial flap necrosis, difficulty in defecation, mucous hypersecretion, and postoperative ileus. The late complications were vaginal introitus contracture, vaginal prolapse, and difficulty in urination. The mean length and diameter of the neovagina 3.4 years after rectosigmoid vaginoplasty were 13.2 cm and 3.8 cm, respectively. On questionnaires about satisfaction, 70% of patients reported excellent satisfaction, 11% good, 12% fair, and 7% poor. CONCLUSIONS: Rectosigmoid vaginoplasty is useful, safe, and well-accepted operative method with good functional and cosmetic results, such as natural lubrication and adequate vaginal length and width obtained without requiring the use of a dilator.
46, XX Disorders of Sex Development
;
Coitus
;
Contracture
;
Defecation
;
Follow-Up Studies
;
Gender Identity
;
Humans
;
Ileus
;
Lubrication
;
Methods
;
Necrosis
;
Retrospective Studies
;
Surgical Flaps
;
Urination
;
Uterine Prolapse
;
Vagina
9.Single Vesicular Papule on the Eyelid with Atypical Histopathology Findings.
Moo Yeol HYUN ; Joon SEOK ; Kui Young PARK ; Beom Joon KIM ; Seong Jun SEO ; Chang Kwun HONG
Annals of Dermatology 2016;28(1):140-141
No abstract available.
Eyelids*
10.A Case of Facial Sarcoptes scabiei in a Female Child.
Joon SEOK ; Kui Young PARK ; Kapsok LI ; Beom Joon KIM ; Seong Jun SEO ; Myeung Nam KIM ; Chang Kwun HONG
Annals of Dermatology 2016;28(4):505-506
No abstract available.
Child*
;
Female*
;
Humans
;
Sarcoptes scabiei*

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