1.The analysis of the provider, payer, and regulator stakeholders' understanding and acceptance of the Universal Healthcare Law in three provinces in the Philippines: A qualitative study using a content analysis approach.
Edwin M. Mercado ; Hannah N. Gilbert ; Jose V. Tecson III ; Chunling Lu
Acta Medica Philippina 2026;60(1):7-21
BACKGROUND AND OBJECTIVE
In 2018, the Philippine Congress passed the Universal Healthcare (UHC) Law and its implementing rules which mandated the enrollment of all Filipinos to PhilHealth, the national social health insurance corporation. The Department of Health (DOH) and PhilHealth will leverage their strategic purchasing power by affiliating Health Care Provider Networks (HCPNs), established within the geopolitical boundaries of a province or a highly urbanized city, through service level agreements. This study aims to shed light on what is expected from providers, payers, and regulators to implement UHC successfully.
METHODSThe researchers conducted an inductive, content analytic qualitative study guided by the World Health Organization’s (WHO) Building Blocks Framework to determine the understanding and acceptance of the implementing rules of the UHC Law and the perceived barriers and enablers from the provider, payer, and regulator stakeholders in three provinces in the Philippines. Purposive sampling was utilized to provide the best representation across different economic and physical settings. A content analysis was done through an inductive process of coding concepts, which was the basis for categories grouped and matched deductively with the WHO framework. This formed the broader sub-themes and were used for the final data interpretation.
RESULTSA total of 16 focus group discussions (FGDs) and nine in-depth interviews (IDIs) were performed with 84 participants. Inductive thematic analysis of categories and subcategories showed that the participants support the goals and objectives of the UHC Law. Still, perceived barriers refer to the lack of and improper use of funds, the need to clarify the implementing guidelines, and the role of politics. The participants indicated that solidarity and social connectedness with health system adaptability and resilience are enablers for the success of UHC reforms.
CONCLUSIONProposals to mitigate the barriers include expanding the funding source, clarifying rules on the f inancial management system, and providing guidelines on health delivery integration to ensure access to patient care. Decentralization with autonomy will allow the stakeholders to align health programs with local needs. Proper representation in decision-making bodies is desirable to establish strong community involvement and solidarity. Resilience and adaptability based on a feedback loop are imperative.
Human ; Universal Health Care ; Health Financing ; Healthcare Financing ; Philippines
2.Mental health literacy among young and adult population in the Caraga Region, Philippines.
Hannah Dara V. Garay-Nugroho ; Tina Joy G. Mante ; Maffi A. Titoy ; Pedrito V. Famorcan III ; Dinnes Karl N. Garcia
Acta Medica Philippina 2026;60(4):62-70
BACKGROUND
Mental health literacy (MHL) is an important mental health strategy since it contributes to early detection, enhances help-seeking behavior, and reduces stigma and discrimination against people with mental disorders.
OBJECTIVEThe objectives of the present study were to assess the level of mental health literacy and its correlation, and to examine the predictive effect of demographic profiles on mental health literacy among young and adult populations in the five cities of Caraga, using a standardized mental health literacy scale in 2023.
METHODSThis study applied a cross-sectional survey. It surveyed 729 individuals from five cities in Caraga using the Mental Health Literacy Scale from Dias et al. Descriptive analysis, such as frequency, percentage, mean, and standard deviation, and inferential statistics, such as Pearson correlation, independent t-test, and multi-linear regression, were used for data analysis.
RESULTSThe mental health literacy of the young and adult populations can be classified as adequate or good. Zooming in on details, the respondents have a very good understanding of help-seeking behavior and self-strategies but only a good understanding of knowledge and beliefs/attitudes. Pearson’s correlation analysis revealed a significant positive relationship between knowledge, erroneous beliefs, self-strategies, and help-seeking behavior (p < 0.001). In addition, Independent t-test and ANOVA revealed significant differences in sex, family income, employment, civil status, educational level, and age group (p < 0.01). A multiple linear regression indicated that demographic profile predictors were found to be statistically significant, and positively with mental health literacy, with education and family income as the strongest predictors.
CONCLUSIONThe present study concluded that the young and adult populations in the five cities in Caraga have adequate literacy on mental health, encompassing knowledge, beliefs, self-strategies, and help-seeking behaviors. The increases in knowledge, belief, and self-strategies are associated with their higher level of help-seeking; in addition, the demographic profiles (e.g., sex, age, education, monthly income, and employment) have implications on young and adults’ mental health literacy in the five cities in Caraga. The result may not be generalizable beyond the studied region or demographic. In addition, it recommended that mental health literacy programs prioritize individuals with lower levels of education and family income as these factors Xwere found to have the most significant influence.
Human ; Mental Health
3.Agarwood's Role in Inflammatory-related Conditions: A Systematic Review of Animal Models
Hashim YZH-Y ; Abbas P ; Samsudin N ; I.R Gill C
The International Medical Journal Malaysia 2026;25(No. 1):16-29
Agarwood (Aquilaria spp.) is a resinous wood traditionally used in various medicinal
systems across Asia for treating inflammation-related ailments. Despite its
longstanding ethnopharmacological use, scientific validation of its anti-inflammatory
effects remains fragmented. This scoping review aims to systematically evaluate and
synthesize current evidence from animal studies investigating the anti-inflammatory
potential of agarwood. A comprehensive literature search was conducted using
PubMed, Scopus, and Web of Science. Inclusion criteria focused on original animal
studies assessing the anti-inflammatory effects of agarwood extracts, essential oils,
or derivatives. Data on study design, animal models, agarwood species, treatment
dosage, duration, biomarkers, and outcomes were extracted and summarized
narratively due to methodological heterogeneity. Eight studies met inclusion criteria,
involving models of inflammation-related conditions such as pain, neuroinflammation,
gastrointestinal injury, cancer, and toxicity. Agarwood treatment consistently reduced
pro-inflammatory cytokines (e.g., IL-1β, IL-6, TNF-α), modulated oxidative stress
markers (e.g., NO, SOD, GSH), and regulated signalling pathways including NF-κB,
p38 MAPK, and Nrf2–ARE. Notably, improvements were observed in behavioural
and histological outcomes across models, with evidence of dose-dependent effects
in several studies. In conclusion, preclinical evidence supports agarwood’s broadspectrum anti-inflammatory and antioxidant properties across multiple organ
systems. These findings provide mechanistic insights and a scientific basis for its
traditional use. However, variability in species, extraction methods, and study designs
highlights the need for standardised protocols and clinical validation to advance
agarwood as a potential therapeutic agent.
4.Assessment of out-of-pocket expenditure of HER2-positive breast cancer patients in a tertiary cancer center and private clinics in the Philippines.
Karen Anjela M. MONDRAGON ; Rich Ericson C. KING ; Lance Isidore G. CATEDRAL ; Frederic Ivan L. TING ; Rogelio N. VELASCO ; Aylmer Rex B. HERNANDEZ ; Irisyl Orolfo REAL ; Lia M. PALILEO-VILLANUEVA
Acta Medica Philippina 2026;60(8):7-22
BACKGROUND
The survival advantage of HER2-positive breast cancer from targeted treatment is commonly undermined by catastrophic health expenditure (CHE), particularly in resource-limited areas. Recognizing that financial catastrophe leads to non-adherence to treatment and dissaving practices, we examined the out-of-pocket (OOP) expenses of patients with HER2-positive breast cancer.
OBJECTIVEThe study aimed to estimate the median total per-cycle out-of-pocket expenditure of HER2-positive breast cancer treatment from the patient perspective, in public and private clinics, evaluate the association of catastrophic health expenditure with non-adherence to treatment, and describe dissaving practices.
METHODSThis was a cross-sectional micro-costing analysis of the treatment of HER2-positive breast cancer from the patient perspective from a tertiary cancer center and select private clinics in the Philippines. Random sampling of patients with HER2-positive breast cancer was done. Using a validated questionnaire, a guided interview was administered. Catastrophic health expenditure was estimated as having OOP of >20% of the household income. OOP costs were assessed retrospectively from the time of confirmed HER2 diagnosis up to the date of survey, while household income referred to the corresponding period. The proportion of patients experiencing catastrophic health expenditure was computed. Fisher's exact was used to assess for any association between CHE and non-adherence to treatment. Descriptive statistics were used to report dissaving practices. All statistical analyses were performed using Stata analytical software version 12.
RESULTSA total of 101 patients participated in the study. The mean age of participants from the tertiary cancer center and private clinics were 52 and 58 years old respectively. Patients from the private clinics had a median total OOP expenditure of PhP 54,737.06 (IQR = PhP 102,670.00), compared with patients from tertiary cancer center who had a median total OOP expenditure of PhP 13,920.66 (IQR = PhP 20,830.00). The overall prevalence of CHE (90.9%, 95% CI 0.81, 0.95) and nonadherence to treatment with trastuzumab (79%, 95% CI 0.70, 0.87) were high, and similar in both groups. A number of dissaving practices such as resignation from work, borrowing money from friends, selling assets were observed.
CONCLUSIONThe high rate of CHE and treatment delay among patients with HER2-positive breast cancer were not addressed by the existing cancer programs. Most OOP expenditure was for trastuzumab. Current cancer support programs have potential to address the financial impact of their treatment.
Human ; Therapeutics ; Survival ; Patients ; Neoplasms ; Philippines ; Health Expenditures ; Breast Neoplasms
5.The correlation between quality of life (QOL) and medication adherence to antihypertensive medications among middle-aged Filipino adults.
Aiella Antonia B. RECTO ; Alexandria H. REQUIERME ; Katrina Nicole D. REQUIZO ; Armando Miguel I. REYES ; Dean Adrian G. REYES ; John Andrew N. REYES ; Marcellus Francis L. RAMIREZ
Journal of Medicine University of Santo Tomas 2026;10(1):1837-*1847
INTRODUCTION
Hypertension is a serious public health issue that puts individuals at risk for various morbidity and mortality indicators. One of the most crucial factors in managing blood pressure and preventing complications is medication adherence which is linked to several determinants. This study explored the correlation between medication adherence among middle-aged hypertensive adults and the different domains of quality of life (QOL), which includes physical, psychological, social relationship and environment.
METHODSThis cross-sectional study involved 96 Filipino residents of Brgy. San Jose, Navotas City aged 35 to 65 years old diagnosed with hypertension and prescribed anti-hypertensive medications. Pearson’s correlation coefficient was used to calculate the correlation between different domains of QOL as well as the overall QOL score.
RESULTSResults revealed a statistically significant but weak positive correlation between overall QOL and medication adherence (r = 0.336, pCONCLUSION
The study demonstrates that while medication adherence is modestly associated with better perceived QOL, especially in physical, psychological and environmental aspects, other factors likely influence both outcomes. These findings highlight the need for holistic, community-based interventions that address not only medication adherence but also environmental and psychosocial barriers to care in managing hypertension.
Human ; Adult: 25-44 Yrs Old ; Middle Aged: 45-64 Yrs Old ; Aged: 65-79 Yrs Old ; Quality Of Life ; Public Health ; Medication Adherence ; Antihypertensive Agents ; Blood Pressure ; Interpersonal Relations
6.Determinants of age at adiposity rebound in Filipino pediatric outpatients of a University Hospital.
Emmanuel F. BARAQUEL ; Bernard Emil N. BARRERA ; Danica Louice S. BASILIO ; Aleeza Casey S. BATARA ; Serena Mey M. BAUTISTA ; Sean Kenneth N. BANTING ; Charles Dominic BARRIGA ; Eljon Valen C. BANIQUED ; Marichu J. DE CHAVEZ ; Leilani B. MERCADO-ASIS
Journal of Medicine University of Santo Tomas 2026;10(1):1848-1861
OBJECTIVES
Adiposity rebound (AR), the childhood period at which body mass index (BMI) rises from its lowest point, is linked to increased risk of later obesity. The study aims to determine the average age at AR, describe baseline characteristics and analyze the correlation between these characteristics and timing of AR in a population of Filipino pediatric outpatients.
DESIGNSeven subjects born between 2016 and 2019 from a University Hospital Outpatient Department participated in this cross-sectional analytic study. Childhood anthropometrics were retrospectively collected to determine the age at AR by plot visual inspection. Sex, birth weight and gestational age were obtained from hospital records; breastfeeding duration, maternal BMI, parental obesity, maternal age, maternal smoking, education, parity and family income were gathered through a questionnaire completed by mothers or guardians. Associations were assessed using bootstrap univariate linear regression.
RESULTSThe mean age at AR was 3.2 years (SD = 1.2). Vaginal delivery was significantly associated with later age at AR compared to cesarean section (p = 0.035). Socioeconomic status at ages 2 to 5 showed positive association with delayed AR. Higher monthly family income (≥₱19,000) at ages 2 to 5 years was significantly associated with delayed age at AR. Other baseline childhood and parental factors showed no significant correlation with age at AR.
CONCLUSIONThese results highlight the complex and context-dependent nature of AR, emphasizing the need for further studies to better understand and mitigate early obesity risk in Filipino children.
Human ; Young Adult: 19-24 Yrs Old ; Universities ; Regression (psychology) ; Hospital Records ; Gestational Age ; Body Mass Index ; Obesity, Maternal
7.Translation and validation of the health-related quality of life in stroke patients - 26 (HRQoLISP-26) scale into Filipino for Filipino adult stroke Patients.
Shanelle Katrina N. TAN ; Portia Margarita D. SIMSUANGCO ; Fatima Mae S. SINGSON ; Joselle T. SINSON ; Celina Therese R. SOLOMON ; Arnold Christopher P. SORIANO ; Stephen Lorenzo P. SULAY ; Mikhael Thaddeus S. SUPE ; Rafael Alfonso S. SYFU ; Althea Jannary C. TALENS ; Ian Cedric D. TAN ; Jan Tyrone CABRERA ; Wennielyn F. FAJILAN ; Elenita MENDOZA ; John Dale TROGO
Journal of Medicine University of Santo Tomas 2026;10(1):1895-1903
INRODUCTION
Stroke is one of the top five leading causes of disability in the Philippines. It has a significant impact on the quality of life (QoL) of patients, particularly in the functional and psycho-emotional aspects. Thus, it is important to understand the health-related quality of life in stroke patients (HRQoLISP), which focuses on the clinical impact of the disease and disability. The assessment of a stroke patient’s QoL is prognostically significant as it can predict a patient’s treatment success and survival.
OBJECTIVEThis study aims to translate the HRQoLISP-26 into Filipino and assess its content validity for Filipino adult stroke patients.
METHODOLOGYThe HRQoLISP-26 was translated into Filipino using a forward translation protocol and an expert analyzed the forward translation. Selected expert committee members reviewed the first version to assess for content validity and the questionnaire was modified accordingly. The content validity index (CVI) was used for content validity.
RESULTSMajority of the revisions made were done to improve the semantic and grammatical accuracy of items in the Filipino version of the HRQoLISP-26. Only a few items had no revisions implemented. No revisions were done in the final version of the translated questionnaire as each item had a CVI of 1 indicating that it has good content validity.
CONCLUSIONThe Filipino translated HRQoLISP-26 questionnaire is a validated questionnaire that allows assessment of a stroke survivor’s QoL.
Quality Of Life ; Patients ; Life ; Health ; Adult ; Stroke
8.Assessment of out-of-pocket expenditure of HER2-positive breast cancer patients in a tertiary cancer center and private clinics in the Philippines.
Karen Anjela M. MONDRAGON ; Rich Ericson C. KING ; Lance Isidore G. CATEDRAL ; Frederic Ivan L. TING ; Rogelio N. VELASCO ; Aylmer Rex B. HERNANDEZ ; Irisyl Orolfo REAL ; Lia M. PALILEO-VILLANUEVA
Acta Medica Philippina 2026;60(8):7-22
BACKGROUND
The survival advantage of HER2-positive breast cancer from targeted treatment is commonly undermined by catastrophic health expenditure (CHE), particularly in resource-limited areas. Recognizing that financial catastrophe leads to non-adherence to treatment and dissaving practices, we examined the out-of-pocket (OOP) expenses of patients with HER2-positive breast cancer.
OBJECTIVEThe study aimed to estimate the median total per-cycle out-of-pocket expenditure of HER2-positive breast cancer treatment from the patient perspective, in public and private clinics, evaluate the association of catastrophic health expenditure with non-adherence to treatment, and describe dissaving practices.
METHODSThis was a cross-sectional micro-costing analysis of the treatment of HER2-positive breast cancer from the patient perspective from a tertiary cancer center and select private clinics in the Philippines. Random sampling of patients with HER2-positive breast cancer was done. Using a validated questionnaire, a guided interview was administered. Catastrophic health expenditure was estimated as having OOP of >20% of the household income. OOP costs were assessed retrospectively from the time of confirmed HER2 diagnosis up to the date of survey, while household income referred to the corresponding period. The proportion of patients experiencing catastrophic health expenditure was computed. Fisher's exact was used to assess for any association between CHE and non-adherence to treatment. Descriptive statistics were used to report dissaving practices. All statistical analyses were performed using Stata analytical software version 12.
RESULTSA total of 101 patients participated in the study. The mean age of participants from the tertiary cancer center and private clinics were 52 and 58 years old respectively. Patients from the private clinics had a median total OOP expenditure of PhP 54,737.06 (IQR = PhP 102,670.00), compared with patients from tertiary cancer center who had a median total OOP expenditure of PhP 13,920.66 (IQR = PhP 20,830.00). The overall prevalence of CHE (90.9%, 95% CI 0.81, 0.95) and nonadherence to treatment with trastuzumab (79%, 95% CI 0.70, 0.87) were high, and similar in both groups. A number of dissaving practices such as resignation from work, borrowing money from friends, selling assets were observed.
CONCLUSIONThe high rate of CHE and treatment delay among patients with HER2-positive breast cancer were not addressed by the existing cancer programs. Most OOP expenditure was for trastuzumab. Current cancer support programs have potential to address the financial impact of their treatment.
Human ; Therapeutics ; Survival ; Patients ; Neoplasms ; Philippines ; Health Expenditures ; Breast Neoplasms
9.Relationship of Filipino MSUD children’s nutrient intake, nutritional status, and leucine level and caregiver's nutrition knowledge, attitudes, and practices.
Marife D. Sevilla ; Cecile Leah T. Bayaga ; Maria Sofia V. Amarra ; Ebner Bon G. Maceda ; Francisco N. De Los Reyes ; Leniza de Castro-Hamoy
Acta Medica Philippina 2026;60(5):92-108
BACKGROUND AND OBJECTIVES
Diet compliance is critical in managing Maple Syrup Urine Disease (MSUD) to prevent physiological and neurological damage. However, there is a lack of studies looking at factors critical to diet compliance. This study determined the caregivers’ nutrition knowledge, attitudes, and feeding practices (KAP); and its relationship to Filipino MSUD children’s leucine level, nutritional status, and nutrient intake.
METHODSA cross-sectional, sequential explanatory research approach using survey was utilized. Data tools were questionnaires and food records.
RESULTSThe participants were 20 caregivers and 21 MSUD children (aged 6 to 83 months). Caregivers had moderately high feeding practices and knowledge scores and had positive attitudes towards providing adequate nutritional care; still, they were struggling with diet compliance.
Their nutrition knowledge was related to their attitude (p-value: 0.021), feeding practices (p-value: 0.037), and their children’s weight-for-age (p-value: 0.036). Furthermore, knowledge and feeding practices were related to the children’s natural-protein status (p-value: 0.043 and 0.006, respectively). The caregivers’ sex was related to the children’s leucine (p-value=0.010), those with female caregivers had lower leucine by 470 μmol/L on average. Moreover, children with good leucine control belonged to higher-income households (p-value=0.049).
CONCLUSIONWith caregiver's nutrition knowledge having been possibly associated with the children’s weight-forage, and their knowledge and feeding practices with the children's natural protein status, as well as knowledge positively affecting both attitude and feeding practice, interventions for improving all caregivers’ nutrition knowledge and feeding practices are recommended. Additionally, with caregivers’ sex and income having been found to be related to metabolic control, it is suggested that strategies to better manage these barriers be carried out. These may include improving support for male caregivers, with children under their care having higher leucine than those cared for by their female counterparts. Added provisions may likewise be planned for further reducing the impact of income-related barriers.
Human ; Caregivers ; Attitude ; Maple Syrup Urine Disease ; Child ; Children
10.Participatory action research in health promotion in the Philippines: A scoping review.
Ferlie Rose Ann N. Famaloan ; Kristine C. Alvina ; Lynnell Alexie D. Ong ; Carl Abelardo T. Antonio ; Katherine Ann V. Reyes
Acta Medica Philippina 2026;60(5):109-124
BACKGROUND AND OBJECTIVES
Health promotion necessitates a multifaceted approach, focusing on individual, social, and environmental factors. Participatory Action Research (PAR) offers a process for community-level knowledge to inform these approaches, but little is known about its actual utilization. This review was conducted to explore the implementation and effectiveness of PAR in health promotion in the Philippine context. The specific objectives are: 1) to systematically map and analyze the existing literature on PAR in health promotion within the Philippine context; 2) to identify and categorize the levels of community participation in PAR initiatives; and 3) to evaluate the spheres of influence of health equity principles in PAR methodologies in health promotion.
METHODSA scoping review was implemented following the protocol by Mak and Thomas (2022), guided by the Health Equity Framework and the New Economics Foundation's Ladder of Participation, highlighting the empowerment and participation of communities in health research to produce relevant and sustainable outcomes. PubMed, HERDIN, and Google Scholar were searched to gather a comprehensive range of literature, then analyzed for themes relating to community engagement in health promotion through PAR.
RESULTSA total of 452 articles were obtained from the initial search. After applying inclusion and exclusion criteria, 12 articles were included for analysis. The results highlighted the importance of engaging community leaders and advocacy groups as entry points in engaging community members, which were seen to be more effective in collaborating with the community. PAR was able to effectively identify gaps in health systems, particularly in access to programs for vulnerable sectors. The studies also exhibited differing levels of participation of the researchers with diverse population groups. This diversity in participant engagement led to more tailored and community specific interventions, fostering social innovation and better community well-being.
CONCLUSIONThe integration of PAR in health promotion demonstrates a robust approach to addressing health inequities, showcasing the potential for community driven research to foster equitable health outcomes. PAR enabled communities to lead and shape interventions, making them more relevant and effective. The spectrum of participatory activities reveals the diversity of PAR as a research approach, and an opportunity to develop guidelines on what constitutes PAR in the global context. This approach is crucial in developing sustainable health strategies that are responsive to the needs of diverse communities, ultimately contributing to the global discourse on community-driven health promotion and equity.
Health Promotion ; Research ; Philippines


Result Analysis
Print
Save
E-mail