1.Axial biomechanical performance evaluation of locally-developed modular external fixator.
Jan Francois B. Severo ; Miguel Sandino O. Aljibe ; Anjenina U. Durana ; Jason Pechardo ; Dionella Jitka B. Quinagoran ; Eduardo R. Magdaluyo Jr. ; Emmanuel P. Estrella
Acta Medica Philippina 2026;60(9):25-32
BACKGROUND
In the Philippines and other developing countries, access to high-stability external fixators for traumainduced bone fracture management is limited, as modular external fixators, especially those with snap-on features, are manufactured overseas and are prohibitively expensive for most Filipino patients.
OBJECTIVEThis study aimed to assess the biomechanical performance of a locally-developed modular external fixator prototype for tibial diaphyseal fractures in comparison to available external fixators, such as Roger Anderson and Hoffmann. This provides an initial evaluation for the use of the external fixator as an alternative in terms of its stability.
METHODSUsing axial compression testing compliant with the ASTM F1541-24 standards, the ultimate strength, yield strength, safe strength, and stiffness were measured across various fixator types and tightening mechanisms, with or without the aid of a wrench. Statistical tools such as the t-test assuming equal variances, one-way analysis of variance, and Tukey-Kramer test with a 0.05 level of significance were used to determine any significant differences.
RESULTSThe mechanical performance of the external fixator prototype increased by a factor of 1.5 to 2.5 after the clamps were tightened with the wrench. However, when hand-tightened, it still performed sufficiently, showing a comparable mechanical performance with the Roger Anderson Fixator. In terms of the ultimate, safe, and yield strengths, it performed competitively in comparison with the Hoffmann system. However, there is a significant difference in stiffness between the prototype and the Hoffmann system.
CONCLUSIONThe locally-developed external fixator was comparable biomechanically to the commercially available external fixators and the prototypes in different studies.
Evaluation Studies As Topic ; Developing Countries ; External Fixators ; Fractures, Bone ; Philippines ; Patients
2.Recurrent sporadic parathyroid carcinoma in a 29-year-old Filipino female presenting with primary hyperparathyroidism: A case report and literature review.
Eldimson BERMUDO ; Jose Vicente BORJA II ; Al-zamzam ABUBAKAR
Philippine Journal of Pathology 2026;11(1):63-69
Parathyroid carcinoma is a rare endocrine malignancy with an indolent course but a high risk of recurrence. Diagnosis remains challenging, requiring integration of clinical, biochemical, radiologic, and histopathologic findings. We report a young patient presenting with primary hyperparathyroidism complicated by multiple pathologic fractures and chronic renal failure. Despite initial surgical and medical management, late aggressive recurrence occurred, resulting in significant systemic complications. This case highlights the need for vigilant long-term surveillance and improved diagnostic and therapeutic strategies.
Human ; Parathyroid Neoplasms ; Hyperparathyroidism ; Fractures, Spontaneous ; Philippines
3.Pituitary Stalk Interruption Syndrome Diagnosed in the Fourth Decade: A Rare Cause of Pathological Fracture in Adulthood
Muhammad Atif Sadiqqi bin Nor Azlan ; Amalina Haydar Ali Tajuddin
Journal of the ASEAN Federation of Endocrine Societies 2026;41(S1):86-
Introduction:
Pituitary stalk interruption syndrome (PSIS) is a rare
congenital disorder characterized by the neuroradiological
triad of an absent or interrupted pituitary stalk, ectopic
posterior pituitary, and anterior pituitary hypoplasia.
It is typically diagnosed in infancy or childhood due to
growth failure or delayed puberty. Diagnosis in adulthood
is uncommon and may occur after decades of untreated
hypopituitarism.
Case:
A 34-year-old Malay male with underlying physical and
intellectual disability presented after a mechanical fall
resulting in left slipped capital femoral epiphysis, an unusual
pathological fracture in adulthood. Clinical examination
revealed marked infantilism with complete absence of
secondary sexual characteristics (Tanner stage I). Laboratory
evaluation demonstrated combined pituitary hormone
deficiency, including severe central hypothyroidism,
profound hypogonadotropic hypogonadism, and central
adrenal insufficiency. Growth hormone and insulin-like
growth factor 1 were undetectable, while prolactin was
mildly elevated, consistent with pituitary stalk disruption
due to loss of hypothalamic dopaminergic inhibition. Bone
age assessment showed severe delay, corresponding to 15
years. Pituitary magnetic resonance imaging demonstrated
the classical PSIS triad: anterior pituitary hypoplasia with
partial empty sella, a high T1 signal nodule at the median
eminence representing ectopic posterior pituitary, and
non-visualization of the infundibulum, consistent with an
absent pituitary stalk. Birth history revealed premature
breech delivery, a recognized perinatal risk factor. The
patient was commenced on hormone replacement therapy,
including levothyroxine, hydrocortisone, testosterone
undecanoate, and calcium–vitamin D supplementation.
Conclusion
This case illustrates that PSIS may remain undiagnosed into
adulthood, leading to severe consequences of long-standing
hypopituitarism such as osteoporosis and pathological fractures. Clinicians should consider hypopituitarism in
adults presenting with unexplained fractures and delayed
sexual maturation, particularly when supported by a
suggestive perinatal history.
Fractures, Spontaneous
;
Pituitary Gland
4.The epidemiology and distribution of hand fractures in Singapore.
Jin Xi LIM ; Lan Anh Thi LE ; Jared Ze Yang YEH ; Jia Jun Justin BOEY ; Vaikunthan RAJARATNAM
Singapore medical journal 2025;66(9):476-480
INTRODUCTION:
The aim of this study was to elucidate the epidemiology and distribution of hand fractures in Singapore.
METHODS:
A total of 701 hand fractures in 596 patients aged 21 years and above from a single centre were reviewed from 2010 to 2011. Details regarding the patient demographics, occupation, mechanism of injury, associated injuries and treatment were obtained.
RESULTS:
Hand fractures were particularly significant in patients between the ages of 21 and 40 years 58.9% of the total cases. The relative risk of hand fractures in males was 5.5 times greater than that in females. The majority of hand fractures occurred at the workplace (47.7%), with crush injury being the main mechanism of injury (33.6%). The most common locations of hand fracture were the little finger ray (31.2%) and distal phalanges (37.7%). There were 170 cases that underwent surgical fixation, which accounted for 24.3% of all fractures. Fixation rate was similar for both closed and open fractures but was significantly higher in the proximal and middle phalanges compared to the distal phalanx and metacarpal ( P < 0.001). With regards to surgical fixation methods, wires were commonly used in either tuft fractures (100.0%) or intra-articular fractures (69.9%), whereas plates and screws were commonly used in shaft fractures (65.5%).
CONCLUSION
The most significant population that sustained hand fractures in Singapore are young to middle-aged males who are skilled manual workers. The most commonly involved ray and location of hand fractures are the little finger ray and the distal phalanges, respectively, as they are in a relatively more exposed location.
Humans
;
Singapore/epidemiology*
;
Male
;
Female
;
Adult
;
Middle Aged
;
Fractures, Bone/surgery*
;
Hand Injuries/surgery*
;
Young Adult
;
Aged
;
Hand Bones/injuries*
;
Retrospective Studies
;
Fracture Fixation, Internal
5.Deploying artificial intelligence in the detection of adult appendicular and pelvic fractures in the Singapore emergency department after hours: efficacy, cost savings and non-monetary benefits.
John Jian Xian QUEK ; Oliver James NICKALLS ; Bak Siew Steven WONG ; Min On TAN
Singapore medical journal 2025;66(4):202-207
INTRODUCTION:
Radiology plays an integral role in fracture detection in the emergency department (ED). After hours, when there are fewer reporting radiologists, most radiographs are interpreted by ED physicians. A minority of these interpretations may miss diagnoses, which later require the callback of patients for further management. Artificial intelligence (AI) has been viewed as a potential solution to augment the shortage of radiologists after hours. We explored the efficacy of an AI solution in the detection of appendicular and pelvic fractures for adult radiographs performed after hours at a general hospital ED in Singapore, and estimated the potential monetary and non-monetary benefits.
METHODS:
One hundred and fifty anonymised abnormal radiographs were retrospectively collected and fed through an AI fracture detection solution. The radiographs were re-read by two radiologist reviewers and their consensus was established as the reference standard. Cases were stratified based on the concordance between the AI solution and the reviewers' findings. Discordant cases were further analysed based on the nature of the discrepancy into overcall and undercall subgroups. Statistical analysis was performed to evaluate the accuracy, sensitivity and inter-rater reliability of the AI solution.
RESULTS:
Ninety-two examinations were included in the final study radiograph set. The AI solution had a sensitivity of 98.9%, an accuracy of 85.9% and an almost perfect agreement with the reference standard.
CONCLUSION
An AI fracture detection solution has similar sensitivity to human radiologists in the detection of fractures on ED appendicular and pelvic radiographs. Its implementation offers significant potential measurable cost, manpower and time savings.
Humans
;
Singapore
;
Emergency Service, Hospital
;
Fractures, Bone/diagnostic imaging*
;
Artificial Intelligence
;
Retrospective Studies
;
Adult
;
Male
;
Female
;
Cost Savings
;
Middle Aged
;
Pelvic Bones/diagnostic imaging*
;
Reproducibility of Results
;
Aged
;
Sensitivity and Specificity
;
Radiography
6.Expert consensus on the diagnosis and treatment of cemental tear.
Ye LIANG ; Hongrui LIU ; Chengjia XIE ; Yang YU ; Jinlong SHAO ; Chunxu LV ; Wenyan KANG ; Fuhua YAN ; Yaping PAN ; Faming CHEN ; Yan XU ; Zuomin WANG ; Yao SUN ; Ang LI ; Lili CHEN ; Qingxian LUAN ; Chuanjiang ZHAO ; Zhengguo CAO ; Yi LIU ; Jiang SUN ; Zhongchen SONG ; Lei ZHAO ; Li LIN ; Peihui DING ; Weilian SUN ; Jun WANG ; Jiang LIN ; Guangxun ZHU ; Qi ZHANG ; Lijun LUO ; Jiayin DENG ; Yihuai PAN ; Jin ZHAO ; Aimei SONG ; Hongmei GUO ; Jin ZHANG ; Pingping CUI ; Song GE ; Rui ZHANG ; Xiuyun REN ; Shengbin HUANG ; Xi WEI ; Lihong QIU ; Jing DENG ; Keqing PAN ; Dandan MA ; Hongyu ZHAO ; Dong CHEN ; Liangjun ZHONG ; Gang DING ; Wu CHEN ; Quanchen XU ; Xiaoyu SUN ; Lingqian DU ; Ling LI ; Yijia WANG ; Xiaoyuan LI ; Qiang CHEN ; Hui WANG ; Zheng ZHANG ; Mengmeng LIU ; Chengfei ZHANG ; Xuedong ZHOU ; Shaohua GE
International Journal of Oral Science 2025;17(1):61-61
Cemental tear is a rare and indetectable condition unless obvious clinical signs present with the involvement of surrounding periodontal and periapical tissues. Due to its clinical manifestations similar to common dental issues, such as vertical root fracture, primary endodontic diseases, and periodontal diseases, as well as the low awareness of cemental tear for clinicians, misdiagnosis often occurs. The critical principle for cemental tear treatment is to remove torn fragments, and overlooking fragments leads to futile therapy, which could deteriorate the conditions of the affected teeth. Therefore, accurate diagnosis and subsequent appropriate interventions are vital for managing cemental tear. Novel diagnostic tools, including cone-beam computed tomography (CBCT), microscopes, and enamel matrix derivatives, have improved early detection and management, enhancing tooth retention. The implementation of standardized diagnostic criteria and treatment protocols, combined with improved clinical awareness among dental professionals, serves to mitigate risks of diagnostic errors and suboptimal therapeutic interventions. This expert consensus reviewed the epidemiology, pathogenesis, potential predisposing factors, clinical manifestations, diagnosis, differential diagnosis, treatment, and prognosis of cemental tear, aiming to provide a clinical guideline and facilitate clinicians to have a better understanding of cemental tear.
Humans
;
Dental Cementum/injuries*
;
Consensus
;
Diagnosis, Differential
;
Cone-Beam Computed Tomography
;
Tooth Fractures/therapy*
7.Biomechanical analysis of three kinds of rigid internal fixation methods for condylar head fractures.
Junhui SUN ; Duoduo LAN ; Dong WANG ; Yao XU ; Zeyu WANG ; Chenchen ZHANG ; Kai ZHANG ; Tao XU
West China Journal of Stomatology 2025;43(1):126-132
OBJECTIVES:
This study aims to analyze the biomechanics of three kinds of rigid internal fixation methods for condylar head fractures.
METHODS:
A three dimensional finite element model of the normal mandible was constructed. It was then used to prepare condylar head fracture finite element model and three kinds of rigid internal fixation finite element model (unilateral tension screw, bilateral tension screw, tension screw+titanium plate). The mechanical characteristics and changes of the mandible condyle under the same mechanical conditions were compared among the three different rigid internal fixation methods.
RESULTS:
The maximum equivalent stress and displacement of the non-free end of condyle under the rigid internal fixation method of unilateral tension screw were 71.03 MPa and 4.72 mm, respectively. The maximum equivalent stress and displacement of the free end of condyle were 78.45 MPa and 4.50 mm, respectively. The maximum stress of fracture suture was 3.27 MPa. The maximum equivalent stress and displacement of the non-free end of condyle under the rigid internal fixation method of bilateral tension screw were 70.52 MPa and 4.00 mm, respectively. The maximum equivalent stress and displacement of the free end of condyle were 72.49 MPa and 3.85 mm, respectively. The maximum stress of fracture suture was 2.33 MPa. The maximum equivalent stress and maximum displacement of the non-free end of condyle under the rigid internal fixation method of tension screw+titanium plate were 67.26 MPa and 2.66 mm, respectively. The maximum equivalent stress and maximum displacement of the free end of condyle were 69.66 MPa and 2.50 mm, respectively. The maximum stress of fracture suture was 2.18 MPa.
CONCLUSIONS
The tension screw+titanium plate rigid internal fixation method is the most conducive to biomechanical distribution for condylar head fractures.
Fracture Fixation, Internal/instrumentation*
;
Mandibular Condyle/surgery*
;
Biomechanical Phenomena
;
Bone Screws
;
Finite Element Analysis
;
Humans
;
Mandibular Fractures/surgery*
;
Bone Plates
;
Titanium
;
Stress, Mechanical
8.Conservative treatment of pathological fracture after multiple odontogenic keratocyst surgery: a case report and literature analysis.
Chen XU ; Hongguang CHANG ; Qiang SHAO ; Yonghai SONG
West China Journal of Stomatology 2025;43(1):144-150
Pathological fractures after jaw cyst surgery are rare clinically but are a serious complication. Once a pathological fracture occurs, treatment time and economic costs increase, and doctors face difficulty in handling it. This article reports a case of a patient with mandibular pathological fractures after multiple odontogenic keratocyst surgery of the jaw. Mandibular lesions were located in the bilateral mandibular angles and had macrocystic changes. We adopted a conservative treatment plan, and the treatment effect was good. We also discussed and analyzed relevant literature to provide a reference for clinicians.
Humans
;
Odontogenic Cysts/surgery*
;
Conservative Treatment
;
Postoperative Complications/therapy*
;
Mandibular Fractures/etiology*
;
Fractures, Spontaneous/etiology*
;
Male
;
Female
9.Clinical efficacy of in-situ crown reattachment technique combined with pulpotomy in the treatment of complica-ted crown-root fractures of young permanent anterior teeth.
Xuelong SU ; Qingyu GUO ; Meiyue REN ; Fei LIU
West China Journal of Stomatology 2025;43(4):499-504
OBJECTIVES:
This study aimed to evaluate the clinical application value of in-situ crown reattachment technique combined with pulpotomy in the treatment of complicated crown-root fractures in young permanent anterior teeth.
METHODS:
A prospective study was conducted on 50 children with complicated crown-root fractures in young permanent anterior teeth, who were treated at the Pediatric Dentistry Department, Hospital of Stomatology, Xi'an Jiaotong University from June 2023 to June 2024. All patients underwent in-situ crown reattachment technique combined with pulpotomy. Clinical examinations, radiographic evaluations, and subjective satisfaction surveys (using a Likert scale of 1-10) were conducted at 1, 6, and 12 months postoperatively. Data were analyzed using SPSS 23.0.
RESULTS:
The loss-to-follow-up rate was 12% (6/50), with 44 cases completing the 12 months of evaluation. The clinical success rate was 93.18% (41/44), and the radiographic success rate was 97.73% (43/44). The subjective satisfaction scores showed a significant improvement in masticatory function from 7.03±0.52 at 1 month to 8.07±0.92 at 12 months postoperatively (P<0.05), whereas the scores for aesthetics, comfort, and quality-of-life impact showed no statistically significant differences (P>0.05).
CONCLUSIONS
In-situ crown reattachment technique combined with pulpotomy effectively treats complicated crown-root fractures in young permanent anterior teeth, demonstrating a high short-term clinical success rate, significantly improved masticatory function, and minimally invasive preservation of pulp vitality and root development potential. This technique provides an optimized treatment option for dental trauma in children, although its long-term efficacy requires further validation.
Humans
;
Pulpotomy
;
Tooth Fractures/surgery*
;
Child
;
Prospective Studies
;
Male
;
Female
;
Tooth Root/injuries*
;
Tooth Crown/injuries*
;
Treatment Outcome
;
Incisor/injuries*
;
Child, Preschool
10.Resin short post retention for reattachment of a fractured crown in a young permanent tooth with complicated crown-root fracture and root fracture: a case report.
Yuanyuan WANG ; Huihui CHANG ; Birong ZHANG ; Zhiqing LIAO
West China Journal of Stomatology 2025;43(4):525-529
This report presents a case of a 9-year-old child with a complicated crown-root fracture of the maxillary central incisor, accompanied with a root fracture. The treatment strategy was minimally invasive, focusing on vital pulp preservation, root fracture recovery, and crown restoration. The fractured crown was reattached using resin short posts to enhance retention, resulting in aesthetic and functional restoration of the anterior teeth. A 2-year follow-up revealed favorable clinical and radiographic outcomes.
Humans
;
Child
;
Tooth Fractures/therapy*
;
Tooth Root/injuries*
;
Incisor/injuries*
;
Tooth Crown/injuries*
;
Post and Core Technique
;
Dental Restoration, Permanent/methods*
;
Maxilla


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