Objectives:To evaluate the impact of vertebroplasty on the blood loss during and after separation surgery for thoracolumbar metastasis.Methods:A total of 40 patients with single segment thoracolumbar metastases were divided into two groups of vertebroplasty group and control group.The vertebroplasty group(n=20)consisted of 12 males and 8 females,aged 45 to 68(average of 56.3±7.5)years old;The control group(n=20)consisted of 11 males and 9 females,aged from 45 to 70(average of 56.8±8.2)years old.All the pa-tients underwent posterior separation surgery,except vertebroplasty group received vertebroplasty after screw placement.There was no significant difference between the two groups of patients in age,gender ratio,prima-ry tumor,location of metastasis,Weinstein-Boriani-Biagini(WBB)classification,Tomita classification and score,main symptoms,and visual analogue scale(VAS)score(P＞0.05).The operatiove time,intraoperative blood loss,intraoperative blood transfusion,intraoperative fluid transfusion,postoperative drainage volume,and erythrocyte parameters were compared between the two groups.Results:The vertebroplasty group was significantly less than the control group in intraoperative blood loss(650.0±38.73mL vs 1139.0±57.17mL),blood transfusion(430.0±31.7mL vs 810.0±48.6mL),fluid transfusion(3080.0±769.6mL vs 3800.5±938.7mL),and postoperative drainage volume(501.5±355.5mL and 695.5±384.9mL)(P＜0.05).The operative time of the two groups were not significantly different(197.7±31.10min vs 207.7±43.9min,P=0.411).There was no significant difference between the two groups in preoperative hemoglobin,red blood cell count and hematocrit(HCT)(P＞0.05),which were de creased significantly after surgery.And the HCT of vertebroplasty group were higher than that in the control group[(36.40±4.89)％vs(30.46±5.49)％,P=0.001].Conclusions:Vertebroplasty in separation surgery of thora-columbar metastasis can significantly reduce the intraoperative blood loss,fluid transfusion,and blood transfu-sion,as well as the postoperative drainage volume,without time extension.

Objectives:To evaluate the impact of vertebroplasty on the blood loss during and after separation surgery for thoracolumbar metastasis.Methods:A total of 40 patients with single segment thoracolumbar metastases were divided into two groups of vertebroplasty group and control group.The vertebroplasty group(n=20)consisted of 12 males and 8 females,aged 45 to 68(average of 56.3±7.5)years old;The control group(n=20)consisted of 11 males and 9 females,aged from 45 to 70(average of 56.8±8.2)years old.All the pa-tients underwent posterior separation surgery,except vertebroplasty group received vertebroplasty after screw placement.There was no significant difference between the two groups of patients in age,gender ratio,prima-ry tumor,location of metastasis,Weinstein-Boriani-Biagini(WBB)classification,Tomita classification and score,main symptoms,and visual analogue scale(VAS)score(P＞0.05).The operatiove time,intraoperative blood loss,intraoperative blood transfusion,intraoperative fluid transfusion,postoperative drainage volume,and erythrocyte parameters were compared between the two groups.Results:The vertebroplasty group was significantly less than the control group in intraoperative blood loss(650.0±38.73mL vs 1139.0±57.17mL),blood transfusion(430.0±31.7mL vs 810.0±48.6mL),fluid transfusion(3080.0±769.6mL vs 3800.5±938.7mL),and postoperative drainage volume(501.5±355.5mL and 695.5±384.9mL)(P＜0.05).The operative time of the two groups were not significantly different(197.7±31.10min vs 207.7±43.9min,P=0.411).There was no significant difference between the two groups in preoperative hemoglobin,red blood cell count and hematocrit(HCT)(P＞0.05),which were de creased significantly after surgery.And the HCT of vertebroplasty group were higher than that in the control group[(36.40±4.89)％vs(30.46±5.49)％,P=0.001].Conclusions:Vertebroplasty in separation surgery of thora-columbar metastasis can significantly reduce the intraoperative blood loss,fluid transfusion,and blood transfu-sion,as well as the postoperative drainage volume,without time extension.