Objective To evaluate the influence of diagnostic curettage,hysteroscopic diagnostic curet-tage combined with MRI on the interpretation of pathology and cervical invation results of endometrial cancer.Methods The related medical records data of 1 135 patients with endometrial cancer treated in the Affiliated Banan Hospital of Chongqing Medical University and Anyue County People's Hospital from January 2012 to December 2023 were included.The preoperative imaging,histology and postoperative histology conducted the classification,grading and statistically comparison.Results The two methods by adopting diagnostic curettage or hysteroscopic diagnostic curettage sampling had certain proportions of underestimate of overestimate in the interpretation of preoperative pathological grading and histological typing.The preoperative tissues obtained by these two sampling methods in the coincidence rates of the pathological grading and histological typing had no statistically significant difference(P＞0.05).The sensitivity,specificity,positive predictive value(PPV),negative predictive value(NPV),positive likelihood ratio(+LR),negative likelihood ratio(-LR)and accu-racy of diagnostic curettage in judging cervical invasion were 56.96％,85.34％,34.62％,93.57％,3.89,0.46,and 81.94％respectively,and which in diagnostic hysteroscopic curettage combined with MRI were 73.08％,82.86％,36.54％,95.80％,4.26,0.32 and 81.69％,respectively.Conclusion The hysteroscopic diagnostic curettage could not increase the accuracy of histological typing and pathological grading of endometrial cancer.The hysteroscopic diagnostic curettage combined with MRI examination could more precisely evaluate the cer-vical invasion situation,guide the operation excision mode for cervix,peripheral tissues and lymph node and range selection.