Medical blood collection tubes need to be sealed and stored after testing.To solve the problem that the traditional plastic plug sealing device was not compatible with different sizes and specifications of blood collection tube sealing,a hospital blood collection tube sealing device was designed,including a track component,a blocking component,a clamping component,a film feeding component,a film sealing and folding component.Combined with the selection of sealing parameters and fatigue test,it was shown that the blood collection tube sealing device could achieve high compatibility,high efficiency,simple structure and high reliability for sealing blood collection tubes and meet the needs of clinical testing.