1.Analysis of Surgical Treatment Outcomes in 709 Cases of Infective Endocarditis
Chaoji ZHANG ; Zining WU ; Xingrong LIU ; Guotao MA ; Shangdong XU ; Jianzhou LIU ; Sheng YANG ; Yanxue ZHAO ; Xinpei LIU ; Xiaocui WANG ; Xiaojun MA ; Ligang FANG ; Chunhua YU ; Huaiwu HE ; Qi MIAO ; Jun ZHENG
Medical Journal of Peking Union Medical College Hospital 2025;17(1):197-203
To review the clinical characteristics, short-term outcomes, and risk factors of patients with infective endocarditis(IE) who underwent surgical treatment at a single center, and to summarize treatment experience. Consecutive patients diagnosed with IE who underwent cardiac surgery at the Department of Cardiac Surgery, Peking Union Medical College Hospital between May 2012 and June 2024 were enrolled. Statistical analyses were performed on their baseline characteristics, comorbidities, IE predisposing factors, surgical indications, pathogen distribution, surgical strategies, short-term outcomes, and associated risk factors. A total of 709 IE patients meeting the inclusion and exclusion criteria were included. IE involved left-sided valves in 85.3% of cases. The median age was 48(35, 58) years, and 68.0% were male. Prosthetic valve endocarditis accounted for 8.7%. Patients with left-sided IE had a higher prevalence of comorbidities. Streptococcus was the causative pathogen in 43.2% of patients, while right-sided IE was more frequently associated with Significant differences in pathogen distribution were observed between patients with left-sided and right-sided IE. Heart failure was identified as an independent risk factor for both perioperative mortality and adverse outcomes in surgically treated patients. Through strict timing of surgical intervention and optimized perioperative management, surgical treatment may effectively reduce mortality and improve prognosis in patients with IE.
2.Health education needs of patients undergoing fecal microbiota transplantation at different stages: a qualitative study
Sining ZENG ; Ling XU ; Zining GUO ; Shufan CHEN ; Keyu LING ; Haihan LI ; Xiaoping ZHU
Chinese Journal of Modern Nursing 2025;31(7):868-874
Objective:To explore the health education needs of patients undergoing fecal microbiota transplantation (FMT) at different stages of treatment.Methods:A qualitative research method was employed and an interview guide based on timing theory was developed. Semi-structured interviews were conducted with patients treated for colorectal conditions with FMT at Tenth People's Hospital of Tongji University from August to October 2022. Data from the interviews were analyzed using thematic analysis.Results:A total of 19 patients aged 20 to 65 were interviewed, including seven males and 12 females. A total of five main themes and 15 subthemes were identified: health education demands during the diagnosis phase (basic information about FMT; knowledge about donor screening), health education demands during the preparation phase (alleviating discomfort caused by nasoenteric tubes; interpretation of examination reports), health education demands during the execution phase (dietary guidance during FMT; exercise guidance during FMT; medication and supplementary training guidance; management of adverse reactions), health education demands during the adaptation phase (consolidating treatment effects; knowledge related to FMT capsules; post-discharge follow-up content and methods; post-discharge precautions), long-term health education demands (diverse health education tools; individualized health education approaches; alleviating psychological anxiety) .Conclusions:Patients undergoing FMT have numerous concerns, and diverse health education needs throughout the treatment process. Healthcare professionals should adopt various health education strategies to address these needs.
3.Health education needs of patients undergoing fecal microbiota transplantation at different stages: a qualitative study
Sining ZENG ; Ling XU ; Zining GUO ; Shufan CHEN ; Keyu LING ; Haihan LI ; Xiaoping ZHU
Chinese Journal of Modern Nursing 2025;31(7):868-874
Objective:To explore the health education needs of patients undergoing fecal microbiota transplantation (FMT) at different stages of treatment.Methods:A qualitative research method was employed and an interview guide based on timing theory was developed. Semi-structured interviews were conducted with patients treated for colorectal conditions with FMT at Tenth People's Hospital of Tongji University from August to October 2022. Data from the interviews were analyzed using thematic analysis.Results:A total of 19 patients aged 20 to 65 were interviewed, including seven males and 12 females. A total of five main themes and 15 subthemes were identified: health education demands during the diagnosis phase (basic information about FMT; knowledge about donor screening), health education demands during the preparation phase (alleviating discomfort caused by nasoenteric tubes; interpretation of examination reports), health education demands during the execution phase (dietary guidance during FMT; exercise guidance during FMT; medication and supplementary training guidance; management of adverse reactions), health education demands during the adaptation phase (consolidating treatment effects; knowledge related to FMT capsules; post-discharge follow-up content and methods; post-discharge precautions), long-term health education demands (diverse health education tools; individualized health education approaches; alleviating psychological anxiety) .Conclusions:Patients undergoing FMT have numerous concerns, and diverse health education needs throughout the treatment process. Healthcare professionals should adopt various health education strategies to address these needs.
4.Hotspots and trends in acupuncture-assisted tumor chemotherapy: a bibliometric analysis based on CiteSpace and VOSviewer.
Wenhao LIU ; Wenting LIU ; Letian HUANG ; Zining GUO ; Ying LIANG ; Haibo ZHANG ; Nenggui XU ; Yihan HE
Chinese Acupuncture & Moxibustion 2024;44(12):1453-1462
OBJECTIVE:
To review the current research status and hotspots of acupuncture-assisted tumor chemotherapy and provide references for clinical and basic research in this field.
METHODS:
The relevant literature on acupuncture-assisted tumor chemotherapy from the inception of the China National Knowledge Infrastructure (CNKI) and Web of Science (WoS) databases to December 10, 2023, was retrieved. CiteSpace6.2.R4 and VOSviewer1.6.20 software was used to analyze publication volume, authors, institutions, source journals, and keywords, etc. and to create visualized mapping.
RESULTS:
A total of 2 116 articles were included (1 829 from CNKI and 287 from WoS), showing an overall upward trend in publication volume. The scope of acupuncture-assisted tumor chemotherapy has expanded, with a growing variety of research types. In CNKI, the most prolific authors and institutions were from Henan University of CM, forming core research teams. In WoS, the most prolific author was Bao T, and the leading institution was Kyung Hee University in South Korea, although author and institution distribution was more scattered, with close inter-regional collaboration. There were 602 keyword nodes in CNKI and 383 in WoS, with high-frequency keywords in both databases mainly focusing on treatment protocols, cancer types, and chemotherapy-related adverse reactions. CNKI publications highlighted frequent use of acupoints, with more diverse acupoint protocol options, while WoS focused more on different research methods. Recent CNKI studies have focused on improving immune function and quality of life, while "systematic review" emerged as a key term in WoS.
CONCLUSION
Research on acupuncture-assisted tumor chemotherapy should further strengthen collaboration and communication, focus on improving clinical evidence, and promote wider application of acupuncture in integrative oncology research.
Humans
;
Acupuncture Therapy
;
Bibliometrics
;
Neoplasms/drug therapy*
;
Antineoplastic Agents
;
China
5.Dilemmas in decision-making:a qualitative study of family surrogate decision-makers of severe stroke patients
Zining GUO ; Keyu LING ; Shufan CHEN ; Haihan LI ; Ting YAO ; Sining ZENG ; Ling XU ; Xiaoping ZHU
Chinese Journal of Nursing 2024;59(14):1746-1751
Objective To explore the dilemmas faced by surrogate decision-makers of severe stroke patients in treatment decision-making,and to provide a basis for developing decision support strategies.Methods From April to December 2023,through phenomenological qualitative research with 16 surrogate decision-makers with severe stroke patients from ICU of the department of neurology in a tertiary hospital in Jing'an District,Shanghai.semi-structured in-depth interviews were used to examine the perceptions of decision-making on surrogate.Data were analyzed via Braun's style of thematic analysis.Results 4 themes and 10 sub-themes were identified.Theme 1:negative emotional dilemmas(urgent decision-making leads to anxiety,fear,and unknown stroke trajectory increases the sense of uncertainty).Theme 2:supportive environment dilemmas(lack of information support delays decision-making;lack of family support increases decision-making stress;insufficient economic support increases the burden of decision-making).Theme 3:the dilemma of weighing the pros and cons(difficult trade-offs between risk and reward,tough decisions between reality and ethics,conflicting choices of life and dignity).Theme 4:preference management dilemmas(practical difficulties in adhering to patient preferences,impediments to decision-making due to unknown patient preferences).Conclusion Surrogate decision-makers of severe stroke patients face multiple decision-making dilemmas.Healthcare professionals should provide emotional support in multiple ways and comprehensive support to reduce the decision-making dilemmas experienced by surrogate decision-makers,as well as implement death education for surrogate decision-makers and promote advance care planning to reduce their decision-making stress.
6.Journey map of chronic constipation patients undergoing fecal microbiota transplantation
Haihan LI ; Shufan CHEN ; Keyu LING ; Shailan ZHOU ; Zining GUO ; Ling XU ; Sining ZENG ; Xiaoping ZHU
Chinese Journal of Modern Nursing 2024;30(34):4662-4669
Objective:To explore the journey map of patients with chronic constipation during fecal microbiota transplantation.Methods:This study adopted phenomenological methods. From October to December 2023, purposive sampling was used to select chronic constipation follow-up patients who underwent fecal microbiota transplantation at the Intestinal Microecology Center of Shanghai Tenth People's Hospital as respondents for semi-structured interviews. Colaizzi 7-step analysis method and NVivo 11.0 software were used for data analysis.Results:A total of 15 interviewees were interviewed. During fecal microbiota transplantation, the journey map of constipation patients included stages, mood changes, touchpoints, themes, emotional experiences and opportunities. The patient's experience and needs were summarized into three themes and ten sub-themes, including pre-transplant adaptation disorders to new environments (unfamiliarity and confusion-admission coordination disorders, anxiety and expectations-diverse complex emotions, puzzle and helplessness-asymmetric doctor and patient information), effectiveness-related psychological and social experiences in transplantation (attention and expectations-longing for positive efficacy, perception of benefits and risk avoidance, shame and inferiority-treatment stigmatization experience, questioning and despair-unrealized expectations, treatment resistance-sensitive economic burden), post-transplant transition dilemmas (inaccessible medical services-lack of continuous treatment and nursing, disease recurrence troubles) .Conclusions:This study visualizes the experiences and needs of constipation patients during microbiota transplantation through a patient journey map and identifies multidimensional issues and needs of patients. Clinical medical and nursing staff should pay attention to the needs of patients at different stages of the treatment process when formulating intervention programs to improve the quality of fecal microbiota transplantation nursing.
7.Investigation of radiation protection status of non-medical radiation institutions in Nantong, China, 2023
Yuan LI ; Ende ZHONG ; Yaqiang CAO ; Cheng SUN ; Zining XU
Chinese Journal of Radiological Health 2024;33(6):686-691
Objective To investigate and analyze the current situation of radiation protection in non-medical radiation institutions in Nantong, China, 2023, and to provide data support for local health supervision departments to formulate more scientific and reasonable occupational health management measures. Methods Based on the radiation health information management platform of Jiangsu Province, the data reported in 2023 were collected through online questionnaire survey. Seven institutions were selected for on-site test. The survey and test data were analyzed. Results There were
8.Evaluation of tubal patency by hysterosalpingo-contrast sonography: moving forward in controversies and dilemmas
Zining XU ; Yaoting WANG ; Juan SUN ; Shuangxi CHEN ; Yan ZOU ; Ailin CUI ; Jing SHU
Chinese Journal of Reproduction and Contraception 2024;44(6):656-660
In recent years, the incidence rate of tubal infertility has been rising. In China, most patients with tubal infertility prioritize conservative management or tubal reconstruction surgery in order to preserve fallopian tubes as far as possible. In order to meet the reproductive needs of tubal infertile patients, clinicians in the reproductive field need to evaluate various infertility risk factors comprehensively, weigh the pros and cons, and explore individualized reproductive programs which are more in line with the interests of patients. Correspondingly, higher requirements for the imaging evaluation efficiency of the fallopian tubes have been put forward. Hysterosalpingo-contrast sonography (HyCoSy), as a first-line imaging technique for evaluating tubal patency, still faces many controversies and dilemmas despite its value being widely recognized in clinical practice. This paper aims to provide viewpoints for the advancement of HyCoSy by reviewing literature and summarizing experiences.
9.Evaluation of tubal patency by hysterosalpingo-contrast sonography: moving forward in controversies and dilemmas
Zining XU ; Yaoting WANG ; Juan SUN ; Shuangxi CHEN ; Yan ZOU ; Ailin CUI ; Jing SHU
Chinese Journal of Reproduction and Contraception 2024;44(6):656-660
In recent years, the incidence rate of tubal infertility has been rising. In China, most patients with tubal infertility prioritize conservative management or tubal reconstruction surgery in order to preserve fallopian tubes as far as possible. In order to meet the reproductive needs of tubal infertile patients, clinicians in the reproductive field need to evaluate various infertility risk factors comprehensively, weigh the pros and cons, and explore individualized reproductive programs which are more in line with the interests of patients. Correspondingly, higher requirements for the imaging evaluation efficiency of the fallopian tubes have been put forward. Hysterosalpingo-contrast sonography (HyCoSy), as a first-line imaging technique for evaluating tubal patency, still faces many controversies and dilemmas despite its value being widely recognized in clinical practice. This paper aims to provide viewpoints for the advancement of HyCoSy by reviewing literature and summarizing experiences.
10.Qualitative study on frailty perception and coping experiences of elderly patients with hip fractures
Yuting HUANG ; Fei LIU ; Ling XU ; Sining ZENG ; Keyu LING ; Zining GUO ; Xiaoping ZHU
Chinese Journal of Modern Nursing 2024;30(35):4790-4796
Objective:To understand the frailty perception and coping experiences of elderly patients with hip fractures from the patients' perspective, providing insights for healthcare professionals on managing frailty.Methods:A purposive sampling method was used to select 12 elderly patients with hip fractures and frailty who were hospitalized at Tenth People's Hospital of Tongji University from September to October 2023. A phenomenological approach was adopted for this qualitative study, conducting semi-structured interviews to explore the patients' frailty perceptions and coping experiences. NVivo 11.0 software and Colaizzi's seven-step analysis method were used to organize and analyze the interview data.Results:The frailty perceptions of elderly hip fracture patients were categorized into four themes: multidimensional physiological challenges (e.g., aging of the body, nutritional imbalances, pain and sleep disturbances) ; limitations in daily life (e.g., mobility impairments, avoidance of social activities) ; heavy psychological burdens (e.g., uncertainty about the illness, low self-efficacy, feelings of guilt towards the family) ; insufficient social support (e.g., lack of age-friendly environments and limited medical policy coverage). The patients' coping strategies were grouped into two themes: active coping (e.g., self-encouragement, peer support, actively seeking relevant knowledge and guidance) ; passive coping (e.g., neglecting the situation) .Conclusions:Frailty brings multiple negative impacts on the physical, psychological, daily life and social aspects of elderly hip fracture patients; while most patients adopt a positive attitude towards frailty, some exhibit signs of emotional exhaustion and passivity. Medical staff should pay attention to the frailty perceptions of elderly hip fracture patients, identify related symptoms early, provide comprehensive support to alleviate the physical and psychological burden, and encourage patients to face frailty challenges optimistically, adopting proactive measures to slow its progression.

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