Objective:To develop and validate a prediction model for medication adherence among patients receiving allergen sublingual immunotherapy (SLIT).Methods:A prospective cross-sectional study was conducted, and a total of 288 patients who received SLIT treatment at an allergy center in the First Affiliated Hospital with Nanjing Medical University (Jiangsu Province Hospital) from December 2023 to July 2024 were assigned to the modeling group. Additionally, 122 patients from August to October 2024 were assigned to the validation group. Data of patients′ general information, medication beliefs, anxiety levels, social support, disease perception, and medication adherence were collected. Single-factor analysis and LASSO regression were utilized to identify potential predictors, and a prediction model for medication adherence was constructed using multifactorial logistic regression. A nomogram was then developed based on the model. The model′s discriminatory ability was evaluated using receiver operating characteristic curve (ROC), the area under curve (AUC), sensitivity, and specificity. The model was then validated in the validation cohort.Results:Single-factor analysis and LASSO regression identified a total of nine predictive factors. Logistic regression revealed that medical belief tendency [ OR (95% CI) =2.420 (1.116-5.248), P=0.025], the somatic control dimension in self-rating anxiety scales [ OR (95% CI)=1.404 (1.241-1.589), P<0.001], the subjective support dimension in social support assessment [ OR (95% CI)=0.784 (0.725-0.847), P<0.001], and the cognitive dimension in illness perception [ OR (95% CI)=0.725 (0.647-0.813), P<0.001] were independent predictors of medication adherence in patients undergoing SLIT. The AUC value of the model was 0.899 (95% CI=0.863-0.934) in the modeling group and 0.882 (95% CI=0.820-0.944) in the validation group, indicating good discriminatory ability. The optimal cutoff value of the model was 0.493, with a sensitivity of 81.1% and specificity of 85.7% in the modeling group, and a sensitivity of 87.3% and specificity of 82.5% in the validation group. Conclusion:The medication adherence prediction model developed in this study for patients undergoing SLIT exhibits good predictive performance and provides valuable guidance for early intervention by clinical healthcare professionals.

Objective:To develop and validate a prediction model for medication adherence among patients receiving allergen sublingual immunotherapy (SLIT).Methods:A prospective cross-sectional study was conducted, and a total of 288 patients who received SLIT treatment at an allergy center in the First Affiliated Hospital with Nanjing Medical University (Jiangsu Province Hospital) from December 2023 to July 2024 were assigned to the modeling group. Additionally, 122 patients from August to October 2024 were assigned to the validation group. Data of patients′ general information, medication beliefs, anxiety levels, social support, disease perception, and medication adherence were collected. Single-factor analysis and LASSO regression were utilized to identify potential predictors, and a prediction model for medication adherence was constructed using multifactorial logistic regression. A nomogram was then developed based on the model. The model′s discriminatory ability was evaluated using receiver operating characteristic curve (ROC), the area under curve (AUC), sensitivity, and specificity. The model was then validated in the validation cohort.Results:Single-factor analysis and LASSO regression identified a total of nine predictive factors. Logistic regression revealed that medical belief tendency [ OR (95% CI) =2.420 (1.116-5.248), P=0.025], the somatic control dimension in self-rating anxiety scales [ OR (95% CI)=1.404 (1.241-1.589), P<0.001], the subjective support dimension in social support assessment [ OR (95% CI)=0.784 (0.725-0.847), P<0.001], and the cognitive dimension in illness perception [ OR (95% CI)=0.725 (0.647-0.813), P<0.001] were independent predictors of medication adherence in patients undergoing SLIT. The AUC value of the model was 0.899 (95% CI=0.863-0.934) in the modeling group and 0.882 (95% CI=0.820-0.944) in the validation group, indicating good discriminatory ability. The optimal cutoff value of the model was 0.493, with a sensitivity of 81.1% and specificity of 85.7% in the modeling group, and a sensitivity of 87.3% and specificity of 82.5% in the validation group. Conclusion:The medication adherence prediction model developed in this study for patients undergoing SLIT exhibits good predictive performance and provides valuable guidance for early intervention by clinical healthcare professionals.

Patients' subjective feelings, that is, patient-reported outcomes, has attracted increasing attention in patients with inflammatory bowel disease (IBD) , which plays an important role in monitoring the progress of patients' disease and guiding clinical decision-making. This article reviews the current status of assessment tools and clinical applications of patient-reported outcomes in IBD patients. This article aims to help medical and nursing staff choose assessment tools suitable for IBD patients in China, standardize the development and localization process of assessment tools, promote the application and development of patient-reported outcomes of IBD patients in China, and optimize disease management of IBD patients.

Inflammatory bowel disease (IBD) is a chronic non-specific intestinal inflammatory disease of unknown etiology, which is characterized by recurrent episodes and prolonged refractory recovery. Financial toxicity refers to the objective economic burden and subjective economic distress caused by medical expenses caused by the disease to patients. IBD patients show a certain level of financial toxicity due to frequent visits to doctors for a long time. This article reviews the concept of financial toxicity, evaluation tools and the current status of financial toxicity in IBD patients, analyzes the influencing factors of financial toxicity in IBD patients from the aspects of general demography factors, disease and treatment and psychosocial aspects, summarizes and puts forward the countermeasures of toxicity of IBD patients to reduce the economic and the direction of the future study, so as to provide reference for related research.

Objective:Scope review of exercise-related research in patients with inflammatory bowel disease (IBD), while pointing out the limitations of existing research, and providing references for future studies in this area.Methods:We searched PubMed, EMBASE, Web of science, Cochrane databases, China Biology Medicine, Chinese National Knowledge Infrastructure, Wan Fang Data, and Chinese Science Journal Database for studies related to exercise intervention in patients with IBD from January 1974 to July 2020. We extracted data from the included studies. Then we summarized and presented the results.Results:16 articles were finally included, of which 14 were randomized controlled trials and 2 were quasi-experimental studies. Results show that exercise methods can be divided into four categories: aerobic exercise, resistance exercise, flexibility exercise and mixed exercise. The intensity of exercise was mostly low to moderate. The frequency of exercise was mostly 3 times/week, lasting for 30-60 minutes per session. The results showed that exercise had positive effects on physical fitness, bone density, anxiety and depression, quality of life among patients with IBD. However, the effect of exercise on disease activity are diverse.Conclusion:exercise is beneficial to the mental and physical health among this group, but the existing studies have small sample sizes, short exercise intervention period, neglect of individualization in exercise prescription design, low exercise compliance, non-uniformity of exercise effect evaluation indicators.

This paper analyzes and compares the development of Traditional Chinese Medicine (TCM) in Germany, France, the UK and Netherlands, considering the economic and social situation of countries. The SWOT strategic analysis is carried out on the basis of the proposittion of China-Europe cooperation in TCM, which encourage to carry out joint tackling of TCM for common diseases, jointly promoting the legislation with the guidance of the government and the participation of the public, speeding up the registration and listing of Chinese patent medicine with the focus on the Netherlands and the UK, and optimizing the perspective and strength of TCM publicity with the help of new media. In this way, TCM should be promoted in Europe.

Self-disclosure is a simple and effective intervention to improve the health outcomes of patients. Foreign scholars have paid attention to it and applied it in the self-management of patients with chronic diseases widely. However, there are few domestic related studies in China. This article reviewed the definition, significance, assessment tools, and summarized the influencing factors and intervention studies of self-disclosure in patients with chronic diseases. It would provide references for research of self-disclosure, further improving the self-management and mental health of patients with chronic diseases.

Objective:To explore the research hotspots and development trends of male nurses in China from 2009 to 2019 by bibliometric analysis, and provide references for related research.Methods:Relevant literature on male nurses in my country from 2009 to 2019 were retrieved through Wanfang Data, China National Knowledge Infrastructure (CNKI) , VIP, China Biology Medicine and other databases. The content of the included literature was analyzed, and word frequency analysis as well as two-way cluster analysis on keywords were performed by bicomb 2.0 software and gCLUTO 1.0 software.Results:A total of 931 journal articles were included, and 25 high-frequency keywords were obtained. Three research hotspots were obtained through cluster analysis, namely, male nurses' work advantages and management, male nurses' mental health, and male nursing students' nursing education.Conclusions:Male nurses are receiving increasing attention, and core journal forums have begun to take shape, but the overall research quality is not good. In the future, it is necessary to strengthen the scientificity and rigor of scientific research design and research implementation, so as to enhance the guiding value of literature for clinical practice.

Objective:To understand the research status of positive psychology in the world, analyze its development trend and provide reference for the research of positive psychology in China.Methods:The research literatures on positive psychology from 2000 to 2019 were retrieved in Web of Science Core Collection database.Its built-in analytical function was used for bibliographic analysis of annual distribution, country distribution, fund supporting institutions, journal distribution, and research direction. CiteSpace 5.1.R6 software was used to draw high-frequency keywords maps to analyze research hotspots, and HistCite Pro 2.1 software was used to draw citation chronicle chart to analyze highly cited literatures.Results:A total of 4 536 literatures related to positive psychology were included, and the number of literatures showed an increasing trend year by year. The United States had the most publications, with 1 793 papers. And the number of published papers in China was 241, ranking 6th. Funding agencies and journals were scattered, but mostly from the United States. Research focused on psychology (52.491%, 2 381/4 536) , and nursing ranked 10th (1.984%, 90/4 536) . Adolescents, subjective positive experiences and personal positive traits were research hotspots.The 10 most frequently cited studies focused on positive emotions and experiences, positive psychological interventions and validation of their effectiveness.Conclusions:Positive psychology research is in a stage of continuous development and growth, and the core journal forum has not yet formed.The United States occupies a leading position in this field of research, and there is still a great room for improvement in the quantity and quality of research in this field in China.In the future, researchers can conduct in-depth studies on children, the elderly and the positive social environment, and at the same time, combine with local characteristics to explore the theoretical system and intervention mode of positive psychology suitable for China.