Allergic comorbidity is a common allergic-related disease in the department of pediatrics,which is called atopic triad in modern medicine.Professor Xu Youjia believes that the children with allergic comorbidity have a more distinctive constitution of insufficiency of immature yang.Children with allergic comorbidity initially have the spleen-qi deficiency pathogenesis,and then the kidney yang will be further involved if the children fail in timely regulation and supplementation,which will result in kidney yang deficiency.In the view of spleen-kidney deficiency-cold pathogenesis of children with allergic comorbidity,Professor Xu Youjia suggested that,during the treatment,attention should be paid to the protection of the spleen(earth)of the middle energizer,thus to ensure the postnatal fire warm congenital kidney yang,and then the efficacy of raising qi and reinforcing yang can be achieved.The core medicines used for the treatment of deficiency-cold snineling nose include seven herbs,and they were Glycyrrhizae Radix et Rhizoma,Atractylodis Macrocephalae Rhizoma,Angelicae Dahuricae Radix,Saposhnikoviae Radix,Xanthii Fructus,Magnoliae Flos,and Schisandrae Chinensis Fructus.For children with severe deficiency-cold,the treatment needs to start from supplementing kidney-qi and protecting the root of yang,and the medicinals such as Psoraleae Fructus,Cimicifugae Rhizoma,Eucommiae Cortex,and Cinnamomi Cortex can be used.Professor Xu stressed the importance of adjusting the children's dietary structure and habits for protecting the spleen and stomach.The application of therapy of mediating the middle earth,raising qi and strengthening yang should accord with the growth and development of children,and the therapy is suitable for guiding the clinical treatment of diseases related to deficiency-cold syndrome.The selection of prescriptions should be based on the identification of the pathogenesis of deficiency-cold and its severity.

The literature and books of Lingnan classical medicine books of pediatrics from China Classic was retrieved. This paper analyzed and summarized four body constitutional features for Lingnan children, including vulnerable Zang viscera, spleen-stomach deficiency, tendency to dryness-heat and dampness prevalent diseases. This paper provided the evidence for Lingnan children's constitution identification and prevention and treatment of diseases.

The TCM theory over body constitution has been greatly developed in the past several decades.However,the body constitution for children still lacks a standard classification.Available studies often ignored the impacts of the factors,such as region,climate and diet,on the body constitution of children.Given this situation,the present review focused on the research progress on the discipline of TCM body constitution and its classification and differentiation in Chinese children,and put forward the development on this issue based on current state policy and our own research experience.It was suggested that scholars develop a well-recognized classification method for the TCM body constitution for children in a particular region before investigating interventions according to TCM body constitution.

Objective To evaluate the efficacy and safety of Sheng-qi-zhuang-yang formula combined with specific immunotherapy (SIT) with standardized house dust mite vaccine on allergic asthmatic children. Methods Participants were 100 children with mild to moderate allergic asthma , who were receiving SIT at Guangdong Provincial Hospital of Chinese Medicine from Jan 2011 to Dec 2013 , who were divided into treatment group and control group. Patients in the treatment group received Sheng-qi-zhuang-yang Decoction combined with SIT while patients in the control group received SIT alone. Asthma symptom scores, respiratory function and related adverse events were compared before and after treatment, between groups. Results The desensitization treatment functions was ahead of time than expected in both groups. There is no significant difference between groups in terms of respiratory function and adverse effects. Conclusion Sheng-qi-zhuang-yang decoction combined with SIT for allergic asthmatic children seems to advance clinical effect without increasing adverse events. Further large scale clinical trial is required to confirm this.