1.Study on correlation between SWE hardness measurement of calf muscle and MNSI score in patients with diabetes mellitus
Zhongyuan HUO ; Hongyan ZHAO ; Ying ZHANG ; Dandan ZHANG ; Wei TIAN
China Modern Doctor 2024;62(19):50-53
Objective To analyze the correlation between shear wave elastography(SWE)hardness measurements of calf muscle in diabetic mellitus patients and Michigan neuropathy screening instrument(MNSI)score.Methods A total of 102 patients with diabetes mellitus who were hospitalized in Lianyungang Hospital of Traditional Chinese Medicine from August 2020 to February 2022 were selected as study object.According to MNSI score,diabetes mellitus patients were divided into group A(0 points ≤MNSI score ≤ 1 point,20 cases),group B(1 point<MNSI score ≤ 2 points,32 cases),group C(2 points<MNSI score≤ 3 points,26 cases)and group D(3 points<MNSI score ≤4 points,24 cases).Thirty normal volunteers were selected as control group.The values of Young modulus of calf gastrocnemius,tibialis anterior and peroneus were measured by SWE and compared under different tension states.Spearman correlation test was used to examine the relationship between MNSI score and Young modulus of calf muscle.Results With the increase of MNSI score,the Young modulus of each calf muscle shear wave decreased in all groups,and the differences between groups were statistically significant(P<0.05).Young modulus of maximum plantar flexion of gastrocnemius,maximum dorsiflexion of gastrocnemius,maximum plantar flexion of tibialis anterior and peroneus foot varus in diabetic patients were negatively correlated with MNSI score(P<0.05),and the correlation coefficients were-0.74,-0.73,-0.72 and-0.75,respectively.Conclusion With the aggravation of peripheral neuropathy in diabetes mellitus patients and the decrease of shear wave hardness of calf muscle,SWE can comprehensively evaluate diabetic peripheral neuropathy with MNSI score.
2.Ultrasonic measurement and correlation of sural nerve and Achilles tendon in patients with diabetic peripheral neuropathy
Zhongyuan HUO ; Xinxin WANG ; Hongyan ZHAO
Journal of Apoplexy and Nervous Diseases 2020;37(4):341-344
Objective To investigate the changes and correlation of ultrasound measurements of sural nerve and Achilles tendon in patients with type 2 diabetic peripheral neuropathy.Methods High-frequency ultrasound was used to analyze the internal structure and surrounding tissues of the sural nerve and Achilles tendon in 42 patients with type 2 diabetes mellitus with DPN,42 patients with T2DM without DPN and 42 non-diabetic healthy adults.The cross-sectional area of the sural nerve and the thickness of the Achilles tendon near the end.The cross-sectional area of the sural nerve and the thickness of the achilles tendon near the end were compared between the groups,and Pearson correlation analysis and scatter statistics was performed.Results The abnormal sonogram of the DPN group was significantly higher than that of the NDPN group.The number of abnormal sonograms detected in the DPN group was 36 cases,accounting for 83.33%.The abnormal sonograms detected in the non-DPN group were 14 cases,accounting for 33.33 %.The cross-sectional area of the sural nerve and the thickness of the Achilles tendon in the DPN group were larger than those in the NDPN group and the non-diabetic group,and the difference was statistically significant (P<0.05).The cross-sectional area of the sural nerve was positively correlated with the thickness of the Achilles tendon in patients with DPN (r=0.747,P<0.05).Conclusion The incidence of sural nerve and Achilles tendon lesions is high in patients with diabetic peripheral neuropathy.High-frequency ultrasound can help to detect the sural nerve and Achilles tendon lesions in patients with DPN.They are of great value in the collaborative assessment of DPN lesions.


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