Objective To study the five-year survival status and influencing factors of elderly patients with lung cancer complicated with chronic obstructive pulmonary disease (COPD). Methods A cohort study was conducted to follow up 450 patients with lung cancer and chronic obstructive pulmonary disease who were hospitalized in our hospital from January 2018 to December 2023. The endpoint of the follow-up was the end of a five-year period or death. The Life Tables method was used to calculate survival rates and plot survival curves. The Cox proportional hazards model was used to analyze the influencing factors of five-year survival. Results The results indicated that the overall five-year survival rate of patients was 4.89%, and it decreased year by year. Cox regression analysis showed that age, gender, family functioning, and psychological status significantly influenced patient survival rate (all P<0.05). Stratified analysis found that the smoking status, family functioning, and psychological status of male patients all had an impact on survival rate (all P<0.05), while the psychological status of female patients had a more significant impact on survival (P=0.008). Conclusion This study provides a scientific basis for comprehensive intervention of elderly lung cancer patients with COPD. It is recommended that clinical attention should be paid to psychological and family factors to improve patient prognosis.

Objective:To compare the cost-effectiveness of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) versus percutaneous endoscopic discectomy (PTED) for the treatment of single-segment lumbar disc herniation (LDH). Methods:This study is a retrospective analysis that included patients diagnosed and treated with either MIS-TLIF or PTED for single-segment LDH at Hefei First People's Hospital from January to December 2022. The study comprised 35 patients in the MIS-TLIF group and 35 patients in the PTED group. Total medical costs, surgery duration, blood loss, time to catheter removal, Visual Analog Scale scores before surgery, and at 3 and 12 months post-surgery, along with the Oswestry Disability Index, were recorded for each group. The cost-effectiveness ratio was compared between the two groups.Results:A total of 70 patients were included, including 35 patients in the MIS-TLIF group and 35 patients in the PTED group. There was no significant difference in general data between the two groups (all P >0.05). The differences in Visual Analog Scale and Oswestry Disability Index scores between the two groups, as well as within each group before surgery, and at 3 and 12 months post-surgery, were not statistically significant (all P > 0.05). The surgery duration for the PTED group [(112.94 ± 53.17) minutes] was significantly shorter than that of the MIS-TLIF group [(210.14 ± 25.68) minutes, Z = 2.21, P < 0.05]. However, the success rate for the PTED group [94.29% (33/35)] was not significantly different from that of the MIS-TLIF group [91.43% (32/35), Z = 0.46, P > 0.05]. The cost-effectiveness ratio for the PTED group was 239.56, while the cost-effectiveness ratio for the MIS-TLIF group was 377.69. Conclusions:PTED offers greater economic advantages in the treatment of single-segment LDH, particularly in terms of reduced blood loss and shorter surgery duration compared with MIS-TLIF. The choice of surgical approach should be made according to clinical requirements.

Objective:To compare the cost-effectiveness of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) versus percutaneous endoscopic discectomy (PTED) for the treatment of single-segment lumbar disc herniation (LDH). Methods:This study is a retrospective analysis that included patients diagnosed and treated with either MIS-TLIF or PTED for single-segment LDH at Hefei First People's Hospital from January to December 2022. The study comprised 35 patients in the MIS-TLIF group and 35 patients in the PTED group. Total medical costs, surgery duration, blood loss, time to catheter removal, Visual Analog Scale scores before surgery, and at 3 and 12 months post-surgery, along with the Oswestry Disability Index, were recorded for each group. The cost-effectiveness ratio was compared between the two groups.Results:A total of 70 patients were included, including 35 patients in the MIS-TLIF group and 35 patients in the PTED group. There was no significant difference in general data between the two groups (all P >0.05). The differences in Visual Analog Scale and Oswestry Disability Index scores between the two groups, as well as within each group before surgery, and at 3 and 12 months post-surgery, were not statistically significant (all P > 0.05). The surgery duration for the PTED group [(112.94 ± 53.17) minutes] was significantly shorter than that of the MIS-TLIF group [(210.14 ± 25.68) minutes, Z = 2.21, P < 0.05]. However, the success rate for the PTED group [94.29% (33/35)] was not significantly different from that of the MIS-TLIF group [91.43% (32/35), Z = 0.46, P > 0.05]. The cost-effectiveness ratio for the PTED group was 239.56, while the cost-effectiveness ratio for the MIS-TLIF group was 377.69. Conclusions:PTED offers greater economic advantages in the treatment of single-segment LDH, particularly in terms of reduced blood loss and shorter surgery duration compared with MIS-TLIF. The choice of surgical approach should be made according to clinical requirements.