1.Multimodal Data-Driven Prediction of Gynecological Surgery Duration
Yong HUANG ; Zhilin YONG ; Banghua WU ; Xueying ZHOU ; Xiaoling LANG ; Yuming LI ; Miye WANG ; Qingke SHI ; Li RAO
Journal of Sichuan University (Medical Sciences) 2025;56(5):1392-1398
Objective Focusing on gynecological surgery,we constructed a prediction model for surgical duration by extracting features from unstructured surgical planning texts and integrating multimodal data via artificial intelligence technology.Methods The clinical data of 34 614 patients who underwent gynecologic surgeries at West China Second University Hospital,Sichuan University between January 2022 and October 2024 were collected.An embedding-transformer model was constructed to convert surgical planning texts into a one-dimensional numerical feature,referred to as the step feature.The predictive value of the step feature was assessed by comparing the performance improvements of linear regression,random forest,eXtreme Gradient Boosting(XGBoost),support vector regression,K-nearest neighbor regression,and artificial neural network algorithms in two scenarios—with and without the step feature as an input.The out-of-sample prediction accuracy of the models was assessed using mean absolute error(MAE),root mean squared error(RMSE),and R-squared(R2).Furthermore,the model interpretability was examined using SHapley Additive exPlanations(SHAP)values.Results SHAP results showed that the step feature had the highest predictive contribution.Temporal factors in surgical scheduling also influenced gynecological surgery duration.The XGBoost model demonstrated optimal performance on the test set,significantly improving prediction accuracy with a 40.43%increase in R2,while reducing MAE and RMSE by 21.27%and 20.13%,respectively,compared to the baseline model without the step feature.Conclusion The embedding-transformer model developed in this study effectively extracts features from surgical planning texts and enhances the predictive performance of machine learning models.The XGBoost prediction model can assist hospital administrators in implementing more refined management of gynecological surgeries and improving the utilization efficiency of surgical resources.
2.Clinical efficacy of hyperbaric oxygen therapy combined with vacuum sealing drainage on 46 cases with early osteofascial compartment syndrome
Gong CHENG ; Wenqing QU ; Zhilin CAO ; Hao WU ; Kai CHU ; Tongqing ZHANG ; Yong ZHAO ; Guang QU
Chinese journal of nautical medicine and hyperbaric medicine 2020;27(6):654-658
Objective:To investigate the clinical efficacy of hyperbaric oxygen(HBO) combined with vacuum sealing drainage (VSD) in the treatment of 46 patients with early osteofascial compartment syndrome (OCS), and to analyze the value of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) for prognostic prediction.Methods:A total of 46 patients with early OCS admitted to the Department of Orthopedics of Yantai Mountain Hospital from September 2015 to March 2020 were retrospectively analyzed. According to the treatment methods, they were divided into observation group ( n=46) and control group ( n=43). The control group was treated with VSD and conventional symptomatic treatment, while the observation group was treated with HBO on the basis of the treatments of the control group. The clinical efficacy was compared after 3 courses of treatment. The pain was graded before and after treatment by visual analogue scale (VAS); the time of swelling subsiding and length of hospital stay were respectively recorded; the freshness and infection of granulation tissue at the incision site of the affected limb were observed, and primary suture or secondary skin grafting was conducted based on evaluation; enzyme linked immunosorbent assay (ELISA) was applied to measure the levels of serum TNF-α and IL-6 at different time points for the prediction of the development of the disease. Results:After 3 courses of treatment, the effective rate of the observation group (97.8%) was significantly higher than that of the control group (81.4%) ( P<0.05). The secondary skin grafting rate in the observation group (53.5%) was significantly lower than that in the control group (21.7%), and the rate of granulation tissue without infection (80.4%) was significantly higher than that of the control group (51.2%) ( P<0.05). The time of swelling subsiding [(13.14 ±3.42)d] and length of hospital stay [(16.55±3.52)d] in the observation group were significantly lower than those in the control group [time of swelling subsiding: (22.39 ±4.48)d; length of hospital stay: (26.87±5.51)d] ( P<0.05). The VAS scores of the observation group were significantly lower than those of the control group on the 7th, 14th, and 21st days after operation ( P<0.05). The levels of serum TNF-α and IL-6 in the observation group were significantly lower than those in the control group on the 7th and 14th days after operation ( P<0.05), but no significant difference was observed on the 21st day ( P>0.05). Conclusion:HBO combined with VSD in the treatment of early OCS can improve the blood circulation of the affected limb, reduce the incidence of incision infection, promote wound healing, and reduce limb pain, so as to improve the curative effect.
3.Clinical efficacy of hyperbaric oxygen therapy combined with vacuum sealing drainage on 46 cases with early osteofascial compartment syndrome
Gong CHENG ; Wenqing QU ; Zhilin CAO ; Hao WU ; Kai CHU ; Tongqing ZHANG ; Yong ZHAO ; Guang QU
Chinese journal of nautical medicine and hyperbaric medicine 2020;27(6):654-658
Objective:To investigate the clinical efficacy of hyperbaric oxygen(HBO) combined with vacuum sealing drainage (VSD) in the treatment of 46 patients with early osteofascial compartment syndrome (OCS), and to analyze the value of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) for prognostic prediction.Methods:A total of 46 patients with early OCS admitted to the Department of Orthopedics of Yantai Mountain Hospital from September 2015 to March 2020 were retrospectively analyzed. According to the treatment methods, they were divided into observation group ( n=46) and control group ( n=43). The control group was treated with VSD and conventional symptomatic treatment, while the observation group was treated with HBO on the basis of the treatments of the control group. The clinical efficacy was compared after 3 courses of treatment. The pain was graded before and after treatment by visual analogue scale (VAS); the time of swelling subsiding and length of hospital stay were respectively recorded; the freshness and infection of granulation tissue at the incision site of the affected limb were observed, and primary suture or secondary skin grafting was conducted based on evaluation; enzyme linked immunosorbent assay (ELISA) was applied to measure the levels of serum TNF-α and IL-6 at different time points for the prediction of the development of the disease. Results:After 3 courses of treatment, the effective rate of the observation group (97.8%) was significantly higher than that of the control group (81.4%) ( P<0.05). The secondary skin grafting rate in the observation group (53.5%) was significantly lower than that in the control group (21.7%), and the rate of granulation tissue without infection (80.4%) was significantly higher than that of the control group (51.2%) ( P<0.05). The time of swelling subsiding [(13.14 ±3.42)d] and length of hospital stay [(16.55±3.52)d] in the observation group were significantly lower than those in the control group [time of swelling subsiding: (22.39 ±4.48)d; length of hospital stay: (26.87±5.51)d] ( P<0.05). The VAS scores of the observation group were significantly lower than those of the control group on the 7th, 14th, and 21st days after operation ( P<0.05). The levels of serum TNF-α and IL-6 in the observation group were significantly lower than those in the control group on the 7th and 14th days after operation ( P<0.05), but no significant difference was observed on the 21st day ( P>0.05). Conclusion:HBO combined with VSD in the treatment of early OCS can improve the blood circulation of the affected limb, reduce the incidence of incision infection, promote wound healing, and reduce limb pain, so as to improve the curative effect.
4.Traditional Chinese medicine combined with transurethral resection of prostate for benign prostatic hyperplasia
Zhilin DENG ; Fuchang LI ; Yong CHEN ; Jun WANG
Chinese Journal of Primary Medicine and Pharmacy 2011;18(2):157-158
Objective To observe and compare the clinical effect of traditional Chinese medicine (TCM)combined with transurethral resection of prostate(TURP) and simple TURP in treating benign prostatic hyperplasia (BPH). Methods 60 patients with BPH were randomly divided into two groups. The treatment group(n=30) was given the TCM combined TURP and the control group(n = 30) was given TURP alone. The effects were observed.Results Improvement of lower urinary tract symptoms(LUTS), the international prostate symptom score (I-PSS) of the treatment group was better than that of the control group with significant difference (P < 0.01). The time and quantity of bladder irrigation, incidence of bladder spasm, incidence of constipation after operation of the treatment group were less than that of the control group with significant difference(all P <0.05). Catheter retention time,postoperative bleeding, urinary retention were less and had no significant difference between the two groups (all P >0. 05). Conclusion The effect of TCM combined with TURP was significantly superior to that of simple TURP; and adverse reaction after treatment was less than that in the control group.
5.Clinical analysis of capsular perforation in transurethral resection of prostate
Zhilin DENG ; Wei JIANG ; Yong CHEN ; Jun WANG
Chinese Journal of Postgraduates of Medicine 2011;34(23):21-23
Objective To investigate the causes and managements of capsular perforation in transurethral resection of prostate(TURP) for benign prostatic hyperplasia (BPH). Methods Clinical data of 893 cases who received TURP from February 2002 to February 2011 were analyzed retrospectively.Results In 893 cases, capsular perforation in 16 cases, among them, tissue covered perforation in 10 cases, dissociative perforation in 3 cases, perforation under bladder trignne in 3 cases. Six cases occurred with obviously extravasation, 10 cases with transurethral resection syndrome (TURS) or omen of TURS. Two cases were ceased operation and received TURP again after 2 weeks, 2 cases transferred to open surgery suprapubic prostatectomy, 12 cases kept up operation with lower bladder douche pressure. Two cases with postoperatire bleeding underwent open surgery hemostasis cured. All cases were discharged from hospital after recovery. Conclusions The type and extent of capsule perforation must be judged correctly,corresponding treatment must be given, prevention and treatment of TURS must be taken notice of, if capsule perforation occurs when TURP operation in progress. Less haematoma, clearview and normal anatomic structures can decrease the incidence of perforation.
6.Clinical application of percutaneous implantation of ~(125)I seeds for treating malignant tumor
Bin JIA ; Linsun LI ; Xiaolan SHI ; Bo XIA ; Zhilin CHEN ; Yong XIAO ; Darong TAN
Journal of Interventional Radiology 1994;0(04):-
Objective To investigate the therapeutic mechanism of ~(125)I seeds based on physical properties, the significance of therapeutic planning system (TPS), the therapeutic means and the clinical efficacy. Methods Eighteen cases with advanced carcinoma were treated through percutaneous implantation of 125 I for interstitial radiotherapy. Results No serious complications occurred in the patients after radiotherapy associated with apparent improved living quality. Two months after therapy, the tumors had shrunk in different degrees with conspicuous decrease in 12, of which 5 tumors disappeared. Conclusions Short-term efficacy demonstrates that intra-tissue radiotherapy of ~(125)I had significant efficacy for advanced tumors.

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