The Treatise on Cold Pathogenic and Miscellaneous Diseases (Shanghan Zabing Lun) records a unique system of pulse diagnosis, pioneering the " site for taking wrist pulse (Cunkou)-Anterior tibial (Fuyang)-Shaoyin" three-part pulse diagnosis method. This system emphasizes the application of the wrist pulse site, classifying pulse conditions into two major categories, yin and yang, thereby laying a solid foundation for the development of traditional Chinese medicine diagnostics. Studying the pulse theory of Shanghai Zabing Lun is of great significance for understanding, inherting, and developing ZHANG Zhongjing′s medicine and clinical diagnosis. However, owing to the passage of time, the precise meaning of certain pulse conditions described by ZHANG Zhongjing, such as the " shang guanshang" pulse, remains unclear. This article explores the location and clinical significance of the " shangguan shang" pulse as referenced in Treatise on Cold Pathogenic and Miscellaneous Diseases and Synopsis of Golden Chamber (Jingui Yaolue). Through textual research, it investigates this pulse and related ones based on medical texts before the Tang Dynasty, such as Inner Canon of Huangdi (Huangdi Neijing) and Classic of Questioning (Nanjing). The findings indicate that the " shangguan shang" pulse is positioned one division before the Guan pulse site. Further analysis of the clinical significance suggests the existence of a pulse-taking method involving three body regions and nine pulse-taking sites, subdividing the Cun, Guan, and Chi positions into three distinct sections. This pulse diagnostic method enriches the ways of pulse diagnosis, but further exploration and verfication are needed.