1.Current research and future perspectives on oropouche virus
Peijun HE ; Ziyun CHEN ; Tianfeng AN ; Dongsheng CHEN ; Xin CHEN ; Yishan CAI ; Enjiong HUANG ; Lihua MA ; Xiaohua LIU ; Zhenyong REN ; Na JIA
Chinese Journal of Epidemiology 2025;46(8):1513-1518
The oropouche virus (OROV) poses a threat to pregnant women and fetuses, potentially causing fetal neurological defects and even stillbirth, which has caused global attention. OROV is an arthropod-borne virus belonging to the Orthobunyavirus genus in the Bunyavirales order, primarily transmitted by arthropods and causing oropouche fever. This article reviews the etiological characteristics, epidemiological distribution, clinical symptoms, detection methods, and prevention strategies of OROV. OROV is prevalent in Central and South America, with a sharp increase in cases reported in Brazil in 2024. The virus's symptoms resemble those of several other arthropod-borne viral diseases, which can lead to misdiagnosis. Currently, there are no specific drugs or vaccines available, and treatment is mainly supportive. Culicoides paraensis and Culex quinquefasciatus are among the significant vectors of OROV. Furthermore, the article analyzes the distribution of Culex quinquefasciatus in China, highlights the risk of imported cases, proposes targeted prevention and control strategies, and underscores the significance of international cooperation in disease prevention and control.
2.Analysis of the infection status of severe fever with thrombocytopenia syndrome virus in Beijing in 2024
Yulan SUN ; Xiangfeng DOU ; Weijia ZHANG ; Yanwei CHEN ; Fu LI ; Haoyuan JIN ; Zhenyong REN ; Dan LI ; Daitao ZHANG
Chinese Journal of Experimental and Clinical Virology 2025;39(2):136-141
Objective:To analyze the epidemiological characteristics of severe fever with thrombocytopenia syndrome (SFTS) in Beijing in 2024, to investigate the infection status of reservoir hosts, vector organisms, and baseline human populations, and provide a scientific basis for formulating prevention and control strategies.Methods:Epidemiological surveys were conducted on all confirmed cases. Serum samples from healthy populations and reservoir hosts were collected for SFTSV antibody detection. Questing ticks were monitored using the flagging method. Real-time fluorescent quantitative PCR was employed to detect SFTSV in cases, reservoir hosts, and ticks. Positive samples underwent whole-genome sequencing and genetic evolution analysis.Results:In 2024, Beijing reported 15 locally infected cases with 4 deaths. The age of onset ranged from 50 to 80 years (median: 66 years). Cases showed a certain degree of geographical clustering, with June being the peak month of onset. The affected population was predominantly farmers, with a male-to-female ratio of 3∶2. Animal contact history emerged as a significant risk factor alongside tick bites. Parthenogenetic tick populations were identified in Pinggu district, while SFTSV-carrying ticks were detected in endemic areas (Mentougou, Shijingshan, and Fengtai Districts). Viral presence was also confirmed in ticks or dogs from non-endemic areas. Sequencing and phylogenetic analysis revealed stable clustering of strains into two distinct genotypes (A and B). Antibody-positive individuals were identified in healthy populations from non-endemic areas.Conclusions:The incidence of SFTS in Beijing is increasing, with natural viral circulation already established in non-endemic regions. Enhanced surveillance and adjusted prevention strategies are urgently needed.
3.Current research and future perspectives on oropouche virus
Peijun HE ; Ziyun CHEN ; Tianfeng AN ; Dongsheng CHEN ; Xin CHEN ; Yishan CAI ; Enjiong HUANG ; Lihua MA ; Xiaohua LIU ; Zhenyong REN ; Na JIA
Chinese Journal of Epidemiology 2025;46(8):1513-1518
The oropouche virus (OROV) poses a threat to pregnant women and fetuses, potentially causing fetal neurological defects and even stillbirth, which has caused global attention. OROV is an arthropod-borne virus belonging to the Orthobunyavirus genus in the Bunyavirales order, primarily transmitted by arthropods and causing oropouche fever. This article reviews the etiological characteristics, epidemiological distribution, clinical symptoms, detection methods, and prevention strategies of OROV. OROV is prevalent in Central and South America, with a sharp increase in cases reported in Brazil in 2024. The virus's symptoms resemble those of several other arthropod-borne viral diseases, which can lead to misdiagnosis. Currently, there are no specific drugs or vaccines available, and treatment is mainly supportive. Culicoides paraensis and Culex quinquefasciatus are among the significant vectors of OROV. Furthermore, the article analyzes the distribution of Culex quinquefasciatus in China, highlights the risk of imported cases, proposes targeted prevention and control strategies, and underscores the significance of international cooperation in disease prevention and control.
4.Analysis of the infection status of severe fever with thrombocytopenia syndrome virus in Beijing in 2024
Yulan SUN ; Xiangfeng DOU ; Weijia ZHANG ; Yanwei CHEN ; Fu LI ; Haoyuan JIN ; Zhenyong REN ; Dan LI ; Daitao ZHANG
Chinese Journal of Experimental and Clinical Virology 2025;39(2):136-141
Objective:To analyze the epidemiological characteristics of severe fever with thrombocytopenia syndrome (SFTS) in Beijing in 2024, to investigate the infection status of reservoir hosts, vector organisms, and baseline human populations, and provide a scientific basis for formulating prevention and control strategies.Methods:Epidemiological surveys were conducted on all confirmed cases. Serum samples from healthy populations and reservoir hosts were collected for SFTSV antibody detection. Questing ticks were monitored using the flagging method. Real-time fluorescent quantitative PCR was employed to detect SFTSV in cases, reservoir hosts, and ticks. Positive samples underwent whole-genome sequencing and genetic evolution analysis.Results:In 2024, Beijing reported 15 locally infected cases with 4 deaths. The age of onset ranged from 50 to 80 years (median: 66 years). Cases showed a certain degree of geographical clustering, with June being the peak month of onset. The affected population was predominantly farmers, with a male-to-female ratio of 3∶2. Animal contact history emerged as a significant risk factor alongside tick bites. Parthenogenetic tick populations were identified in Pinggu district, while SFTSV-carrying ticks were detected in endemic areas (Mentougou, Shijingshan, and Fengtai Districts). Viral presence was also confirmed in ticks or dogs from non-endemic areas. Sequencing and phylogenetic analysis revealed stable clustering of strains into two distinct genotypes (A and B). Antibody-positive individuals were identified in healthy populations from non-endemic areas.Conclusions:The incidence of SFTS in Beijing is increasing, with natural viral circulation already established in non-endemic regions. Enhanced surveillance and adjusted prevention strategies are urgently needed.
5.VITAMINS AND MINERALS INTAKE FROM DIET AND DIETARY SUPPLEMENT IN BEIJING ADULTS
Yuna HE ; Zhen YANG ; Jun XU ; Yimei SHA ; Zhenyong REN ; Xinghuo PANG
Acta Nutrimenta Sinica 1956;0(02):-
Objective To analyze the contribution of dietary supplements to current vitamin mineral intakes in Beijing,China.Method By stratified cluster sampling method,3992 subjects aged 18y and above in 1440 households were investigated in 6 different regions in Beijing.Results The dietary intake of vitamin and mineral of men was higher than that of women,but the total intake of niacin and vitamin C was lower.Both dietary and total intake of vitamin and mineral in supplement users were higher that those in nonusers.In the group of supplement users,the contribution of supplement to thiamin,riboflavin and calcium intakes was 60% and 70%,47% and 45%,42% and 45% in men and women respectively.The percentage of supplement users who reached the current recommended intakes of vitamins and minerals was higher compared with that of nonusers,about 20 -30 percent higher for vitamin C and calcium.Conclusion The average intakes of vitamin and mineral are improved by using dietary supplements.Dietary supplements should be included in the future nutrition survey in China for improving the accuracy of nutrient’s intake.

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