Purpose To explore the clinicopathological features and endoscopic manifestations of cap polyposis(CP).Methods Clinical,endoscopic,pathological,and follow-up data of 17 cases of CP were collected and ana-lyzed.Results There were 14 males and 3 females,aged 15-67 years,with a mean age of 36.5 years.The disease duration ranged from 2 weeks to 5 years,and most patients(64.7％,11/17)had symptoms for more than l year.The most common clinical manifestation was hematochezia(82.4％,14/17),while constipation was generally absent.En-doscopically,all lesions(100％,17/17)were located in the anal canal and lower rectum.The surface was invariably covered with a thick whitish exudate(100％,17/17),and annular growth was the most frequent pattern(76.5％,13/17).Pathologically,the mucosal layer was almost entirely replaced by granulation tissue,and the surface showed extensive inflammatory necrosis forming a cap-like structure.Conclusion CP predominantly occurrs in the anal canal and lower rectum of young men.The presence of abundant whitish exudate under endoscopy is differential diagnostic value.Complete endoscopic resection followed by pathological examination is required for definitive diagnosis.

Purpose To explore the clinicopathological features and endoscopic manifestations of cap polyposis(CP).Methods Clinical,endoscopic,pathological,and follow-up data of 17 cases of CP were collected and ana-lyzed.Results There were 14 males and 3 females,aged 15-67 years,with a mean age of 36.5 years.The disease duration ranged from 2 weeks to 5 years,and most patients(64.7％,11/17)had symptoms for more than l year.The most common clinical manifestation was hematochezia(82.4％,14/17),while constipation was generally absent.En-doscopically,all lesions(100％,17/17)were located in the anal canal and lower rectum.The surface was invariably covered with a thick whitish exudate(100％,17/17),and annular growth was the most frequent pattern(76.5％,13/17).Pathologically,the mucosal layer was almost entirely replaced by granulation tissue,and the surface showed extensive inflammatory necrosis forming a cap-like structure.Conclusion CP predominantly occurrs in the anal canal and lower rectum of young men.The presence of abundant whitish exudate under endoscopy is differential diagnostic value.Complete endoscopic resection followed by pathological examination is required for definitive diagnosis.

Objective To evaluate the effectiveness and safety of pulsed radiofrequency (PRF) for postherpetic neuralgia (PHN). Methods The database was searched systematically and comprehensively, including PubMed, Cochrane library, Medalink, Embase, CNKI, Wanfang data and VIP data, from database creation to February 15, 2018. Manual retrieval was supplemented. The Cochrane Handbook 5.1 was used to evaluate the studies, and Meta-analysis was performed using RevMan 5.3. Results Seven literature were selected, including 486 patients. The Meta-analysis result showed that pain relief at 48 h, 1 week, 1 month, 3 months and 6 months after PRF was significantly better than that after traditional therapy in patients with PHN ( MD or SMD ＝-1.21,-1.38,-1.46,- 0.99 and- 0.95;95% CI-1.54 to-0.88,-1.58 to-1.17,-1.67 to-1.26,-1.31 to-0.67 and-1.13 to-0.77, P＜0.01). The incidence of short-term complications and adverse reactions was 4.9% (12/243), and the patients were able to relieve himself after 15 d. Conclusions PRF is more effective than traditional treatment for PHN, and the treatment effect and safety is more obvious within 6 months.