Objective To investigate the clinical effects of hyperbaric oxygen (HBO) on chronic cerebral ischemia and its impact on cerebral blood perfusion.Methods One hundred and twenty cases of chronic cerebral ischemia that received treatment in Yantaishan Hospital from July 2015 to July 2018 were enrolled for the study,and in accordance with different treatment methods,they were divided into the control group and the observation group,each consisting of 60 cases.Symptom improvement in vertigo and dizziness was assessed by Eurovertigo Scale and Self-rating Dizziness Scale,and changes in cerebral vascular perfusion were detected by magnetic resonance imaging (MRI) and 3-dimensional arterial spin labeling (ASL) before and after treatment.Results After 8 weeks of treatment,the scores of Eurovertigo Scale in the 2 groups were significantly decreased as compared with those before treatment,and statistical significance could be seen when comparisons were made between the 2 groups (P ＜ 0.01).The scores of Eurovertigo Scale in the observation group (2.2 ±:0.7) were significantly lower than those in the control group (3.0 ± 1.0),with statistical significance (P ＜ 0.05).After 4 to 8 weeks of treatment,the scores of Self-rating scale in the observation group were significantly lower than those in the control group,also with statistical significance (P ＜ 0.05).After 8 weeks of treatment,the r-CBF values of cerebral blood flow in white matter of anterior cerebral watershed,white matter of middle artery and white matter of posterior watershed in both groups were significantly increased as compared with those before treatment,also with statistical significance (P ＜0.01),The r-CBF values in the observation group were significantly higher than those in the control group,and statistical significance could also be noted when comparisons were made between the 2 groups (P ＜ 0.05).Conclusion Comprehensive HBO therapy could improve clinical symptoms of chronic cerebral ischemia and cerebral blood perfusion.For this reason,it was worth further clinical application.

Objective To investigate the clinical effects of hyperbaric oxygen (HBO) on chronic cerebral ischemia and its impact on cerebral blood perfusion.Methods One hundred and twenty cases of chronic cerebral ischemia that received treatment in Yantaishan Hospital from July 2015 to July 2018 were enrolled for the study,and in accordance with different treatment methods,they were divided into the control group and the observation group,each consisting of 60 cases.Symptom improvement in vertigo and dizziness was assessed by Eurovertigo Scale and Self-rating Dizziness Scale,and changes in cerebral vascular perfusion were detected by magnetic resonance imaging (MRI) and 3-dimensional arterial spin labeling (ASL) before and after treatment.Results After 8 weeks of treatment,the scores of Eurovertigo Scale in the 2 groups were significantly decreased as compared with those before treatment,and statistical significance could be seen when comparisons were made between the 2 groups (P ＜ 0.01).The scores of Eurovertigo Scale in the observation group (2.2 ±:0.7) were significantly lower than those in the control group (3.0 ± 1.0),with statistical significance (P ＜ 0.05).After 4 to 8 weeks of treatment,the scores of Self-rating scale in the observation group were significantly lower than those in the control group,also with statistical significance (P ＜ 0.05).After 8 weeks of treatment,the r-CBF values of cerebral blood flow in white matter of anterior cerebral watershed,white matter of middle artery and white matter of posterior watershed in both groups were significantly increased as compared with those before treatment,also with statistical significance (P ＜0.01),The r-CBF values in the observation group were significantly higher than those in the control group,and statistical significance could also be noted when comparisons were made between the 2 groups (P ＜ 0.05).Conclusion Comprehensive HBO therapy could improve clinical symptoms of chronic cerebral ischemia and cerebral blood perfusion.For this reason,it was worth further clinical application.