1.Study on the effect of acupressure and ear acupoint pressure bean on alleviating the adverse reactions of polyethylene glycol electrolyte powder
Meiyun WANG ; Zhener SUN ; Xiayan YANG ; Fang MA
Adverse Drug Reactions Journal 2023;25(7):424-429
Objective:To observe the effect of acupressure and ear acupoint pressure bean on alleviating the adverse reactions of polyethylene glycol electrolyte powder in patients undergoing colonoscopy, and analyze the effect on patients' medication compliance and intestinal cleanliness.Methods:The study was designed as a prospective, single-center, randomized controlled clinical trial. The subjects were selected from patients who planned to undergo colonoscopy in the Endoscopy Center of the Affiliated Hospital of Hangzhou Normal University and were divided into trial group (50 patients) and control group (50 patients) in terms of random number table method. Patients in the control group was given colonoscopy routine nursing, and those in the trial group was treated with acupressure and ear acupoint pressure bean therapy on the basis of routine nursing. The incidence of adverse reactions of polyethylene glycol electrolyte powder, medication compliance (8-item Morisky medication adherence scale), and intestinal cleanliness (Boston bowel preparation scale) in patients were compared between the 2 groups.Results:A total of 100 patients were included initially, 8 fell off during the study, and 92 were finally entered in the analysis, including 46 in the trial group and control group respectively. There were 26 males and 20 females in the trial group, aged (47±6) years with a range from 35 to 56 years, and 25 males and 21 females in the control group, aged (46±6) years with a range from 33 to 57 years. Differences in age, gender, education level, and marital status of patients between the 2 groups were not significant (all P>0.05). The overall incidence of adverse reactions of polyethylene glycol electrolyte powder in the trial group was lower than that in the control group [30.4% (14/46) vs. 65.2% (30/46), χ2=11.152, P=0.001]. Adverse reactions in the trial group included nausea (11 cases), fullness (2 cases), and abdominal pain (1 case), while those in the control group included nausea (17 cases), fullness(5 cases), abdominal pain (4 cases), vomiting (2 cases), anal discomfort and rash (1 case each). The scores of 8-item Morisky medication adherence scale and Boston bowel preparation scale in the trial group were both higher than those in the control group [8 (7, 8) points vs. 6 (6, 6) points, χ2=-7.711, P<0.001; 9 (8, 9) points vs. 7 (7, 7) points, χ2=-6.721, P<0.001]. Conclusion:The addition of acupressure and ear acupoint pressure bean to the routine nursing process in colonoscopy can effectively alleviate the adverse reactions of polyethylene glycol electrolyte powder, and improve patients' medication compliance and intestinal cleanliness.
2.Study on the effect of acupressure and ear acupoint pressure bean on alleviating the adverse reactions of polyethylene glycol electrolyte powder
Meiyun WANG ; Zhener SUN ; Xiayan YANG ; Fang MA
Adverse Drug Reactions Journal 2023;25(7):424-429
Objective:To observe the effect of acupressure and ear acupoint pressure bean on alleviating the adverse reactions of polyethylene glycol electrolyte powder in patients undergoing colonoscopy, and analyze the effect on patients' medication compliance and intestinal cleanliness.Methods:The study was designed as a prospective, single-center, randomized controlled clinical trial. The subjects were selected from patients who planned to undergo colonoscopy in the Endoscopy Center of the Affiliated Hospital of Hangzhou Normal University and were divided into trial group (50 patients) and control group (50 patients) in terms of random number table method. Patients in the control group was given colonoscopy routine nursing, and those in the trial group was treated with acupressure and ear acupoint pressure bean therapy on the basis of routine nursing. The incidence of adverse reactions of polyethylene glycol electrolyte powder, medication compliance (8-item Morisky medication adherence scale), and intestinal cleanliness (Boston bowel preparation scale) in patients were compared between the 2 groups.Results:A total of 100 patients were included initially, 8 fell off during the study, and 92 were finally entered in the analysis, including 46 in the trial group and control group respectively. There were 26 males and 20 females in the trial group, aged (47±6) years with a range from 35 to 56 years, and 25 males and 21 females in the control group, aged (46±6) years with a range from 33 to 57 years. Differences in age, gender, education level, and marital status of patients between the 2 groups were not significant (all P>0.05). The overall incidence of adverse reactions of polyethylene glycol electrolyte powder in the trial group was lower than that in the control group [30.4% (14/46) vs. 65.2% (30/46), χ2=11.152, P=0.001]. Adverse reactions in the trial group included nausea (11 cases), fullness (2 cases), and abdominal pain (1 case), while those in the control group included nausea (17 cases), fullness(5 cases), abdominal pain (4 cases), vomiting (2 cases), anal discomfort and rash (1 case each). The scores of 8-item Morisky medication adherence scale and Boston bowel preparation scale in the trial group were both higher than those in the control group [8 (7, 8) points vs. 6 (6, 6) points, χ2=-7.711, P<0.001; 9 (8, 9) points vs. 7 (7, 7) points, χ2=-6.721, P<0.001]. Conclusion:The addition of acupressure and ear acupoint pressure bean to the routine nursing process in colonoscopy can effectively alleviate the adverse reactions of polyethylene glycol electrolyte powder, and improve patients' medication compliance and intestinal cleanliness.

Result Analysis
Print
Save
E-mail