Objective To discuss the application of one-stop stroke treatment platform in mechanical recanalization of acute anterior circulation large artery occlusive cerebral infarction.Methods The clinical data and imaging materials of patients with acute occlusion of the end of internal carotid artery and M1 segment of the middle cerebral artery,who were admitted to the Zhengzhou University People's Hospital of China within 8 hours of disease onset from August 2018 to December 2020,were collected.All patients received mechanical recanalization of the occluded arteries.A total of 59 patients were treated on a one-stop stroke treatment platform(one-stop group),while other 41 patients were treated in routine operating room(routine group).The baseline data,admission-to-imaging time,imaging-to-femoral artery puncture time,admission-to-femoral artery puncture time,time spent for operation,perioperative complications and 90-day good prognosis rate were compared between the two groups.Results The preoperative median NHISS score of the routine group was 16.0(14.0,20.0)points,which was remarkably higher than 14.0(11.0,16.5)points of the one-stop group,the difference was statistically significant(P=0.003).No statistically significant differences in baseline data,perioperative complications and 90-day good prognosis rate existed between the two groups(all P＞0.05).The median admission-to-imaging time,imaging-to-femoral artery puncture time,admission-to-femoral artery puncture time,and admission-to-reperfusion time in the one-stop group were 15.0(12.0,19.0)min,49.0(36.0,60.0)min,66.0(50.0,82.0)min and 138.0(94.7,161.2)min respectively,which in the routine group were 29.0(24.0,42.0)min,63.0(48.0,85.0)min,99.0(78.0,134.5)min and 161.0(122.5,208.0)min respectively,the differences in the above indexes between the two groups were statistically significant(all P＜0.001).The success rate of vascular recanalization in the one-stop group was 91.5％,which was higher than 70.7％ in the routine group(x2=7.413,P=0.013).Conclusion In mechanical recanalization of acute anterior circulation large artery occlusive cerebral infarction,the use of one-stop stroke treatment platform can significantly shorten the admission-to-femoral artery puncture time and improve the success rate of vascular recanalization.

Objective To discuss theoretical structure model for the scale of recurrent oral ulcer (ROU) with traditional Chinese medicine characteristics; To lay a theoretical foundation for further developing scale. Methods This study followed international patients reported outcome (PRO) scale development specification, combined TCM theories, including the theory of mouth dominate and five internal organs correlation, uniformed spirit and body, correspondence between human and the universe, seven emotions, constructed theoretical structure of PRO scale of ROU. Results The theoretical structure of PRO scale of ROU included four major areas as physiology, psychology, independence, and society and nature. Conclusion Theoretical model of PRO scale of ROU laies the foundation and provides the oretical guidance for the formulation of PRO scale of the ROU.