As a pediatric radiation oncologist, it is necessary to master and evaluate the sedative/anesthesia indications, adverse reactions and solutions and deliver whole-course management of sedation/anesthesia in pediatric radiotherapy under sedation. Although significant progress has been made in sedation/anesthesia, the psychological stress and family burden of sedation/anesthesia still exist. There is still great research potential in the field of investigating effective nonpharmacological interventions to reduce sedation/anesthesia use. In this article, the issues and challenges of sedative management and complications of pediatric radiotherapy and interventions for reducing sedation/anesthesia of radiotherapy were reviewed.

As a pediatric radiation oncologist, it is necessary to master and evaluate the sedative/anesthesia indications, adverse reactions and solutions and deliver whole-course management of sedation/anesthesia in pediatric radiotherapy under sedation. Although significant progress has been made in sedation/anesthesia, the psychological stress and family burden of sedation/anesthesia still exist. There is still great research potential in the field of investigating effective nonpharmacological interventions to reduce sedation/anesthesia use. In this article, the issues and challenges of sedative management and complications of pediatric radiotherapy and interventions for reducing sedation/anesthesia of radiotherapy were reviewed.

Objective:To compare the dosimetry of three-dimensional conformal radiotherapy (3D-CRT), intensity modulated radiotherapy (IMRT) and simplified intensity modulated radiotherapy (sIMRT) for hepato-cellular cancer, in order to put forward the best radiation therapy plan. Methods:10 patients with hepatocellular carcinoma were designed 4 fields radiotherapy plan of 3D-CRT, IMRT and sIMRT, prescribed dose 50 Gy/20f, compared the target dose of homogeneity index (HI) and conformal index, monitor unit (MU), the dose of organ at risk (OAR) of the 3 different radiotherapy techniques. Results: Compared sIMRT respectively with 3DCRT and IMRT, target optimum conformal index IMRT was the optimal, sIMRT was the second, and 3D-CRT was the worst. The differences were statistically significant among them (t=4.95, t=4.32;P<0.05). Target homogeneity index IMRT was the optimal, sIMRT was the second, and 3D-CRT was the worst. The differences were statistically significant among them (t=3.42, t=4.02;P<0.05 statistically significant). The low dose irradiation area of normal liver, time of therapy, the child field number, the total MU and the protection of OAR:3D-CRT