1.Observation of curative effect of Qiju Dihuang pill combined with fluorometholone eye drops on dry eye disease due to Yin deficiency of liver and kidney
Chunli CHANG ; Zeqin CHEN ; Quanbao LIU ; Yanfen SHENG
Tianjin Medical Journal 2025;53(5):547-551
Objective To investigate the efficacy of Qiju Dihuang pill combined with fluorometholone eye drops on dry eye disease(DED)due to Yin deficiency of liver and kidney and its impact on the ocular surface function of patients.Methods Ninety-two patients with DED admitted to our hospital from April 2021 to May 2024 were gathered and assigned into two groups using a random number table method,with 46 patients in each group.The conventional group was treated with fluorometholone eye drops,while the combination group was treated with Qiju Dihuang pills on the basis of the conventional group.The efficacy,tear film break up time(TBUT),length of tear infiltration,corneal fluorescein staining(FLS)and ocular surface disease index(OSDI)of DED patients were compared between the two groups,and adverse reactions were evaluated.Results After treatment,the length of TBUT and tear infiltration were significantly increased in the two groups(P<0.05),OSDI and FLS scores were significantly decreased(P<0.05),and changes were more significant in the combined group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).The efficacy of the combination group was 91.30%(42/46),which was higher than that of the conventional group,76.09%(35/46)(P<0.05).Conclusion The combination of Qiju Dihuang pill and flumilone eye drops has good therapeutic effect for patients with DED of Yin deficiency of liver and kidney.
2.Observation of curative effect of Qiju Dihuang pill combined with fluorometholone eye drops on dry eye disease due to Yin deficiency of liver and kidney
Chunli CHANG ; Zeqin CHEN ; Quanbao LIU ; Yanfen SHENG
Tianjin Medical Journal 2025;53(5):547-551
Objective To investigate the efficacy of Qiju Dihuang pill combined with fluorometholone eye drops on dry eye disease(DED)due to Yin deficiency of liver and kidney and its impact on the ocular surface function of patients.Methods Ninety-two patients with DED admitted to our hospital from April 2021 to May 2024 were gathered and assigned into two groups using a random number table method,with 46 patients in each group.The conventional group was treated with fluorometholone eye drops,while the combination group was treated with Qiju Dihuang pills on the basis of the conventional group.The efficacy,tear film break up time(TBUT),length of tear infiltration,corneal fluorescein staining(FLS)and ocular surface disease index(OSDI)of DED patients were compared between the two groups,and adverse reactions were evaluated.Results After treatment,the length of TBUT and tear infiltration were significantly increased in the two groups(P<0.05),OSDI and FLS scores were significantly decreased(P<0.05),and changes were more significant in the combined group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).The efficacy of the combination group was 91.30%(42/46),which was higher than that of the conventional group,76.09%(35/46)(P<0.05).Conclusion The combination of Qiju Dihuang pill and flumilone eye drops has good therapeutic effect for patients with DED of Yin deficiency of liver and kidney.
3.Discussion of Hp(3) calibration with two thermoluminescent dosimeters in the same standard X-ray RQR radiation field
Wenyan LI ; Guiying ZHANG ; Lantao LIU ; Dongsheng NIU ; Zeqin GUO ; Zhichao WANG ; Hua TUO ; Heyan WU ; Tingting XIA ; Nini CHU ; Jichuan LAI ; Jiaojiao CHEN
Chinese Journal of Radiological Health 2024;33(3):318-322
Objective To compare Hp(3) calibration with a homemade (A) thermoluminescent dosimeter (TLD) and an imported (B) TLD in a standard X-ray RQR radiation field, to explore the different responses of A and B, and to provide foundation for the calibration of Hp(3). Methods A column mode was selected. Hp(3) calibration was performed using A and B in a standard X-ray RQR radiation field in the Secondary Standard Dosimetry Laboratory, National Institute for Radiological Protection, China Center for Disease Control and Prevention. Angle response, energy response, and linear response were calibrated with RQR4 (60 kV), RQR7 (90 kV), and RQR9 (120 kV), respectively. Results In terms of angle response, the calibration results of A were relatively high, while the calibration results of B were relatively low. In terms of energy response, the calibration results showed a similar pattern to angle response. In terms of linear response, the calibration results of both A and B were satisfactory. Conclusion Both A and B can be used for normal calibration of Hp(3) in a standard X-ray RQR radiation field. However, in actual monitoring, attention should be paid to the energy and angle response values of TLDs.
4.Advancements in the mechanism of electroa-cupuncturein improvinglearning-memory ;ability
Zeqin CHEN ; Bo DONG ; Li HUANG ; Xuke HAN ; Shifen XU
International Journal of Traditional Chinese Medicine 2016;38(10):952-955
This paper reviewed the studies on the effect of electroacupuncture in improving learning and memory functions in the past 10 years. It showed an overview of the mechanisms that how acupuncture worksed: promoting synaptic plasticity, regulation of microvascular injury and oxidative stress; slowing down the progress of brain cell apoptosis, inhibition of inflammatory response;regulating neurotransmitter release and protecting the ultrastructure of neurons. In addition, this paper puts forth the problems which left in the current studies.
5.VEGF expression in Reinke's edema and its clinical significance
Chaofeng XIE ; Zeqin ZHENG ; Qinqing HU ; Qinquan JI ; Xuelin WANG ; Yingfang CHEN
Chinese Journal of Primary Medicine and Pharmacy 2009;16(4):-
Objective To explore the etiopathogenisis of Reinke's edema. Methods To detect 15 samples of Reinke's edema of vocal cord mucosal and 5 samples of common vocal cord mucosal with S-P immunohistochemical method. Then to observe the effect of immunity class under the light microscope. To detect the expression of the VEGF and the production of the blood capillary in the sample of Reinke's edema of vocal cord mucosal with immunohisto-chemical method. Results There are 12 effects of sex in the 15 samples of Reinke's edema of vocal cord mucosal. There are effects of feminine in the 5 samples of common. Conclusion The main etiopathogenisis of Reinke's edema is that blood vessel grew ad libitum, the permeability of blood vessel increase and oxygen lack partly.
6.The expression and biological significance of methallothionein in thyroid diseases
Linxing CHEN ; Shenren CHEN ; Zeqin CHEN ; Junwei WU ; Hua HUAN
Chinese Journal of Laboratory Medicine 2003;0(09):-
Objective To research the expression and biological significance of methallothionein(MT) in different thyroid diseases(TDs).Methods The expression of MT was observed by immunohistochemical stain and the difference among TDs was compared.Results MT was completely expressed in all TDs. Expression of MT was 87.60?9.20 in thyroid carcinoma,significantly higher than that(62.20?12.40) in thyroid adenoma, that(61.10?13.20) in Graves′ disease and that(58.50?10.60) in Hashimoto′ thyroiditis (P

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