Spontaneous bacterial peritonitis (SBP) is a common complication of cirrhotic ascites, and has a high incidence rate, rapid progression, and a high fatality rate. At present, there are no uniform diagnostic criteria for SBP at home and abroad. Some patients do not have the typical clinical symptoms of SBP, and therefore, missed diagnosis might occur in such patients and the patient′s condition might be delayed. This article reviews the advances in the diagnosis, pathogenesis, and treatment of SBP, in order to provide a reference to clinical physicians, increase the diagnostic rate of SBP, reduce clinical fatality rate, and improve patients′ prognosis.

Objective To analyze suicide scene, damage morphology and case investigation of mountain type scenic spot for giving the references to determine the nature of cliff suicide cases. Methods The suicide cases collected from 2002 to 2012 in scenic spot of Mount Huangshan. The age, gender, native place, case location, damage inspection and behavior were analyzed. Results In the 52 suicide cases, the suicide rate of male was higher than that of female. The numbers from other provinces were higher than that of local province. The age was mainly range from 19 to 50. The time of suicide cases mostly happened between 16:00 to 24:00. The major damage was compound injury with varying degrees of traumatic brain injury, organic injury of pleuroperitoneal cavity and surface bruise and scratch. Conclu-sion In order to determine the nature of cliff suicide cases, it needs to work synthetically in the investi-gation of crime scene and interview.

The interferon is a commonly used drug which is used to treat viral hepatitis. Due to its significant role in the regulation of immune system,it can conduce to inflammatory bowel diseases,such as ulcerative colitis,Crohnˊs disease,and ischemic colitis. Interferon-related ulcerative colitis is more common, generally occurs from two weeks to several years after interferon therapy,the patients complain of abdominal pain and diarrhea,mucus stool is the main manifestation. A total colonoscopy shows diffuse mucosal edema, ulcer,and hyperemia. The patients are treated with mesalazine,sulfasalazine or glucocorticoids. Some patients may continue interferon therapy after the symptoms improved. Interferon-related Crohn's disease is rare and the prognosis is poor. Interferon-related ischemic colitis lesions generally are confined to the descending colon,long-term ulcers,mucosal edema and erosion bleeding. The symptoms are relieved within 2 weeks after interferon discontinuation and symptomatic therapy. Then interferon therapy can be continued.

The interferon is a commonly used drug which is used to treat viral hepatitis. Due to its significant role in the regulation of immune system,it can conduce to inflammatory bowel diseases,such as ulcerative colitis,Crohnˊs disease,and ischemic colitis. Interferon-related ulcerative colitis is more common, generally occurs from two weeks to several years after interferon therapy,the patients complain of abdominal pain and diarrhea,mucus stool is the main manifestation. A total colonoscopy shows diffuse mucosal edema, ulcer,and hyperemia. The patients are treated with mesalazine,sulfasalazine or glucocorticoids. Some patients may continue interferon therapy after the symptoms improved. Interferon-related Crohn's disease is rare and the prognosis is poor. Interferon-related ischemic colitis lesions generally are confined to the descending colon,long-term ulcers,mucosal edema and erosion bleeding. The symptoms are relieved within 2 weeks after interferon discontinuation and symptomatic therapy. Then interferon therapy can be continued.

Objective To identify the effect of glucose regulating protein 75 expression in PC12 cells under glucose deprivation.Methods MTT method was used to monitor the cell viability.The leakage of LDH was represented as the index of cell injury.Flow cytometry was applied for cell cycle analysis,apoptosis and necrosis.Using RT-PCR detected and quantified mRNA.Western blot to measure relative amounts of the protein.Results Cell viability decreased and the LDH leakage increased.While the treated PC12 cells had two main forms of apoptosis and necrosis.GRP75 mRNA and protein levels were upregulated.Conclusion GRP75 has protective function during glucose deprivation.