Levothyroxine anaphylaxis is a rare yet severe adverse reaction to exogenous levothyroxine. While levothyroxine desensitization is commonly employed, its direct application in patients with severe shock poses considerable risks. Omalizumab may offer a potential adjunctive approach to induce tolerance to levothyroxine. We reported a case of a 30-year-old female with a history of thyroid papillary carcinoma who developed anaphylactic shock following oral administration of 50 μg levothyroxine daily after surgery. High serum level of immunoglobulin E (IgE 99.2 kU/L) and positive intradermal tests to all brands of levothyroxine available in China confirm a type Ⅰ hypersensitivity reaction. Several reports have proven the role of omalizumab in desensitization protocol in IgE-mediated diseases; therefore, she was pretreated with three courses of omalizumab (150 mg intradermal injection every four weeks). She then successfully completed oral levothyroxine desensitization and tolerated treatment dose of levothyroxine without experiencing allergic symptoms along with normalization of thyroid function. Further research is warranted to assess its potential as a standard treatment in difficult-to-treat levothyroxine hypersensitivity.

Objective: To identify the social ecological factors of individual, family, and physical environments for affecting the development of fundamental motor skills (FMS) among overweight and obese children, so as to provide a basis for the future intervention design and policy making. Methods: From March to April 2022, one public primary school was recruited from each of the 4 main urban areas in Shijiazhuang, and a total of 425 children in schools were recruited for data collection including individual, family, physical environmental factors, by using a stratified cluster random sampling approach. Test of Gross Motor Development-Third Edition (TGMD-3) was used to evaluate children s FMS. Hierarchical linear regression model was employed to analysis the associations between the 18 factors for individual, family, and physical environments, and the FMS of overweight and obese children. Results: Individual level including the child s age, gender and sleep duration, and family level including high family economic level, parental support for physical activity, and the physical activity environment surrounding the family and community were consistent predictors of movement skills ( B =0.422, -1.972, 0.014, 0.045, 1.042, 0.827, 1.898), ball skills ( B =0.858, 3.953, 0.013, 0.092, 2.141, 1.173, 1.954), and composite skills ( B =1.305, 1.915, 0.028, 0.142, 3.091, 1.962, 3.879) among overweight and obese children ( P <0.05). Furthermore, child s body mass index (BMI), moderate to vigorous physical activity, perceived motor competence, pleasure of exercise,as well as BMI and physical activity levels of their primary caregiver, were associated with different types of FMS ( P <0.05). Individual, family, and physical environmental factors had moderate to high predictive explanatory power for FMS among overweight and obese children ( 2=0.69, 0.75, 0.93, P <0.01). Conclusions The factors influencing the development of FMS in overweight and obese children are multifaceted, with individual, family, and physical environment factors all playing significant roles.Corresponding measures should be actively taken to improve FMS in overweight and obese children.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.