Purpose: This study aimed to evaluate changes in anterior segment morphology and intraocular pressure (IOP) in patients with acute angle-closure glaucoma (AACG) following early phacoemulsification, using Scheimpflug-Placido disc tomography. Methods: In this retrospective cohort study, 32 eyes of 32 phakic patients diagnosed with AACG and referred to a tertiary hospital between 2021 and 2023 were included. After medical stabilization of IOP and inflammation, all patients underwent cataract surgery within 1 month of the acute attack. Anterior segment parameters were assessed using Scheimpflug-Placido disc tomography before and 1 month after surgery. Paired t-tests were used for statistical analysis. Results: The mean age of patients was 65.76 ± 9.63 years. Postoperatively, best-corrected visual acuity improved significantly (preoperative, 0.81 ± 0.92 logMAR; postoperative, 0.18 ± 0.30 logMAR; p < 0.01). Mean IOP decreased by 22.80 ± 3.45 mmHg (p < 0.01). Significant increases were observed in iridocorneal angle (from 24.62° ± 9.59° to 46.20° ± 10.93°), anterior chamber depth (from 1.34 ± 0.65 to 3.02 ± 0.82 mm), and anterior chamber volume (from 98.01 ± 28.62 to 145.87 ± 27.27 mm3), all with p < 0.01. Central corneal thickness decreased slightly but significantly (from 579.80 ± 47.48 to 556.80 ± 47.29 μm, p = 0.03). Conclusions Early lens extraction in AACG significantly improves anterior segment parameters and lowers IOP. Scheimpflug- Placido disc tomography is a useful noninvasive tool to quantify these changes.

PURPOSE: The purpose of this study is to evaluate the prognostic role of preoperative neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) and the need for para-aortic lymphadectomy in patients with primary fallopian tube carcinoma (PFTC). MATERIALS AND METHODS: Ninety-one patients with a diagnosis of PFTC were identified through the gynecologic oncology service database of six academic centers. Clinicopathological, surgical, and complete blood count data were collected. RESULTS: In univariate analysis, advanced stage, suboptimal surgery, and NLR > 2.7 were significant prognostic factors for progression-free survival, whereas in multivariate analysis, only advanced stage and suboptimal surgery were significant. In addition, in univariate analysis, cancer antigen 125 > or = 35 U/mL, ascites, advanced stage, suboptimal surgery, NLR > 2.7, PLR > 233.3, platelet count > or =400,000 cells/mm3, staging type, and histological subtype were significant prognostic factors for overall survival (OS); however, in multivariate analysis, only advanced stage, suboptimal surgery, NLR > 2.7, and staging type were significant. Inclusion of pelvic and para-aortic lymphadenectomy in surgery showed significant association with longer OS, with a mean and median OS of 42.0 months and 35.5 months (range, 22 to 78 months), respectively, vs. 33.5 months and 27.5 months (range, 14 to 76 months), respectively, for patients who underwent surgery without para-aortic lymphadenectomy (hazard ratio, 3.1; 95% confidence interval, 1.4 to 5.7; p=0.002). CONCLUSION: NLR (in both univariate and multivariate analysis) and PLR (only in univariate analysis) were prognostic factors in PFTC. NLR and PLR are inexpensive and easy tests to perform. In addition, patients with PFTC who underwent bilateral pelvic and para-aortic lymphadenectomy had longer OS.
Ascites ; Blood Cell Count ; Blood Platelets* ; Diagnosis ; Disease-Free Survival ; Fallopian Tubes* ; Female ; Humans ; Lymph Node Excision* ; Lymphocytes* ; Multivariate Analysis ; Neutrophils* ; Platelet Count