Building a harmonious doctor-patient relationship reflects the people’s expectations and society’s aspirations. It is an important factor related to the well-being of the population and the implementation of the healthy China strategy. The theory of intersubjectivity focuses on responding to the relationship between subjects. Based on the principles of interactivity， liveliness， and dialogue rationality， it highlights equal interaction， mutual understanding， and effective dialogue between subjects. Applying the intersubjectivity theory to the construction of a harmonious doctor-patient relationship can help to break the behavioral paradigm of the doctor-patient subject-object dichotomy， highlighting the true freedom of the doctor-patient dual subjects. From the perspective of intersubjectivity， a harmonious doctor-patient relationship is generated from intersubjective behavior， facilitated by pre-understanding between subjects， and realized through effective dialogue between subjects. In the real world， the obfuscation of subjective rationality， the division of cognitive structure， and the uneven demands of interest between doctors and patients eliminate the inherent mechanisms of a harmonious doctor-patient relationship. This leads to multiple practical dilemmas， such as a “subject-object” one-dimensional thinking mode， a “professional-life” structural cognitive difference， and “reason-sensibility” dislocation dialogue styles presented between doctors and patients. Promoting the transformation of doctor-patient interactive thinking form， the integration of their communication perspectives， and the enhancement of dialogue skills can help to achieve mutual understanding in cognition， mutual trust and empathy in emotions， and harmonious alignment in actions. Therefore， to address these dilemmas， this paper proposed a path by embedding intersubjectivity theory， strengthening bidirectional doctor-patient interaction， emphasizing doctor-patient illness narratives， bridging doctor-patient cognitive differences， focusing on improving subjective competencies， and enhancing doctor-patient humanistic care.

OBJECTIVE:To study in vitro bacteriostatic activity of the extracts from Miao medicine Polygonum runcinatum. METHODS:Using chloramphenicol and fluconazole as positive control,the inhibitory effects of water extract,95％ ethanol extract and its ethyl acetate and n-butanol fraction on 9 kinds of strains were determined by cup plate method, such as Staphylococcus aureus,Escherichia coli,Shigella flexneri,Salmonella typhi,Bacillus subtilis,Pseudomonas aeruginosa,type B Hemolytic streptococcus,Candida albicans and Cryptococcus neoformans. The parts with bacteriostatic activity and trial strains sensitive to drug were screened. Micro-broth dilution method and agar culture medium plate method were used to determine MIC and MBC of 95％ ethanol extract and its fractions of P. runcinatum to sensitive strains. RESULTS:The water extract of P. runcinatum almost had no inhibitory effect. 95％ ethanol extract showed different degrees of bacteriostatic activity to strains;bacteriostatic effects of it to 6 kinds of bacteria as S. typhi was better than that of type B H. streptococcus and 2 kinds of fungus. The ethyl acetate and n-butanol fraction of 95％ ethanol extracts showed good bacteriostatic effect and the ethyl acetate fraction had stronger effect,while all the fractions of 95％ ethanol extracts showed no inhibitory effect on fungus. MIC and MBC of 95％ethanol extract to above 6 kinds of bacteria were 6.25-12.5 and 12.5-25 mg/mL,respectively;MIC and MBC of ethyl acetate fraction were 3.13-6.25, 6.25-12.5 mg/mL; MIC and MBC of n-butanol fraction were 6.25-12.5, 12.5-25 mg/mL. CONCLUSIONS:95％ ethanol extract,ethyl acetate and n-butanol fractions of Miao medicine P. runcinatum have obvious in vitro bacteriostatic activity to 6 common bacterias as S. typhi.