Objective To investigate the therapeutic effects of intestinal electrophysiology pacing on functional constipation (FC) of naval afloat personnel during prolonged voyage.Methods A total 61 patients with FC were randomly divided into 2 groups,the intestinal electrophysiology pacing group (n =30) and the drug group (n =30).Electric current with multi-wave sine pulse was used to induce intestinal electrophysiology pacing on the body surface.The subjects in the drug group were treated with mosapride tablets,and evaluations were made on the improvement of various symptoms both before and 2 weeks after treatment.Results After treatment with intestinal electrophysiology pacing,the scores of such clinical symptoms as defecation interval time,straining effort,sensation of anorectal blockage,stool consistence,bloating and total scores were all significantly decreased,as compared with those before therapy (P ＜ 0.05).When compared with those of the mosapride group,the treatment with intestinal electrophysiology pacing displayed significant improvement in total clinical symptoms (P ＜ 0.01),shortening of defecation interval time and alleviation of straining effort (P ＜ 0.05).Intestinal electrophysiology pacing treatment was particularly suitable to those confirmed FC patients before voyage(P ＜ 0.05).However,in those newly developed FC patients,there were no significant differences in therapeutic effects,when comparisons were made between the 2 groups (P ＞ 0.05).Conclusions Treatment with intestinal electrophysiology pacing could remarkably improve the clinical symptoms of FC patients when compared with mosapride treatment during prolonged voyage,and its superiority was especially remarkable in those FC patients who had been diagnosed to have FC before voyage.

Objective To investigate the therapeutic effects of intestinal electrophysiology pacing on functional constipation (FC) of naval afloat personnel during prolonged voyage.Methods A total 61 patients with FC were randomly divided into 2 groups,the intestinal electrophysiology pacing group (n =30) and the drug group (n =30).Electric current with multi-wave sine pulse was used to induce intestinal electrophysiology pacing on the body surface.The subjects in the drug group were treated with mosapride tablets,and evaluations were made on the improvement of various symptoms both before and 2 weeks after treatment.Results After treatment with intestinal electrophysiology pacing,the scores of such clinical symptoms as defecation interval time,straining effort,sensation of anorectal blockage,stool consistence,bloating and total scores were all significantly decreased,as compared with those before therapy (P ＜ 0.05).When compared with those of the mosapride group,the treatment with intestinal electrophysiology pacing displayed significant improvement in total clinical symptoms (P ＜ 0.01),shortening of defecation interval time and alleviation of straining effort (P ＜ 0.05).Intestinal electrophysiology pacing treatment was particularly suitable to those confirmed FC patients before voyage(P ＜ 0.05).However,in those newly developed FC patients,there were no significant differences in therapeutic effects,when comparisons were made between the 2 groups (P ＞ 0.05).Conclusions Treatment with intestinal electrophysiology pacing could remarkably improve the clinical symptoms of FC patients when compared with mosapride treatment during prolonged voyage,and its superiority was especially remarkable in those FC patients who had been diagnosed to have FC before voyage.

Objective To investigate the prophylactic effects of pancreatic duct stenting (PDS) combined with non-storied anti-inflammatory drug (NSAID) on post endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) in difficult bile duct cannulation .Methods One hundred and eight patients who experienced difficult bile duct cannulation during hospitalization from January 2012 to November 2016 in the Department of Gastroenterology of the hospital were enrolled for the study .The patients were ran-domly divided into 4 groups:i.e.Group A that underwent simple PDS , Group B that received NSAID , Group C that were treated with PDS combined with NSAID and Group D that had routine ERCP without preventive measures for PEP .The levels of serum amylase be-fore surgery, 4 and 24 hours after ERCP were observed closely .The scores of abdominal pain were evaluated by VAS method , and the levels of serum amylase , the rate of post ERCP and scores of abdominal pain after ERCP were compared between the 4 groups.Results Four hours after ERCP, serum amylase levels of group B and group C were all significantly lower that those of group D (P<0.05). Serum amylase levels of group A, B and C 24 hours after ERCP were all significantly lower that those of group D (P<0.05).The rate of PEP 24 hours after ERCP for group A and C was 0%, which was obviously lower than that of group D (7.4%)(P<0.05).The VAS scores of various groups 4 and 24 hours after ERCP were significantly higher than that before ERCP (P<0.05).The VAS scores of groups B and C 4 and 24 hours after ERCP were all significantly higher than that of group D (P<0.05), and the VAS scores of group B 4 and 24 hours after ERCP was obviously lower than that of group A (P<0.05).Only at hour 24 after ERCP, the VAS pain scores of group A were higher than that of group D (P<0.05).Conclusion After ERCP, pancreatic duct stenting combined with non-storied anti-inflammatory drug could reduce the rates of hyperamylasemia and PEP , as well as the scores of abdominal pain scores after ERCP, and also could effectively prevent the incidence of pancreatitis after PEP .

Objective To investigate the incidence of infectious diseases among the naval shipboard personnel during prolonged deployment at sea and the therapeutic effects.Methods The constitution ratio of infectious diseases among the ship crew during prolonged deployment at sea was calculated and morbidity rates of various infectious diseases at different stages of deployment were compared,and the therapeutic effects of different antibiotics were carefully evaluated.Results During the whole course of prolonged deployment at sea,the constitution ratio of infectious diseases from high percentage to low percentage was respiratory tract infection(65.61％),gastrointestinal tract infection (32.01％),urinary system infection (1.19％) and paronychia(1.19％).The morbidity of gastrointestinal tract infection during the middle stage of deployment was significantly higher than those of the early and late stages.The morbidity of respiratory tract infection during the middle and late stages of deployment was significantly higher than that of the early stage.During the middle and late stages,the cure rate of azithromycin to non-viral respiratory tract infection was significant higher that of cefuroxime.Conclusions Both respiratory tract infection and gastrointestinal tract infection were all commonly seen during prolonged deployment at sea.Significant differences could be noted in the morbidity of respiratory tract infection and respiratory tract infection at different stages of deployment.The therapeutic effect of azithromycin was obviously superior to cefuroxime in the treatment of non-viral respiratory tract infection during the middle and late stages of prolonged deployment at sea.

Objective To investigate the incidence of infectious diseases among the naval shipboard personnel during prolonged deployment at sea and the therapeutic effects.Methods The constitution ratio of infectious diseases among the ship crew during prolonged deployment at sea was calculated and morbidity rates of various infectious diseases at different stages of deployment were compared,and the therapeutic effects of different antibiotics were carefully evaluated.Results During the whole course of prolonged deployment at sea,the constitution ratio of infectious diseases from high percentage to low percentage was respiratory tract infection(65.61％),gastrointestinal tract infection (32.01％),urinary system infection (1.19％) and paronychia(1.19％).The morbidity of gastrointestinal tract infection during the middle stage of deployment was significantly higher than those of the early and late stages.The morbidity of respiratory tract infection during the middle and late stages of deployment was significantly higher than that of the early stage.During the middle and late stages,the cure rate of azithromycin to non-viral respiratory tract infection was significant higher that of cefuroxime.Conclusions Both respiratory tract infection and gastrointestinal tract infection were all commonly seen during prolonged deployment at sea.Significant differences could be noted in the morbidity of respiratory tract infection and respiratory tract infection at different stages of deployment.The therapeutic effect of azithromycin was obviously superior to cefuroxime in the treatment of non-viral respiratory tract infection during the middle and late stages of prolonged deployment at sea.

Objective To investigate the treatment method and effect of intensive early fluid resuscitation on the patients with severe acute pancreatitis ( SAP) in acute reaction stage .Methods Fifty-eight patients with SAP treated in the hospital from Aug .2008 to Mar.2010 were randomly divided into the treatment group (n=30) and the control group (n=28).The patients in the former group were given intensive early fluid resuscitation , either with hydroxyethylstarch and an increased amount of colloidal fluid or occasionally with a certain amount of plasma and albumin .Physiological saline and/or balanced salt solution were used as crystal fluid , with a ratio of 1∶2-1∶1.The patients in the latter group were supplemented or treated with an effective circulating blood volume and electrolyte im -balance correction .They were daily infused with a certain amount of plasma and albumin .Analyses were made on such reactions as re-spiratory failure , renal insufficiency and cardiac dysfunction in the acute reaction stage in patients with SAP .Results With regard to the incidence of complications during the acute reaction stage for the patients of the 2 groups, the incidence of respiratory failure , renal insufficiency and cardiac dysfunction in the patients of the treatment group was significantly lower than that in the patients of the control group, with statistical significance(P<0.05).With regard to the amount of daily fluid infusion for the groups during the acute reaction stage, the amount of infusion for the treatment group was significantly lower than that for the control group , with statistical significance (P<0.05).Conclusion Effective and active early fluid resuscitation during the acute reaction stage in SAP patients could decrease the incidence of complications .The supplementation of Hydroxyethylstarch and the increase in the ratio of colloidal fluid could produce better resuscitative effects on patients with SAP .

Objective To investigate the incidence of non-infectious diseases at different stages of a prolonged escort missiononboard the frigate.Methods The constituent ratio of non-infectious diseases occurred at different stages of a prolonged escort missionby a certain frigate was calculated,and the incidence of various non-infectious diseases at different stages was compared accordingly.Results For non-infectious diseases occurred during the whole course of the mission,the top 3 non-infectious diseases were lumbarmuscle strain,insomnia and motion sickness.Then came dermatitis,dental ulcer,xerophthalmia,trauma and cardiovascular diseases.The onset stages (early,middle and late stages)of various non-infectious diseases were different from one another.The incidence oflumbar muscle strain,insomnia,dermatitis,dental ulcer and xerophthalmia at late stage of the mission was significantly higher than thatat the early stage(P <0.01),and the incidence of motion sickness at the early stage was significantly higher than that at late stage(P <0.01).Conclusion With the extension of the escort mission,the incidence of lumbar muscle strain,insomnia,dermatitis,dentalulcer and xerophthalmia increased,while the incidence of motion sickness decreased.

Objective To investigate the treatment method and effect of intensive early fluid resuscitation on the patients with severe acute pancreatitis ( SAP) in acute reaction stage .Methods Fifty-eight patients with SAP treated in the hospital from Aug .2008 to Mar.2010 were randomly divided into the treatment group (n=30) and the control group (n=28).The patients in the former group were given intensive early fluid resuscitation , either with hydroxyethylstarch and an increased amount of colloidal fluid or occasionally with a certain amount of plasma and albumin .Physiological saline and/or balanced salt solution were used as crystal fluid , with a ratio of 1∶2-1∶1.The patients in the latter group were supplemented or treated with an effective circulating blood volume and electrolyte im -balance correction .They were daily infused with a certain amount of plasma and albumin .Analyses were made on such reactions as re-spiratory failure , renal insufficiency and cardiac dysfunction in the acute reaction stage in patients with SAP .Results With regard to the incidence of complications during the acute reaction stage for the patients of the 2 groups, the incidence of respiratory failure , renal insufficiency and cardiac dysfunction in the patients of the treatment group was significantly lower than that in the patients of the control group, with statistical significance(P<0.05).With regard to the amount of daily fluid infusion for the groups during the acute reaction stage, the amount of infusion for the treatment group was significantly lower than that for the control group , with statistical significance (P<0.05).Conclusion Effective and active early fluid resuscitation during the acute reaction stage in SAP patients could decrease the incidence of complications .The supplementation of Hydroxyethylstarch and the increase in the ratio of colloidal fluid could produce better resuscitative effects on patients with SAP .

Objective To investigate the incidence of non-infectious diseases at different stages of a prolonged escort missiononboard the frigate.Methods The constituent ratio of non-infectious diseases occurred at different stages of a prolonged escort missionby a certain frigate was calculated,and the incidence of various non-infectious diseases at different stages was compared accordingly.Results For non-infectious diseases occurred during the whole course of the mission,the top 3 non-infectious diseases were lumbarmuscle strain,insomnia and motion sickness.Then came dermatitis,dental ulcer,xerophthalmia,trauma and cardiovascular diseases.The onset stages (early,middle and late stages)of various non-infectious diseases were different from one another.The incidence oflumbar muscle strain,insomnia,dermatitis,dental ulcer and xerophthalmia at late stage of the mission was significantly higher than thatat the early stage(P <0.01),and the incidence of motion sickness at the early stage was significantly higher than that at late stage(P <0.01).Conclusion With the extension of the escort mission,the incidence of lumbar muscle strain,insomnia,dermatitis,dentalulcer and xerophthalmia increased,while the incidence of motion sickness decreased.

Objective To observe the relationship between sleep quality and types of behavior in navy shipboard personnel,so as to provide evidences for medical support.Methods A total of 789 subjects were randomly selected from navy shipboard personnel and 771 personnel were selected as researched subjects at last.Questionnaires of behavior types and Pittsburgh Sleep Quality Index (PSQI) were carried out in the selected subjects.Fifteen sailors were randomly selected in accordance with types of behavior and polysomnogram was analyzed with polysomnography index (PSGI).Results Of all the subjects,197 were of the type A behavior (accounting for 25.72％),386 were of the type M behavior (50.39％) and 188 were of the type B behavior(23.89％).There were no statistical differences in hypnotic scores,when type A was compared with type M and type B (P ＞ 0.05).Other scores in the subjects of the type A were all higher than those of the type B subjects(P ＜ 0.05,P ＜ 0.01).As for the type M subjects,the scores of sleep efficiency,sleep disorder,day-time dysfunction and total scores were higher than those of the type B subjects(P ＜0.05,P ＜0.01).Sleep latency in phase 1 and phase 2 were higher for the type A group and were all higher than those of the type M and B groups (P ＜ 0.05,P ＜ 0.01).Slow-wave-sleep (SWS),rapid-eye-movement (REM) and REM latency for the subjects of the type A group were all lower than those of the type M and B groups(P ＜0.05,P ＜0.01).The proportion of phase 1,sleep latency and REM for the type M group were all higher than those of the type B group(P ＜ 0.05),while REM latency was lower than that of the type B group (P ＜ 0.05).The number of slight awakening and total awakening time were higher for type A group than those of the type M and type B groups P ＜ 0.05,P ＜ 0.01).Total sleep time in the type A group was lower than those of the type M and type B groups (P ＜ 0.05).Sleep maintenance time (SMT) in the type A group was also lower than those of the type M and type B groups (P ＜ 0.05).Sleep maintenance time (SMT) was lower in type A group than type B group (P ＜ 0.05).There was no statistical differences in SMT between type A group and type M group (P ＞ 0.05).Sleep efficiency in type A group was lower than those of the type M and type B groups (P ＜0.05,P ＜0.01).The number of slight awakenings for the type M group was more than that of the type B group(P ＜ 0.01) and sleep maintenance time was lower than that of the type B group(P ＜ 0.01).Conclusions Sleep quality was related with types of behavior for navy shipboard personnel.There were more sleep disorders in those with type A behavior.