As an airway management tool,the seal performance of the laryngeal mask is crucial.The seal pressure of the laryngeal mask is a key indicator for evaluating the performance of the laryngeal mask.Appropriate seal pres-sure is of great clinical significance to ensure effective ventilation and avoid complications.This article reviews the factors that affect the seal pressure of the laryngeal mask,including structural design,material characteristics,in-flation volume,insertion skill,airway pressure,and patients'individual characteristics.Understanding and optimi-zing the above factors can help anesthesiologists to better apply the laryngeal mask in clinical anesthesia,to reduce patient complications,and improve patient safety as well as comfort.