Objective:To explore the multiple mediating roles of intrinsic motivation and proactive behavior in the influence mechanism of perceived overqualification on the information literacy of Operating Room nurses engaged in organ transplantation.Methods:On November 2023, 308 Operating Room nurses engaged in organ transplantation from 12 hospitals in China were selected for the survey using convenience sampling method. General information questionnaire, Information Literacy Self-Rating Scale for Clinical Nurses, the 9-item Scale of Perceived Over Qualification, Intrinsic Motivation Scale, and Proactive Behavior Scale were used to investigate and to construct the chain mediating model.Results:A total of 308 questionnaires were collected and 294 questionnaires were valid, with a valid recovery rate of 95.45%. The total scores of information literacy, perceived overqualification, intrinsic motivation and proactive behavior of 294 Operating Room nurses engaged in organ transplantation were (133.95±19.07), (23.71±7.82), (76.47±13.38) and (38.01±6.31) respectively. The indirect effect of perceived overqualification of Operating Room nurses engaged in organ transplantation on information literacy existed, with a total indirect effect value of -0.348. The specific indirect effect of intrinsic motivation was 40.80% of the total indirect effect, the specific indirect effect of proactive behavior was 31.03% of the total indirect effect, and the chain mediating effect of intrinsic motivation and proactive behavior was 28.16% of the total indirect effect.Conclusions:Multiple mediating roles of intrinsic motivation and proactive behavior in the influence mechanisms of perceived overqualification on the information literacy of Operating Room nurses involved in organ transplantation are established. Managers can improve the information literacy of Operating Room nurses engaged in organ transplantation by reducing their perceived overqualification and stimulating intrinsic motivation and proactive behavior.

Objective:To explore the multiple mediating roles of intrinsic motivation and proactive behavior in the influence mechanism of perceived overqualification on the information literacy of Operating Room nurses engaged in organ transplantation.Methods:On November 2023, 308 Operating Room nurses engaged in organ transplantation from 12 hospitals in China were selected for the survey using convenience sampling method. General information questionnaire, Information Literacy Self-Rating Scale for Clinical Nurses, the 9-item Scale of Perceived Over Qualification, Intrinsic Motivation Scale, and Proactive Behavior Scale were used to investigate and to construct the chain mediating model.Results:A total of 308 questionnaires were collected and 294 questionnaires were valid, with a valid recovery rate of 95.45%. The total scores of information literacy, perceived overqualification, intrinsic motivation and proactive behavior of 294 Operating Room nurses engaged in organ transplantation were (133.95±19.07), (23.71±7.82), (76.47±13.38) and (38.01±6.31) respectively. The indirect effect of perceived overqualification of Operating Room nurses engaged in organ transplantation on information literacy existed, with a total indirect effect value of -0.348. The specific indirect effect of intrinsic motivation was 40.80% of the total indirect effect, the specific indirect effect of proactive behavior was 31.03% of the total indirect effect, and the chain mediating effect of intrinsic motivation and proactive behavior was 28.16% of the total indirect effect.Conclusions:Multiple mediating roles of intrinsic motivation and proactive behavior in the influence mechanisms of perceived overqualification on the information literacy of Operating Room nurses involved in organ transplantation are established. Managers can improve the information literacy of Operating Room nurses engaged in organ transplantation by reducing their perceived overqualification and stimulating intrinsic motivation and proactive behavior.

Objective:To construct a competency evaluation indicator system for infection prevention and control nurses in Operating Rooms (hereinafter referred to as "IPC") and provide an objective basis for the management of IPC nurses.Methods:From June to November 2022, an initial competency evaluation indicator system for IPC nurses was developed through literature review and semi-structured interviews. The Delphi method was employed to consult 20 experts from 11 provinces and municipalities across the country. Analytical Hierarchy Process (AHP) and mean distribution method were applied to quantify and determine the weight of each level of indicators within the system.Results:Nineteen experts were finally included, with two rounds of questionnaire recovery rates of 95.00% (19/20) and 100.00% (19/19), respectively. The authority coefficients of the experts were 0.858 and 0.861, familiarity coefficients were 0.850 and 0.853, and coefficients of judgment basis were 0.865 and 0.868, respectively. The Kendall's W coefficient of concordance for the two rounds of inquiries were 0.139 and 0.202 ( P<0.05), respectively. The final IPC nurse competency evaluation indicator system included six primary indicators, 22 secondary indicators, and 66 tertiary indicators. Conclusions:The constructed IPC nurse competency evaluation indicator system is scientific, reasonable, objective, and comprehensive, providing a valuable reference for the capability training, assessment, entry standards, and qualification certification of IPC nurses.

Objective:To investigate the clinical characteristics of abdominal infection related secondary hemorrhage and partition of intra-abdominal infection after pancreaticoduodenectomy (PD).Methods:The retrospective and descriptive study was conducted. The clinical data of 25 patients with abdominal infection related secondary hemorrhage after PD who were admitted to The First Affiliated Hospital of Xi ′an Jiaotong University from January 2009 to December 2017 were collected. There were 18 males and 7 females, aged (63±11)years. Measurement data with normal distribution were represented as Mean± SD, and measurement data with skewed distribution were represented as M( Q1, Q3). Count data were described as absolute numbers. Results:(1) Clinical charac-teristics of abdominal infection related secondary hemorrhage after PD. Of 25 patients, there were 21 cases diagnosed with pancreatic fistula, 2 cases with negative for amylase test in abdominal drainage fluid, and 2 cases with unknown conditions of pancreatic fistula. There were 16 cases with sentinel hemorrhage and 9 cases without sentinel hemorrhage. Of 25 patients, 10 cases were evaluated as grade A bleeding, 10 cases were evaluated as grade B bleeding, and 5 cases were evaluated as grade C bleeding. The types of pathogenic microorganisms cultured in the peritoneal drainage fluid of 25 patients included 7 cases of simple Gram positive (G +) bacteria, 6 cases of simple Gram negative (G -) bacteria, 8 cases of both G + bacteria and G - bacteria, 1 case of G + bacteria and fungi, and 3 cases of G + bacteria, G - bacteria and fungi. There were 3 cases cultured with carbapenem-resistant Acinetobacter baumannii. There were 17 patients with fluid accumulation in the D region confirmed by abdominal computered tomography, including 2 cases of simple fluid accumulation in the D region and 15 cases of fluid accumulation in the D region and other regions. Of 25 patients, 12 cases underwent simple conservative medical treatment, 8 cases underwent digital subtraction angiography (DSA) hemostasis, 2 cases underwent DSA combined with surgical hemostasis, 1 case underwent endoscopic hemostasis, 1 case underwent surgical hemostasis, and 1 case underwent endoscopic + DSA hemostasis. Of 25 patients, 5 patients died. (2) Treatment methods and clinical outcomes of patients with abdo-minal infection in different regions of the partition of intra-abdominal infection. Of the 17 patients with clear regions of the partition of intra-abdominal infection, there were 6 cases with D region combined with ≤ 1 other region of the partition of intra-abdominal infection who did not receive surgical treatment survived, there were 11 cases with D region combined with ≥2 other regions of the partition of intra-abdominal infection who mainly received DSA or combined treatment, including 8 cases survived and 3 cases dead. Conclusions:The abdominal infection related secondary hemorrhage after pancreaticoduodenectomy is mainly due to D region of the partition of intra-abdominal infection, and the pathogen mainly presents as mixed infection and multi-drug-resistant bacterial infection. When the spread of infected lesions leads to D region combined with ≥2 other regions of the partition of intra-abdominal infection, the intervention measures are significantly upgraded, and the risk of patient death increases.

Objective:To investigate the clinical characteristics of abdominal infection related secondary hemorrhage and partition of intra-abdominal infection after pancreaticoduodenectomy (PD).Methods:The retrospective and descriptive study was conducted. The clinical data of 25 patients with abdominal infection related secondary hemorrhage after PD who were admitted to The First Affiliated Hospital of Xi ′an Jiaotong University from January 2009 to December 2017 were collected. There were 18 males and 7 females, aged (63±11)years. Measurement data with normal distribution were represented as Mean± SD, and measurement data with skewed distribution were represented as M( Q1, Q3). Count data were described as absolute numbers. Results:(1) Clinical charac-teristics of abdominal infection related secondary hemorrhage after PD. Of 25 patients, there were 21 cases diagnosed with pancreatic fistula, 2 cases with negative for amylase test in abdominal drainage fluid, and 2 cases with unknown conditions of pancreatic fistula. There were 16 cases with sentinel hemorrhage and 9 cases without sentinel hemorrhage. Of 25 patients, 10 cases were evaluated as grade A bleeding, 10 cases were evaluated as grade B bleeding, and 5 cases were evaluated as grade C bleeding. The types of pathogenic microorganisms cultured in the peritoneal drainage fluid of 25 patients included 7 cases of simple Gram positive (G +) bacteria, 6 cases of simple Gram negative (G -) bacteria, 8 cases of both G + bacteria and G - bacteria, 1 case of G + bacteria and fungi, and 3 cases of G + bacteria, G - bacteria and fungi. There were 3 cases cultured with carbapenem-resistant Acinetobacter baumannii. There were 17 patients with fluid accumulation in the D region confirmed by abdominal computered tomography, including 2 cases of simple fluid accumulation in the D region and 15 cases of fluid accumulation in the D region and other regions. Of 25 patients, 12 cases underwent simple conservative medical treatment, 8 cases underwent digital subtraction angiography (DSA) hemostasis, 2 cases underwent DSA combined with surgical hemostasis, 1 case underwent endoscopic hemostasis, 1 case underwent surgical hemostasis, and 1 case underwent endoscopic + DSA hemostasis. Of 25 patients, 5 patients died. (2) Treatment methods and clinical outcomes of patients with abdo-minal infection in different regions of the partition of intra-abdominal infection. Of the 17 patients with clear regions of the partition of intra-abdominal infection, there were 6 cases with D region combined with ≤ 1 other region of the partition of intra-abdominal infection who did not receive surgical treatment survived, there were 11 cases with D region combined with ≥2 other regions of the partition of intra-abdominal infection who mainly received DSA or combined treatment, including 8 cases survived and 3 cases dead. Conclusions:The abdominal infection related secondary hemorrhage after pancreaticoduodenectomy is mainly due to D region of the partition of intra-abdominal infection, and the pathogen mainly presents as mixed infection and multi-drug-resistant bacterial infection. When the spread of infected lesions leads to D region combined with ≥2 other regions of the partition of intra-abdominal infection, the intervention measures are significantly upgraded, and the risk of patient death increases.

Objective:To construct a nomogram model for nasopharyngeal bleeding risk in nasopharyngeal carcinoma patients underwent radiotherapy, and to verify the application value of the model.Methods:From June 2020 to December 2021, 317 nasopharyngeal carcinoma patients underwent radiotherapy in the First Affiliated Hospital of Zhengzhou University were enrolled by the convenience sampling method, and divided into the bleeding group and the non-bleeding group according to the occurrence of nasopharyngeal hemorrhage bleeding. Univariate analysis and Logistic regression analysis were used to analyze the independent risk factors of nasopharyngeal hemorrhage patients underwent radiotherapy, and a nomogram model was constructed. Correction curve, Hosmer- Lemeshow ( H- L) goodness fit test and receiver operating characteristic (ROC) curve were used to evaluate the predictive efficiency of the model, and the area under ROC curve was calculated. Results:Multivariate Logistic regression analysis results showed that hypertension, skull base invasion, synchronous chemotherapy, anterior field+skull base irradiation, tumor rectum growth and average radiation dose≥70 Gy were the independent risk factors of nasopharyngeal hemorrhage in nasopharyngeal carcinoma patients underwent radiotherapy ( P<0.05). H- L goodness fit test results showed that there was no significant difference between the calibration curve predicted by the nomogram model and the ideal model curve (χ 2=3.469, P=0.614), and the area under ROC curve was 0.778 (95% CI: 0.705-0.947) . Conclusions:Hypertension, skull base invasion, synchronous chemotherapy, anterior field+skull base irradiation, tumor crypt growth and radiation dose≥70 Gy were the independent risk factors for nasopharyngeal hemorrhage in nasopharyngeal cancer patients underwent radiotherapy. The nomogram model constructed in this study has good differentiation and accuracy, which can provide a reference for medical staffs to develop targeted intervention strategies.

OBJECTIVE:To study the effect of peiminine on increasing the chemosensitivity of 5 kinds of cancer cells. METH-ODS:Using human esophageal cancer Eca-109 cell,human breast cancer MCF-7 cell,human small cell lung cancer A549 cell,hu-man hepatoma HepG2 cell and human cervical cancer HeLa cell as objects,MTT colorimetric method was used to detect the growth inhibition rate of above-mentioned 5 kinds of cancer cells after treated by peiminine with maximal non-toxic mass concentra-tion(20 μg/mL)and adriamycin with different gradient mass concentrations(0.026-2.1,0.026-2.1,0.125-2.0,0.125-2.0,0.0625-0.10μg/mL)for 72 h. The half inhibitory concentration(IC50)was calculated. Crystal violet staining method was adopted to observe the proliferation of above-mentioned cancer cells after treated by peiminine with maximal non-toxic mass concentration and adriamycin with low mass concentrations(0.02,0.005,0.04,0.02,0.01 μg/mL)for 7 d. Solvent control,single use of peiminine and adriam-ycin control were conducted. RESULTS:Compared with single use of adriamycin,the combination use of peiminine and adriamy-cin can improve the growth inhibition rate of 5 kinds of cancer cells to certain degree,most of the differences were statistically sig-nificant (P<0.05 or P<0.01);and IC50 was obviously decreased,with statistical significances (P<0.05 or P<0.01). Compared with solvent control,single use of peiminine or adriamycin had no obvious effects on the proliferation of above-mentioned cancer cells in 7 d,and the combination use of peiminine and adriamycin can obviously inhibit the proliferation of above-mentioned cancer cells in 7 d. CONCLUSIONS:Peiminine can enhance the sensitivity of above-mentioned-mentioned 5 kinds of cancer cells to cer-tain degree,showing certain chemosensitivity increasing effect.

Objective To evaluate the clinical result of Hering's law in the correction of asymmetric bilateral ptosis.Methods From January 2014 to July 2016,165 cases divided into 2 groups with asymmetric bilateral ptosis in mild and moderate ptosis were corrected with aponeurosis advancement type correction:A group of 15 cases,in which the surgery does not consider the influence of Hering's law,the first correction of mild side,and then corrected the heavier side;B group of 150 cases,in which the Hering's law was applied,the first correction of severe side so that the margin reached the edge of the cornea is tangent or low 0.5-1.0 mm,and then corrected mild side.That the difference of symmetry between the two sides of the palpebral fissure was less than 0.5 mm,and the follow-up was more than 3 months.The Pearson chi square test was used to compare the differences between the two groups.Results In this group,165 cases were followed up for 3-24 months,10 cases (66.67％) was satisfactory in group A (15 cases);145 cases (96.67％) was satisfactory in group B (150 cases);After 3 months,all the failure cases got satisfactory result by using the Hering's law in corrective surgery again.The P value of chi square test between groups was less than 0.05.Conclusions The application of Hering's law in the correction of asymmetry bilateral ptosis is more satisfactory.

OBJECTIVETo propose a clinically practical and simple fiber tracking method for language pathways, and to explore its feasibility in preoperative planning for brain tumors adjacent to the language cortex.

METHODSDiffusion tensor imaging was examined in 18 healthy subjects and 13 patients with brain tumors adjacent to the language cortex between December 2013 and June 2014. The associated fibers of language pathways were reconstructed using a commercial software (Syngo workstation). Firstly, the feasibility of fiber tracking method for language pathways in healthy subjects were studied, and then its application was assessed in patients with brain tumors. The anatomic relationship between tumors and the associated fibers was analyzed.

RESULTSBy selecting appropriate regions of interest, the associated fibers in the dorsal pathways (superior longitudinal fasciculus/arcuate fasciculus, including both direct and indirect pathways) and ventral pathways (uncinate fasciculus, middle longitudinal fasciculus, inferior longitudinal fasciculus and inferiorfronto-occipital fasciculus) were reconstructed in all 18 healthy subjects. In patients with brain tumors, the relationship between the tumors and adjacent associated fibers were divided into two types: adjacent associated fibers could be displaced or separated, and involved the superior longitudinal fasciculus/arcuate fasciculus (n=6), middle longitudinal fasciculus (n=4), uncinate fasciculus (n=3), inferior longitudinal fasciculus (n=3) and inferiorfronto-occipital fasciculus (n=2); alternatively, the adjacent associated fibers were infiltrated or destroyed, and involved the inferiorfronto-occipital fasciculus (n=10), uncinate fasciculus (n=8), middle longitudinal fasciculus (n=5), inferior longitudinal fasciculus (n=4) and superior longitudinal fasciculus/arcuate fasciculus (n=3).

CONCLUSIONSThe associated fibers of language pathways could be visualized rapidly and in real-time by fiber tracking technology based on diffusion tensor imaging. This is feasible for preoperative planning regarding brain tumors adjacent to the language cortex.

Brain Neoplasms ; surgery ; Cerebral Cortex ; surgery ; Diffusion Tensor Imaging ; Humans ; Language ; Neural Pathways ; Postoperative Complications ; prevention & control