1.Characteristics of body height, body weight and body mass index distributions in children aged 3-17 years in China
Wei CAO ; Peipei XU ; Titi YANG ; Xuehong PANG ; Zhenyu YANG ; Yuying WANG ; Tao XU ; Bowen CHEN ; Wenhua ZHAO ; Qian ZHANG ; Yuna HE
Chinese Journal of Epidemiology 2024;45(11):1487-1493
Objective:To investigate the distribution characteristics of body height, body weight and body mass index (BMI) in children aged 3-17 years in China.Methods:Data were obtained from the National Nutrition and Health Systematic Survey in 0-18 years old children in China. The study selected 70 853 children aged 3-17 years from 28 urban and rural survey sites in 14 provinces (autonomous regions and municipalities) in 7 regions of China with multi-stage stratified cluster random sampling. M ( Q1, Q3) was used to describe the region, age and gender specific body height, body weight and BMI in the children aged 3-17 years. Wilcoxon rank sum test was used to compare the body height, body weight, and BMI between boys and girls in same age group. Kruskal-Wallis H rank sum test was used to compare the body height, body weight and BMI among boys in different age groups and among girls in different age groups, as well as among boys in same age group and among girls in same age group from different regions, and DSCF method was used for further pairwise comparisons. Results:In this study, the median body height and body weight were 172.0 cm and 62.9 kg in 17-year-old boys and 160.0 cm and 53.7 kg in 17-year-old girls. The median for children's body height, body weight, and BMI in most age groups were higher in northeastern and northern China than in southern China, and the differences could be observed until age 17 years. The differences in body weight and BMI in children in northeastern and northern China were greater in Q3 than in Q1 compared with southern China. Conclusions:The body height of children aged 3-17 years continues to increase in China. Northeastern and northern China have more children with higher bodyweight, showing an obvious body weight increase trend, to which close attention needs to be paid.
2.The effective connection of default mode network changes in patients with type 2 diabetes mellitus
Liying ZHANG ; Zhizhong SUN ; Limin GE ; Zidong CAO ; Weiye LU ; Wenbin QIU ; Yuna CHEN ; Shijun QIU
Chinese Journal of Diabetes 2024;32(2):91-96
Objective To investigate the influence of type 2 diabetes mellitus(T2DM)on cognitive function and the effective connectivity with in the default mode network(DMN)in the brain.Methods A total of 93 hospitalized patients diagnosed with T2DM were enrolled in this study as T2DM group from The First Affiliated Hospital of Guangzhou University of Chinese Medicine during September 2021 to December 2022.Simultaneously,108 healthy individuals were recruited from the community as normal control(NC)group.The cognitive functions were evaluated in the two groups.A random dynamic causal modeling approach was employed to analyze the effective connectivity within DMN in both groups.Additionally,Pearson correlation analysis was performed to examine the association between differential connectivity,clinical indicators,and cognitive scores in both groups.Results In comparison to the NC group,T2DM individuals exhibited statistically significant reductions in scores in the auditory verbal learning test(AVLT)for immediate recall and the digit symbol substitution test(DSST)(P<0.05).Additionally,they displayed a notable decrease in effective connectivity from the left lateral parietal cortex(LLPC)to the posterior cingulate cortex(PCC),as well as from the LLPC to the right lateral parietal cortex(RLPC)within the DMN(P<0.05).Pearson correlation analysis unveiled a negative association between HbA1c levels and the strength of effective connectivity from LLPC to PCC.Conversely,a positive correlation was observed between AVLT(immediate)scores and the strength of effective connectivity from LLPC to PCC and LLPC to RLPC.Additionally,DSST scores displayed a positive correlation with the strength of effective connectivity from LLPC to PCC(P<0.05).Conclusion Patients with T2DM display compromised effective connectivity from LLPC to PCC and LLPC to RLPC within the DMN network,and this alteration may associated with cognitive impairment.
3.Analysis of the efficacy of fiber laser stapes fenestration in the treatment of 58 cases of otosclerosis and ossicular malformation
Yuna ZHANG ; Shijie QIU ; Bing CAO ; Zhengyu WEI ; Zhisen SHEN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2024;59(8):797-802
Objective:To explore the surgical efficacy of conductive deafness caused by otosclerosis and ossicular malformation with 980 nm fiber laser stapedial floor fenestration.Methods:Data of 58 patients (ears) who were diagnosed with conductive deafness caused by otosclerosis (49 ears) and ossicular malformation (9 ears) treated by 980 nm Diode laser small-fenestra stapedotomy were retrospectively analyzed. Air conduction (AC) thresholds, bone conduction (BC) thresholds, and air-bone gap (ABG) at 0.5, 1, 2, 4 kHz pure tone frequencies were compared before and 3 months after surgery, and the advantages and precautions of 980 nm fiber laser were summarized. Paired t-test (SPSS 26.0 software) was use to analyze the listening data. Results:Fiber optic laser stapes fenestration and artificial stapes implantation were successfully completed in all 57 cases (ears), the hearing of another one patient (ear) with floating malformation of detachment of stapedial floor was lower than that before surgery. Preoperative at 0.5, 1, 2, 4 kHz frequencies of AC thresholds, BC thresholds, and ABG were (65.4±9.7) dB, (27.2±8.9) dB, and (38.2±9.8) dB respectively. Postoperative 3 months at the same frequency of AC thresholds, BC thresholds, and ABG were (42.1±11.3) dB, (26.9±6.6) dB, and (15.2±9.1) dB. Preoperative and postoperative of AC threshold and ABG were statistically significant at 0.5, 1, 2, 4 kHz ( t value was 13.270 and13.948, both P<0.01), and yet the BC threshold was not statistically significant before and after surgery at the same frequency ( t=0.418, P>0.05). Conclusions:980 nm fiber laser stapes floor fenestration is an effective treatment for conductive deafness caused by otosclerosis and ossicular malformation.
4.Protective Effect of Flos Puerariae,Hoveniae Semen, and Their Compatibility on Acute Alcoholic Gastric Mucosal Injury in Mice and Mechanism
Wenyong LIAO ; Muyun LI ; Xiao DONG ; Can CAO ; Min HUO ; Yuna REN ; Haiyan LIU ; Linlin XIU ; Cheng HE ; Angran FAN ; Shaohong CHEN ; Gansheng ZHONG
Chinese Journal of Experimental Traditional Medical Formulae 2023;29(10):39-47
ObjectiveTo explore the improvement effect of Flos Puerariae, Hoveniae Semen, and their compatibility on acute alcoholic gastric mucosal injury, and lay a foundation for further development of Flos Puerariae, Hoveniae Semen, and their compatibility in the prevention and treatment of alcohol-induced multiple organ injury. MethodThe acute alcohol-induced gastric mucosal injury model of mice was established by multiple intragastric administration of 56% Hongxing Erguotou liquor (15 mL·kg-1). A total of 120 male ICR mice were randomly divided into 8 groups, namely, the blank group, model group, omeprazole group (0.026 g·kg-1), Flos Puerariae-Hoveniae Semen (compatibility) high, medium, and low-dose groups (29.2,14.6, 7.3 g·kg-1), Flos Puerariae group (19.5 g·kg-1), and Hoveniae Semen group (19.5 g·kg-1), with 15 mice in each group. After one week of adaptive feeding, the animals were pre-administrated with the corresponding drug at the rate of 10 mL·kg-1 for 3 d. From the 4th day, after 1 h of administration, Erguotou liquid was administrated at the rate of 15 mL·kg-1 and the blank group was administrated with the same volume of deionized water to record the drunkenness and sober up time. The administration was lasted for 3 d. One hour after the last administration, the eyeballs were removed and the mice were sacrificed. The concentration of ethanol in serum was determined by gas chromatograph, and the activity of ethanol dehydrogenase (ADH) in gastric mucosa was determined by ultraviolet-vis spectrophotometer. Hematoxylin-eosin (HE) staining was used to observe the pathological changes in gastric mucosa. Serum inflammatory factors were determined by enzyme-linked immunosorbent assay (ELISA). The mRNA expression of nuclear transcription factor-κB (NF-κB) p65 and NF-κB inhibitory protein α (IκBα) were detected by real-time polymerase chain reaction (Real-time PCR). ResultAs compared with the normal group, the content of interleukin-6 (IL-6), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) in serum of mice in the model group was increased (P<0.05), the mRNA expression of NF-κB p65 in gastric mucosa tissues was increased (P<0.01), and the mRNA expression of IκBα was decreased (P<0.01). As compared with the model group, the drunkenness time of the omeprazole group, high and medium-dose compatibility groups, and Flos Puerariae group was prolonged (P<0.05), the sober up time of the high and medium-dose compatibility groups was shortened (P<0.05), the ethanol concentration in the serum of the high-dose compatibility group was decreased (P<0.05), the ADH activity in the gastric mucosa of the omeprazole group and high and medium-dose compatibility groups was increased (P<0.05), the macroscopic injury score of the high, medium, and low-dose compatibility groups and Flos Puerariae group was decreased (P<0.05), the score of pathological injury in the omeprazole group, high, medium, and low-dose compatibility groups, and Flos Puerariae group was decreased (P<0.01), the expression of IL-6 in serum of all drug groups was decreased (P<0.05), the expression of IL-1β in serum of the omeprazole group, high, medium, and low-dose Flos Puerariae groups, and Hoveniae Semen group was decreased (P<0.05), the expression of TNF-α in serum of high and medium-dose groups was decreased (P<0.05), the mRNA expression of NF-κB p65 in gastric mucosa tissues of all drug groups was decreased (P<0.05), and the mRNA expression of IκBα in gastric mucosa tissues of the omeprazole group and high, medium, and low-dose compatibility groups was increased (P<0.05). As compared with the high-dose compatibility group, the drunkenness time in the low-dose compatibility group and Hoveniae Semen group was shortened (P<0.01), the sober up time in the Flos Puerariae and Hoveniae Semen groups was prolonged (P<0.01), the concentration of ethanol in the serum of the medium and low-dose compatibility groups, Flos Puerariae group, and Hoveniae Semen group increased (P<0.05), the macroscopic injury score of the medium and low-dose compatibility groups and Hoveniae Semen group was increased (P<0.05), the pathological injury score of the medium and low-dose compatibility groups, Flos Puerariae group, and Hoveniae Semen group was increased (P<0.01), the content of IL-1β in serum of low-dose compatibility group, Flos Puerariae group, and Hoveniae Semen group was increased (P<0.01), and the mRNA expression of IκBα in gastric mucosa of the Flos Puerariae group and Hoveniae Semen group was decreased (P<0.05). As compared with the medium-dose compatibility group, the drunkenness time in the Hoveniae Semen group was shortened (P<0.05), the sober up time in the Flos Puerariae group was prolonged (P<0.05), the pathological injury score in the Flos Puerariae group and Hoveniae Semen group was increased (P<0.01), and the content of IL-1β in serum of the low-dose compatibility group, the Flos Puerariae group, and Hoveniae Semen group was increased (P<0.05). As compared with the low-dose compatibility group, the pathological injury score of the Hoveniae Semen group was increased (P<0.05). ConclusionFlos Puerariae, Hoveniae Semen, and their compatibility play a role in preventing and treating acute alcoholic gastric mucosal injury in mice, which may be related to the inhibition of the expression of NF-κB signal pathway in gastric mucosa, and the high-dose compatibility group has the optimal effect.
5.Mediating effect of patient motivation between health literacy and self-management behaviour in patients with knee osteoarthritis
Yuna CAI ; Xixi HUANG ; Jie YAO ; Jingjing CAO ; Yuanyuan FANG ; Xia SHAO ; Xiaowei LI ; Yan GUO
Modern Clinical Nursing 2023;22(10):16-23
Objective To investigate the status quo of health literacy,motivation and self-management behaviours of patients with knee osteoarthritis(KOA),to explore the influence of health literacy and motivation on self-management behaviours to the patients with KOA,and to clarify the relationships among the three factors.Methods Convenience sampling method was used to select 169 KOA patients who were treated in 3 tertiary hospitals in Xianyang between September and December 2021.General status table,chronic disease health literacy scale,patient motivation scale and chronic disease self-management behaviour scale were employed in the on-the-spot survey.Pearson correlation was used to analyze the correlation of health literacy,motivation and self-management behaviour of patients with KOA.Results Total scores of health literacy,motivation and self-management behaviour of the patients with KOA were 79.66±11.91,54.97±9.95 and 23.75±8.89,respectively.It was found that health literacy and motivation of the patients were positively correlated with their self-management behaviour(r=0.872,r=0.822,both P<0.01).Health literacy of the patients was positively correlated with motivation of patients(r=0.877,P<0.01).Health literacy of the patients could be used to directly predict self-management behaviour of patients(β=0.708,95%CI:0.539-0.876),as well as to predict self-management behaviour of the patients through the mediating effect of patient motivation(β=0.228,95%CI:0.676-0.787).The mediating effect accounted for 24.36%of the total effect.Conclusions The health literacy,motivation and self-management behaviours of patients with KOA are all poor and they should be further improved.Patient motivation is the mediating variable in health literacy and self-management behaviour of the patients.It is suggested that nursing staff could encourage the motivation of patients hence to improve the self-management behaviour in the patients with KOA based on an improvement of health literacy.
6.Psychological health of nurses in operating room participating in organ donation and intervention effect
Yuna PENG ; Chunying LIU ; Hua ZHANG ; Na ZHANG ; Yi CAO ; Yanyan WU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2020;38(4):271-274
Objective:To understand the effect of organ donation surgery on the mental health of nurses in operating room, and to explore the intervention effects.Methods:From Jan.2015 to Dec. 2018, 60 operating room nurses in our hospital participating in organ donation surgery were selected for investigation of mental health, and were intervened by group psychological training, positive psychological intervention, improving shift arrangement system and financial support. The SCL-90 scale and DAP-R scale were used to evaluate before and after intervention.Results:The mean scores of somatization, interpersonal sensitivity, depression, anxiety, terror, paranoia and psychoticism in SCL-90 scale of 60 operating room nurses were (2.07±0.63) , (2.07±0.69) , (1.88±0.62) , (1.71±0.57) , (1.78±0.67) , (1.71±0.68) , (1.73±0.60) before intervention respectively, which were significantly higher than the Chinese norm ( P<0.01) and those[ (1.64±0.60) , (1.46±0.57) , (1.53±0.62) , (1.48±0.60) , (1.28±0.50) , (1.45±0.56) , (1.43±0.52) ] after intervention were lower than before ( P<0.01) . Before and after the intervention, the scores of DAP-R scale tended to be death fear dimension and acceptance dimension, the proportion of the death fear dimension was 16.7% (10/60) and 6.7% (4/60) , respectively, and the approaching acceptance dimension was 83.3% (50/60) and 93.3% (56/60) . The proportion of the nurses with scores of SCL-90 scale ≥160 after the intervention was significantly lower than that before the intervention (χ 2=5.82, P<0.05) . Conclusion:The mental health of nurses in the operating room participating in organ donation surgery is lower; After intervention, the investigated nurses present improved mental health and positively emotional attitude towards death.
7.Psychological health of nurses in operating room participating in organ donation and intervention effect
Yuna PENG ; Chunying LIU ; Hua ZHANG ; Na ZHANG ; Yi CAO ; Yanyan WU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2020;38(4):271-274
Objective:To understand the effect of organ donation surgery on the mental health of nurses in operating room, and to explore the intervention effects.Methods:From Jan.2015 to Dec. 2018, 60 operating room nurses in our hospital participating in organ donation surgery were selected for investigation of mental health, and were intervened by group psychological training, positive psychological intervention, improving shift arrangement system and financial support. The SCL-90 scale and DAP-R scale were used to evaluate before and after intervention.Results:The mean scores of somatization, interpersonal sensitivity, depression, anxiety, terror, paranoia and psychoticism in SCL-90 scale of 60 operating room nurses were (2.07±0.63) , (2.07±0.69) , (1.88±0.62) , (1.71±0.57) , (1.78±0.67) , (1.71±0.68) , (1.73±0.60) before intervention respectively, which were significantly higher than the Chinese norm ( P<0.01) and those[ (1.64±0.60) , (1.46±0.57) , (1.53±0.62) , (1.48±0.60) , (1.28±0.50) , (1.45±0.56) , (1.43±0.52) ] after intervention were lower than before ( P<0.01) . Before and after the intervention, the scores of DAP-R scale tended to be death fear dimension and acceptance dimension, the proportion of the death fear dimension was 16.7% (10/60) and 6.7% (4/60) , respectively, and the approaching acceptance dimension was 83.3% (50/60) and 93.3% (56/60) . The proportion of the nurses with scores of SCL-90 scale ≥160 after the intervention was significantly lower than that before the intervention (χ 2=5.82, P<0.05) . Conclusion:The mental health of nurses in the operating room participating in organ donation surgery is lower; After intervention, the investigated nurses present improved mental health and positively emotional attitude towards death.
8.The association between eating out of home and overweight/obesity among Chinese adults.
Keke CAO ; Yuna HE ; Xiaoguang YANG
Chinese Journal of Preventive Medicine 2014;48(12):1088-1092
OBJECTIVETo investigate the association between out-of-home eating (OH eating) and overweight/obesity among adults in China.
METHODSA total of 33 828 subjects aged 18-60 years old from the 2002 China National Nutrition and Health Survey were selected to calculate their daily consumption of food and nutrition, when people eating at home or out-of-home. The 24-hour dietary recall method for 3 consecutive days was used to collect food intake information ( not including the condiment intake). The logistic regression method was used to analyze the relationship between OH eating and overweight/obesity.
RESULTSThe prevalence of OH eating among Chinese adults aged 18-60 years old was 28.3% (9 562/33 828) in 2002. Overall, the prevalence of OH eating was significantly greater among men compared to women (P < 0.05) , and the rate for men was 32.4% (5 117/15 805), and the rate for women was 24.7% (4 445/18 023). Besides, men who ate out of home showed a higher prevalence of overweight and obesity than those who ate at home (P < 0.05) , and the prevalence of overweight and obesity among them were 38.9% (1 991/5 117) and 31.7% (3 389/10 684), respectively. While women who ate at home showed a higher prevalence of overweight and obesity than those who ate out of home, and the prevalence of overweight and obesity among them were 38.1% (5 174/13 571) and 35.6% (1 581/4 445), respectively. Compared with at-home eating group, 130.4 kJ energy, 12.2 g fat, 6.2 g protein and 67.1 mg sodium were excessively consumed per day for men, and 102.5 kJ energy, 8.6 g fat, 3.4 g protein and 60.6 mg sodium were excessively consumed per day for women. To sum up, OH eating was positively associated with overweight and obesity among men (OR = 1.18, 95% CI:1.09-1.27) , but not among women (OR = 0.94, 95% CI:0.87-1.01).
CONCLUSIONOH eating was positively associated with overweight and obesity among men in China.
Adult ; China ; Diet ; Eating ; Female ; Health Surveys ; Humans ; Male ; Obesity ; Overweight ; Prevalence ; Restaurants ; Sex Factors ; Sodium, Dietary
9.The association between eating out of home and overweight/obesity among Chinese adults
Keke CAO ; Yuna HE ; Xiaoguang YANG
Chinese Journal of Preventive Medicine 2014;(12):1088-1092
Objective To investigate the association between out-of-home eating ( OH eating) and overweight/obesity among adults in China.Methods A total of 33 828 subjects aged 18-60 years old from the 2002 China National Nutrition and Health Survey were selected to calculate their daily consumption of food and nutrition, when people eating at home or out-of-home.The 24-hour dietary recall method for 3 consecutive days was used to collect food intake information ( not including the condiment intake) .The logistic regression method was used to analyze the relationship between OH eating and overweight/obesity. Results The prevalence of OH eating among Chinese adults aged 18-60 years old was 28.3% ( 9 562/33 828) in 2002.Overall, the prevalence of OH eating was significantly greater among men compared to women(P<0.05), and the rate for men was 32.4%(5 117/15 805), and the rate for women was 24.7%(4 445/18 023).Besides, men who ate out of home showed a higher prevalence of overweight and obesity than those who ate at home ( P <0.05 ) , and the prevalence of overweight and obesity among them were 38.9%(1 991/5 117) and 31.7%(3 389/10 684), respectively.While women who ate at home showed a higher prevalence of overweight and obesity than those who ate out of home, and the prevalence of overweight and obesity among them were 38.1% ( 5 174/13 571 ) and 35.6% ( 1 581/4 445 ) , respectively.Compared with at-home eating group, 130.4 kJ energy, 12.2 g fat, 6.2 g protein and 67.1 mg sodium were excessively consumed per day for men, and 102.5 kJ energy, 8.6 g fat, 3.4 g protein and 60.6 mg sodium were excessively consumed per day for women.To sum up, OH eating was positively associated with overweight and obesity among men(OR=1.18,95%CI:1.09-1.27), but not among women(OR=0.94,95%CI:0.87-1.01).Conclusion OH eating was positively associated with overweight and obesity among men in China.
10.The association between eating out of home and overweight/obesity among Chinese adults
Keke CAO ; Yuna HE ; Xiaoguang YANG
Chinese Journal of Preventive Medicine 2014;(12):1088-1092
Objective To investigate the association between out-of-home eating ( OH eating) and overweight/obesity among adults in China.Methods A total of 33 828 subjects aged 18-60 years old from the 2002 China National Nutrition and Health Survey were selected to calculate their daily consumption of food and nutrition, when people eating at home or out-of-home.The 24-hour dietary recall method for 3 consecutive days was used to collect food intake information ( not including the condiment intake) .The logistic regression method was used to analyze the relationship between OH eating and overweight/obesity. Results The prevalence of OH eating among Chinese adults aged 18-60 years old was 28.3% ( 9 562/33 828) in 2002.Overall, the prevalence of OH eating was significantly greater among men compared to women(P<0.05), and the rate for men was 32.4%(5 117/15 805), and the rate for women was 24.7%(4 445/18 023).Besides, men who ate out of home showed a higher prevalence of overweight and obesity than those who ate at home ( P <0.05 ) , and the prevalence of overweight and obesity among them were 38.9%(1 991/5 117) and 31.7%(3 389/10 684), respectively.While women who ate at home showed a higher prevalence of overweight and obesity than those who ate out of home, and the prevalence of overweight and obesity among them were 38.1% ( 5 174/13 571 ) and 35.6% ( 1 581/4 445 ) , respectively.Compared with at-home eating group, 130.4 kJ energy, 12.2 g fat, 6.2 g protein and 67.1 mg sodium were excessively consumed per day for men, and 102.5 kJ energy, 8.6 g fat, 3.4 g protein and 60.6 mg sodium were excessively consumed per day for women.To sum up, OH eating was positively associated with overweight and obesity among men(OR=1.18,95%CI:1.09-1.27), but not among women(OR=0.94,95%CI:0.87-1.01).Conclusion OH eating was positively associated with overweight and obesity among men in China.

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